Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
315
datasets available to search
ShareScore release 0.9.0
Dataset results
315 results for “MTOR”
Survival and Proliferation of T-cell Acute Lymphoblastic Leukaemia Depends on mTOR-regulated Glutamine Uptake and EAAT1 Activity
GEO Series GSE101566. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Dectin1-Stimulated mTOR-C/EBPβ Signaling Induces IL-10-Producing Regulatory Tr2 Cells
GEO Series GSE87673. Mus musculus. 8 samples. Type: Expression profiling by array.
mTOR Inhibition Enables Long-Term Expansion of Human Neonatal Tracheal Aspirate-Derived Airway Basal Stem Cells
GEO Series GSE137950. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Increased tumourigenesis in ApcMin/+ mice fed with a Western-type diet associates with changes in PDK4, Erk/Akt and mTor pathways, intestinal immunity and the expression of energy metabolism-related g
GEO Series GSE85729. Mus musculus. 8 samples. Type: Expression profiling by array.
RNA-seq analysis of mTOR{delta}APC and WT lung and spleen APC subsets
GEO Series GSE100316. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing.
Phase I/Ii study of mTOR inhibitor everolimus and Hyper-CVAD plus RAD001 (Everolimus) chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia
GEO Series GSE60540. Homo sapiens. 10 samples. Type: Expression profiling by array.
Phenotypic rescue via mTOR inhibition in neuron-specific Pten knockout mice reveals AKT and mTORC1-site specific changes
GEO Series GSE288965. Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
Monocytes as endogenous immunologic biosensors: identification of inflammatory, adhesion, and mTOR-related signatures in psoriasis
GEO Series GSE161906. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic Repositioning Analysis Identifies mTOR Inhibitor as Potential Therapy for Epidermolysis Bullosa Simplex
GEO Series GSE179508. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Very low protein diets lead to reduced food intake and weight loss, linked to inhibition of hypothalamic mTOR signaling, in mice
GEO Series GSE158215. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Mtor knockout in PDAC cells
GEO Series GSE98860. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Lamtor5 maintains immune homeostasis by regulating lysosomal activity via v-ATPase and mTOR signaling
GEO Series GSE227039. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Preclinical Evaluation of Dual mTOR inhibitor, AZD2014, and Castration in Prostate Cancer
GEO Series GSE93897. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
mTOR inhibition by INK128 extends ovarian functions in aging and premature aging mice following germline stem cell transplantation
GEO Series GSE157325. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
EXP. 229_AC_RNAseq data of human cancer cell lines 94T778, SKBR3, AU565, SKMEL28 and A375 exposed to the selective MTOR inhibitor torkinib (PP242, Selleckchem, TX, USA) for 72 hours.
GEO Series GSE148344. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-dependent Regulation of α-cell Mass
GEO Series GSE68145. Homo sapiens; Mus musculus. 51 samples. Type: Expression profiling by array.
Integrating transcriptome, proteome, and phosphoproteome analysis reveals loss function of IQGAP2 promotes cell proliferation through the mTOR pathway
GEO Series GSE213715. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
mTOR signal in mitral valve diseases
GEO Series GSE293926. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "mTOR-Dependent Stimulation of IL20RA Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn's Disease."
<p>Crohn's disease (CD) is a chronic inflammatory condition that can affect different portions of the gastrointestinal tract. Lymphatic drainage was demonstrated to be dysfunctional in CD pathogenesis, ultimately causing the failure of the resolution of intestinal inflammation. To investigate the molecular mechanisms underlying these dysfunctions, we isolated human intestinal lymphatic endothelial cells (HILECs) from surgical specimens of patients undergoing resection for complicated CD (CD HILEC) and from a disease-free margin of surgical specimens of patients undergoing resection for cancer (healthy HILEC). Both cell types underwent transcriptomic profiling, and their barrier functionality was tested using a transwell-based co-culture system between HILEC and lamina propria mononuclear cells (LPMCs). Results showed CD HILEC displayed a peculiar transcriptomic signature that highlighted mTOR signaling as an orchestrator of leukocyte trafficking through the lymphatic barrier of CD patients. Moreover, we demonstrated that LPMC transmigration through the lymphatic endothelium of patients with CD depends on the capability of mTOR to trigger interleukin 20 receptor subunit α (IL20RA)-mediated intracellular signaling. Conclusively, our study suggests that leukocyte trafficking through the intestinal lymphatic microvasculature can be controlled by modulating IL20RA, thus leading to the resolution of chronic inflammation in patients with CD.</p>
Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours
ClinicalTrials.gov study NCT01194193. IPD Sharing: Not stated. Countries: 0. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.