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884 results for “Nicotine”
Project 1, Study 1: Investigating the Impact of Nicotine Using Spectrum Cigarettes
ClinicalTrials.gov study NCT01681875. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Do Flavors Increase the Addiction Potential of Nicotine?
ClinicalTrials.gov study NCT04696380. IPD Sharing: NO. Countries: 1. Publications: 1.
Nicotine Patch and Bupropion to Reduce Smoking Rates in Younger, Low-Income, and Minority Individuals
ClinicalTrials.gov study NCT00308763. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study to Examine the Pharmacodynamic Effects of GSK1034702 on Neurophysiological Biomarkers of Cognition in Nicotine Abstained Otherwise Healthy Smokers
ClinicalTrials.gov study NCT01371799. IPD Sharing: YES. Countries: 1. Publications: 2.
Depressed Mood Improvement Through Nicotine Dosing 3
ClinicalTrials.gov study NCT05746273. IPD Sharing: YES. Countries: 1. Publications: 6.
The ESTxENDS Trial- Electronic Nicotine Delivery Systems as an Aid for Smoking Cessation-extension of Follow-up
ClinicalTrials.gov study NCT04236791. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Effect of the Chromium Nicotinate on Type 2 Diabetes
ClinicalTrials.gov study NCT01368328. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Varenicline For Nicotine Vaping Cessation In Non Smoker Vaper Adolescents
ClinicalTrials.gov study NCT04602494. IPD Sharing: YES. Countries: 1. Publications: 0.
Bupropion as an Adjunct to the Nicotine Patch Plus CBT
ClinicalTrials.gov study NCT00142831. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies
ClinicalTrials.gov study NCT06471387. IPD Sharing: NO. Countries: 1. Publications: 1.
Targeting Mailed Nicotine Patch Distribution Interventions to Rural Regions of Canada
ClinicalTrials.gov study NCT04606797. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Pharmacokinetic Profile of Toxic Substances and Nicotine in Electronic Cigarettes
ClinicalTrials.gov study NCT01665066. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Combined Nortriptyline and Transdermal Nicotine for Smoking Cessation
ClinicalTrials.gov study NCT00018148. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Combination of Acupuncture, Auricular Acupressure and Nicotine Replacement Therapy for Smoking Cessation
ClinicalTrials.gov study NCT06931054. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Memory Improvement Through Nicotine Dosing (MIND) Study
ClinicalTrials.gov study NCT02720445. IPD Sharing: YES. Countries: 1. Publications: 6.
Brain Nicotine Receptor Density & Response to Nicotine Patch
ClinicalTrials.gov study NCT01526005. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Real-time eCounselling for Nicotine Addiction
ClinicalTrials.gov study NCT06544057. IPD Sharing: NO. Countries: 1. Publications: 5.
The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig) on Respiratory Symptoms
ClinicalTrials.gov study NCT03632421. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Toxin or medication? Immunotherapeutic effects of nicotine on a specialist caterpillar
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Data from: Evolution of vertebrate nicotinic acetylcholine receptors
Background: Many physiological processes are influenced by nicotinic acetylcholine receptors (nAChR), ranging from neuromuscular and parasympathetic signaling to modulation of the reward system and long-term memory. Due to the complexity of the nAChR family and variable evolutionary rates among its members, their evolution in vertebrates has been difficult to resolve. In order to understand how and when the nAChR genes arose, we have used a broad approach of analyses combining sequence-based phylogeny, chromosomal synteny and intron positions. Results: Our analyses suggest that there were ten subunit genes present in the vertebrate predecessor. The two basal vertebrate tetraploidizations (1R and 2R) then expanded this set to 19 genes. Three of these have been lost in mammals, resulting in 16 members today. None of the ten ancestral genes have kept all four copies after 2R. Following 2R, two of the ancestral genes became triplicates, five of them became pairs, and three seem to have remained single genes. One triplet consists of CHRNA7, CHRNA8 and the previously undescribed CHRNA11, of which the two latter have been lost in mammals but are still present in lizards and ray-finned fishes. The other triplet consists of CHRNB2, CHRNB4 and CHRNB5, the latter of which has also been lost in mammals. In ray-finned fish the neuromuscular subunit gene CHRNB1 underwent a local gene duplication generating CHRNB1.2. The third tetraploidization in the predecessor of teleosts (3R) expanded the repertoire to a total of 31 genes, of which 27 remain in zebrafish. These evolutionary relationships are supported by the exon-intron organization of the genes. Conclusions: The tetraploidizations explain all gene duplication events in vertebrates except two. This indicates that the genome doublings have had a substantial impact on the complexity of this gene family leading to a very large number of members that have existed for hundreds of millions of years.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.