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2,781
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2,781 results for “Older Adults”
Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
ClinicalTrials.gov study NCT00955903. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Safety and Immunogenicity of Three Dosage Levels of Swine Influenza Vaccine in Children Ages 3 to <9 Years, Adolescents 9 to <18 Years, Adults 18 to <65 Years and Elderly 65 Years and Older.
ClinicalTrials.gov study NCT01855945. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Hoarding Older Adults
ClinicalTrials.gov study NCT01227057. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults
ClinicalTrials.gov study NCT01869374. IPD Sharing: NO. Countries: 1. Publications: 4.
The Effects of Mixed Working Memory Training on Subsequent Training Gains Among Older Adults
ClinicalTrials.gov study NCT05672771. IPD Sharing: YES. Countries: 1. Publications: 8.
Treatment of Bipolar Mania in Older Adults
ClinicalTrials.gov study NCT00254488. IPD Sharing: Not stated. Countries: 2. Publications: 6.
Managing Pain and Cognitions in Older Adults With Mild Cognitive Impairment or Memory Related Problems and Chronic Pain
ClinicalTrials.gov study NCT04044183. IPD Sharing: NO. Countries: 1. Publications: 2.
Safety, Tolerability, and Immunogenicity Study of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Older Adults
ClinicalTrials.gov study NCT05297578. IPD Sharing: YES. Countries: 1. Publications: 1.
Effects of Melatonin on Insomnia Symptoms in Older Adults
ClinicalTrials.gov study NCT00230737. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Young and older adult vowel categorization responses
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Monitoring mobility in older adults using a global positioning system (GPS) smartwatch and accelerometer: A validation study
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The association between long-term air pollution exposure and Chinese visceral adiposity index: A nationwide study of middle-aged and older adults
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Community attachment as a factor in the subjective well-being of older adults in urban and rural areas: A case study in Tokyo, Osaka, and Shikoku region in Japan
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Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and habitual flavanol consumption
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Evaluation of equity in hospice care utilization among medicare-enrolled autistic older adults
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Orthostatic hypotension, dizziness, neurology outcomes, and death in older adults, supplement methods & tables, STROND checklist
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Finkel_Randerath_PLOSOne_Adapting affordance judgments to altered body properties in young and older adults
<p>Dataset belongs to publication in PLOSOne:</p> <p>Title: Does it still fit? – Adapting affordance judgments to altered body properties in young and older adults</p> <p>Authors: Lisa Finkel 1,2; Katharina Schmidt 1; Jean Patrick Philippe Scheib 1,2; Jennifer Randerath 1,2</p> <p>1: Department of Psychology, University of Konstanz, GER</p> <p>2: Lurija Institute for Rehabilitation Science and Health Research, Kliniken Schmieder, Allensbach, Germany</p> <p> </p>
Data from: Findings from an exploration of a social network intervention to promote diet quality and health behaviours in older adults with COPD: a feasibility study
<p><span><b>Background: </b>Diet quality in older people with Chronic Obstructive Pulmonary Disease (COPD) is associated with better health and lung function. Social factors, such as social support, social networks and participation in activities, have been linked with diet quality in older age. A social network tool – GENIE (Generating Engagement in Network Involvement) – was implemented in a COPD community care context. The study aimed to assess the feasibility of the GENIE intervention to promote diet quality and other health behaviours in COPD. </span></p> <p><span><b>Methods:</b> Twenty-two community-dwelling older adults with COPD were recruited from a local COPD Service. Participants were offered usual care or the GENIE intervention. Process evaluation methods were used to assess intervention implementation, context and mechanisms of impact; <a name="_Hlk11247522">these included observations of patient interactions with the intervention, documented in observational field notes and in films of a patient group discussion.</a> Diet quality was assessed by food frequency questionnaire; 'prudent' diet scores were used to describe diet quality at baseline and at 3-month follow-up. Change in diet quality was expressed per month, from baseline to follow-up.</span></p> <p><b>Results: </b>Feasibility data showed that the GENIE intervention could be implemented in this sample of community-living older people. The intervention was acceptable to clinicians and older people with COPD, especially for those with less severe disease, when facilitated appropriately and considering the levels of literacy of participants. There was no significant change in diet quality in the intervention group over the follow-up period (median change in prudent diet score per month, (interquartile range (IQR)): 0.03, (-0.24 – 0.07)); whereas an overall fall in diet quality was observed in the control group (-0.15, (-0.24 – 0.03)).</p> <p><span><b>Conclusion: </b>The process evaluation findings suggest that this intervention is feasible and acceptable to both patients and clinicians. Although the sample size achieved in this study was small, findings suggest that the intervention may have a protective effect against declines in diet quality, and other health behaviours, in an older COPD population. Findings from this feasibility study indicate that further evaluation of the GENIE intervention is warranted in a larger study, with a longer follow-up.</span></p> <p> </p> <p> </p>
Data from: Endovascular treatment in older adults with acute ischemic stroke in the MR CLEAN Registry
<p><strong>Objective</strong>: To explore clinical outcomes in older adults with acute ischemic stroke treated with endovascular thrombectomy (EVT).</p> <p><strong>Methods</strong>: We included consecutive patients (2014–2016) with an anterior circulation occlusion undergoing EVT from the MR CLEAN Registry. We assessed the effect of age (dichotomized at ≥80 years, and as continuous variable) on the modified Rankin Scale [mRS] score at 90 days, symptomatic intracranial hemorrhage (sICH), and reperfusion rate. The association between age and mRS was assessed with multivariable ordinal logistic regression, and a multiplicative interaction term was added to the model to assess modification of reperfusion by age on outcome.</p> <p><strong>Results</strong>: 380/1526 (25%) of patients were 80 years or older (=older adults). Older adults had a worse functional outcome than younger patients (adjusted common OR for an mRS shift towards better outcome: 0.31, 95%CI 0.24–0.39). Mortality was also higher in older adults (51% vs. 22%, aOR 3.12, 95%CI 2.33–4.19). There were no differences in proportion of patients with mRS 4-5, sICH, or reperfusion rates. Successful reperfusion was more strongly associated with a shift towards good functional outcome in older adults than in younger patients (acOR 3.22, 95%CI 2.04–5.10 vs. 2.00, 95%CI 1.56–2.57, P<sub>interaction</sub>=0.026).</p> <p><strong>Conclusion</strong>: Older age is associated with an increased absolute risk of poor clinical outcome, while the relative benefit of successful reperfusion seems to be higher in these patients. These results should be taken into consideration when selecting older adults for EVT.</p>
Data from: 8-year trends in physical activity, nutrition, TV viewing time, smoking, alcohol and BMI: a comparison of younger and older Queensland adults
Lifestyle behaviours significantly contribute to high levels of chronic disease in older adults. The aims of the study were to compare the prevalence and the prevalence trends of health behaviours (physical activity, fruit and vegetable consumption, fast food consumption, TV viewing, smoking and alcohol consumption), BMI and a summary health behaviour indicator score in older (65+ years) versus younger adults (18-65 years). The self-report outcomes were assessed through the Queensland Social Survey annually between 2007-2014 (n=12,552). Regression analyses were conducted to compare the proportion of older versus younger adults engaging in health behaviours and of healthy weight in all years combined and examine trends in the proportion of younger and older adults engaging in health behaviours and of healthy weight over time. Older adults were more likely to meet recommended intakes of fruit and vegetable (OR=1.43, 95%CI=1.23-1.67), not consume fast food (OR=2.54, 95%CI=2.25-2.86) and be non-smokers (OR=3.02, 95%CI=2.53-3.60) in comparison to younger adults. Conversely, older adults were less likely to meet the physical activity recommendations (OR=0.86, 95%CI= 0.78-0.95) and watch less than 14 hours of TV per week (OR=0.65, 95%CI=0.58-0.74). Overall, older adults were more likely to report engaging in 3, or at least 4 out of 5 healthy behaviours. The proportion of both older and younger adults meeting the physical activity recommendations (OR=0.97, 95%CI=0.95-0.98 and OR=0.94, 95%CI=0.91-0.97 respectively), watching less than 14 hours of TV per week (OR=0.96, 95%CI=0.94-0.99 and OR=0.94, 95%CI=0.90-0.99 respectively) and who were a healthy weight (OR=0.95, 95%CI=0.92-0.99 and OR=0.96, 95%CI=0.94-0.98 respectively) decreased over time. The proportion of older adults meeting the fruit and vegetable recommendations (OR=0.90, 95%CI=0.84-0.96) and not consuming fast food (OR=0.94, 95%CI=0.88-0.99) decreased over time. Although older adults meet more health behaviours than younger adults, the decreasing prevalence of healthy nutrition behaviours in this age group needs to be addressed.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.