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Dataset results
289 results for “data reduction”
STAVER: A Standardized Dataset-Based Algorithm for Efficient Variation Reduction in Large-Scale DIA MS Data
<p>This project focuses on the development and application of STAVER, a standardized dataset-based algorithm designed to reduce variation in large-scale data-independent acquisition (DIA) mass spectrometry data. By using a reference dataset to standardize mass spectrometry signals, STAVER effectively reduces noise and enhances protein quantification accuracy, especially in the context of multi-library search. The effectiveness of STAVER is demonstrated in several large-scale DIA datasets, showing improved identification and quantification of thousands of proteins. The project aims to promote the adoption of multi-library search and improve the quality of DIA proteomics data through the open-source STAVER software package.</p>
The Role of Undercoordinated Sites on Zinc Electrodes for CO2 Reduction to CO (Data Set)
<p>The dataset for the manuscript.</p>
Data set related to the article: "Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline"
<p>As we age, our body experiences chronic, systemic inflammation contributing to the morbidity and mortality of the elderly. The senescent immune system has been described to have a causal role in driving systemic aging and therefore may represent a key therapeutic target to prevent pathological consequences associated with aging and extend a healthy lifespan. Previous studies from our group associated a polymorphic haplotype variant in the BPIFB4 gene (LAV-BPIFB4) with exceptional longevity. Transfer of the LAV-BPIFB4 in preclinical models halted the progression of cardiovascular diseases (CVDs) and frailty by counterbalancing chronic inflammation. In the present study, we aimed to delineate the action of systemic adeno-associated viral vector-mediated LAV-BPIFB4 gene transfer (AAV-LAV-BPIFB4) on the deleterious age-related changes of the immune system and thereby the senescence-associated events occurring in C57BL/6J mice aged 26 months. Our in vivo data showed that 26-months-old mice had a higher frequency of CD45+SA-beta Gal+ immune cells in peripheral blood than young (4-months-old) C57BL/6J mice. Notably, AAVLAV-BPIFB4 gene transfer in aged mice reduced the pool of peripheral immunosenescent cells that were shown to be enriched in the spleen. In addition, the proper tuning of the immune secretory phenotype (IL1βlow, IL6low, IL10high) associated with a significant reduction in SA-beta Gal-positive area of aorta from AAV-LAV treated mice. At the functional level, the reduction of senescenceassociated inflammation ensured sustained NAD+ levels in the plasma of AAV-LAV-BPIFB4 old mice by preventing the NADase CD38 increase in F4/80+ tissue-resident macrophages and Ly6Chigh pro-inflammatory monocytes of the spleen and bone marrow. Finally, to validate the clinical implication of our findings, we showed that Long-living-individuals (LLIs, >95 years), which delay CVDs onset, especially if LAV-carriers, were characterized by high NAD+ levels. In conclusion, the new senotherapeutic action of LAV-BPIFB4 may offer a valuable therapeutic tool to control aging and reduce the burden of its pathophysiological disorders, such as CVDs.</p>
Data_Electrochemical Reduction of CO2: Effect of Convective CO2 Supply in Gas Diffusion Electrodes
<p>The folder contains the processed data of figures 3, 4, 5 and 6 that appear in:</p> <p>M. Duarte, B. De Mot, J. Hereijgers, T. Breugelmans, Electrochemical Reduction of CO2: Effect of Convective CO2 Supply in Gas Diffusion Electrodes, ChemElectroChem. 6 (2019)</p> <p><a href="https://doi.org/10.1002/celc.201901454">https://doi.org/10.1002/celc.201901454</a></p>
Data_Bifunctional Nickel-Nitrogen-Doped-Carbon-Supported Electrocatalyst for CO2 Reduction
<p>The folder contains the processed data of figures 1, 2, 3, 4, 5 that appear in:</p> <p>Choukroun, D.; Daems, N.; Kenis, T.; Van Everbroeck, T.; Hereijgers, J.; Altantzis, T.; Bals, S.; Cool, P.; Breugelmans, T., Bifunctional Nickel–Nitrogen-Doped-Carbon-Supported Copper Electrocatalyst for CO<sub>2</sub> Reduction. <em>The Journal of Physical Chemistry C </em><strong>2020</strong>, <em>124</em>, 1369-1381.The processing method is described in the article (10.1021/acs.jpcc.9b08931).</p>
Data_Electrochemical reduction of halogenated aromatic compounds at metal cathodes in acetonitrile
<p>The folder contains the processed data of figures 2, 3, 4, 5, 6, 7, S9, S10, S11, S12, S13 and S14 that appear in:</p> <p>S. Neukermans, F. Vorobjov, T. Kenis, R. De Wolf, J. Hereijgers, T. Breugelmans, Electrochemical reduction of halogenated aromatic compounds at metal cathodes in acetonitrile, Electrochimica acta, 332 (2020) 135484.</p> <p>https://doi.org/10.1016/j.electacta.2019.135484</p>
Data_Nickel-containing N-doped carbon as effective electrocatalysts for the reduction of CO2 to CO in a continuous-flow electrolyzer.
<p>The folder contains the processed data of figures 7, 8, 9, 10, 11, 12, S1, S11, S12, S14 & S15 that appear in:</p> <p>N. Daems, B. De Mot, D. Choukroun, K. Van Daele, C. Li, A. Hubin, S. Bals, J. Hereijgers and T. Breugelmans, Nickel-containing N-doped carbon as effective electrocatalysts for the reduction of CO<sub>2</sub> to CO in a continuous-flow electrolyzer, Sustainable Energy & Fuels, 2020,<strong>4</strong>, 1296-1311</p> <p>The processing method is described in the article (https://doi.org/10.1039/c9se00814d).</p>
Implementing high dimensional reductional analysis on histocytometric data
<p>In the previous protocol article (Munoz-Erazo, Schmidt, Shinko, Eccles, et al., 2022), we demonstrated construction of a histocytometry pipeline that is capable of both segmenting highly-aggregated cell populations and retaining the original intensity data range of the input microscopic images. In the protocol article presented here, using the output from the aforementioned protocol article, we demonstrate how to phenotype the data using the high dimensional reductional analysis technique opt-t-SNE (optimized t-distributed Stochastic Neighbor Embedding) and compare it to traditional manual gating.</p> <p>Additional, we present a support protocol illustrating the advantage of the inclusion of cell junction/membrane marker in accurately segmenting highly-aggregated cell populations in ilastik.</p> <p>In the previous protocol article (Munoz-Erazo, Schmidt, Shinko, Eccles, et al., 2022), we demonstrated construction of a histocytometry pipeline that is capable of both segmenting highly-aggregated cell populations and retaining the original intensity data range of the input microscopic images. In the protocol article presented here, using the output from the aforementioned protocol article, we demonstrate how to phenotype the data using the high dimensional reductional analysis technique opt-t-SNE (optimized t-distributed Stochastic Neighbor Embedding) and compare it to traditional manual gating.</p> <p>Additional, we present a support protocol illustrating the advantage of the inclusion of cell junction/membrane marker in accurately segmenting highly-aggregated cell populations in ilastik.</p>
Data for "On data reduction methods for volcanic tremor characterization: The 2012 eruption of Copahue volcano, Southern Andes"
<p>MiniSEED data for Z, E, and N channels of the CNA station.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.