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621
datasets available to search
ShareScore release 0.9.0
Dataset results
621 results for “frailty”
Pilot Mobile for Dementia and Frailty
ClinicalTrials.gov study NCT05827094. IPD Sharing: NO. Countries: 1. Publications: 0.
Metformin for Preventing Frailty in High-risk Older Adults
ClinicalTrials.gov study NCT02570672. IPD Sharing: Not stated. Countries: 1. Publications: 0.
FOCUS- Frailty Management Optimization Through EIP AHA Commitments and Utilization of Stakeholders Input
ClinicalTrials.gov study NCT03194412. IPD Sharing: NO. Countries: 1. Publications: 0.
Treating Frailty in Lung Transplant Candidates (PREHAB)
ClinicalTrials.gov study NCT03457545. IPD Sharing: NO. Countries: 0. Publications: 23.
FRailty WAlking Patterns (FRAP) Study
ClinicalTrials.gov study NCT02755129. IPD Sharing: NO. Countries: 1. Publications: 0.
E-health Brisk Walking in Older People With Cognitive Frailty
ClinicalTrials.gov study NCT05758740. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Xerostomia in Patients With a Life-limiting Condition or Frailty
ClinicalTrials.gov study NCT05506137. IPD Sharing: NO. Countries: 0. Publications: 2.
An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer
ClinicalTrials.gov study NCT04733534. IPD Sharing: YES. Countries: 1. Publications: 0.
Usefulness of Cardiopulmonary Exercise Testing for Cardiovascular Risk Estimation and Frailty Assessment in Liver Transplant Candidates
ClinicalTrials.gov study NCT04543825. IPD Sharing: NO. Countries: 1. Publications: 0.
DNA methylation signatures of injection illicit drug use (IDU) and hepatitis C (HCV) predict HIV pathophysiologic frailty I
GEO Series GSE100264. Homo sapiens. 386 samples. Type: Methylation profiling by genome tiling array.
Frailty in middle age is associated with race-specific changes to the transcriptome.
GEO Series GSE129534. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty II
GEO Series GSE107080. Homo sapiens. 405 samples. Type: Methylation profiling by genome tiling array.
Transcriptomic and metabolomic changes might predict frailty in SAMP8 mice
GEO Series GSE270589. Mus musculus. 41 samples. Type: Expression profiling by high throughput sequencing.
Hematopoietic progenitor cell liabilities and alarmins S100A8/A9 – related inflammaging associate with frailty and predict poor cardiovascular outcomes in older adults
GEO Series GSE190446. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
The impact of physical frailty on the response to inactivated influenza vaccine in older adults
GEO Series GSE196793. Homo sapiens. 84 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic signature of frailty in elderly patients with cardiovascular disease
GEO Series GSE287726. Homo sapiens. 70 samples. Type: Expression profiling by high throughput sequencing.
Data from: Imaging markers of small vessel disease and 'brain frailty' and outcomes in acute stroke
Objective: We assessed the association of baseline imaging markers of cerebral small vessel disease (SVD) and 'brain frailty' with clinical outcome after acute stroke in the Efficacy of Nitric Oxide in Stroke (ENOS) trial. Methods: ENOS randomised 4011 patients with acute stroke (<48 hours of onset) to transdermal glyceryl trinitrate (GTN) or no GTN for 7 days. The primary outcome was functional outcome (modified Rankin Scale, mRS) at day 90. Cognition was assessed via telephone at day 90. Stroke syndrome was classified using the Oxfordshire Community Stroke Project classification. Brain imaging was adjudicated masked to clinical information and treatment, and assessed SVD (leukoaraiosis, old lacunar infarcts/lacunes, atrophy) and 'brain frailty' (leukoaraiosis, atrophy, old vascular lesions/infarcts). Analyses used ordinal logistic regression adjusted for prognostic variables. Results: In all participants and those with lacunar syndromes (LACS, 1397, 34.8%), baseline CT imaging features of SVD and 'brain frailty' were common and independently associated with unfavourable shifts in mRS at day 90: all participants (SVD score OR 1.15, 95% CI 1.07-1.24; 'brain frailty' score OR 1.25, 95% CI 1.17-1.34); those with LACS (SVD score OR 1.30, 95% CI 1.15-1.47; 'brain frailty' score OR 1.28, 95% CI 1.14-1.44). 'Brain frailty' was associated with worse cognitive scores at 90 days in all and in LACS participants. Conclusions: Baseline imaging features of SVD and 'brain frailty' were common in lacunar stroke and all stroke, predicted worse prognosis after all acute stroke with a stronger effect in lacunar stroke, and may aid future clinical decision-making. Registration: ISRCTN99414122.
Study to Assess the Safety and Effects of Autologous Adipose-Derived Stem Cells in Patients With Frailty Syndrome
ClinicalTrials.gov study NCT01501461. IPD Sharing: Not stated. Countries: 1. Publications: 0.
FRAILTY Classification Algorithm for the Corsano CARDIOWATCH 287-2: a Development and Validation Study
ClinicalTrials.gov study NCT06930833. IPD Sharing: NO. Countries: 1. Publications: 0.
Precision Stratification for Frailty and Cognitive Decline
ClinicalTrials.gov study NCT07081282. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.