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291
datasets available to search
ShareScore release 0.9.0
Dataset results
291 results for “myoblasts”
Skeletal myoblasts protect cardiomyocytes against oxidative stress via c-Met and epidermal growth factor receptor (EGFR)-dependent paracrine pathways
GEO Series GSE35393. Rattus norvegicus. 3 samples. Type: Expression profiling by array.
ChIP-seq Profiling of RXRα in Proliferating C2C12 Myoblasts
GEO Series GSE279060. Mus musculus. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide mapping of MEF2A binding sites by CUT&Tag-seq in chicken primary myoblasts
GEO Series GSE249097. Gallus gallus. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
C2C12 myoblast vs myotube
GEO Series GSE3243. Homo sapiens; Mus musculus. 6 samples. Type: Expression profiling by array.
Transcriptomic analysis of BMP4/GREM1 stimulation on primary myoblasts
GEO Series GSE145694. Mus musculus. 9 samples. Type: Expression profiling by array.
Gene expression response to DUX4 in murine myoblasts
GEO Series GSE77100. Mus musculus. 18 samples. Type: Expression profiling by array.
Human Sarcopenic Myoblasts Can Be Rescued by Pharmacological Reactivation of HIF-1α
<p>Cirillo F, Mangiavini L, La Rocca P, Piccoli M, Ghiroldi A, Rota P, Tarantino A, Canciani B, Coviello S, Messina C, Ciconte G, Pappone C, Peretti GM, Anastasia L. Human Sarcopenic Myoblasts Can Be Rescued by Pharmacological Reactivation of HIF-1α. Int J Mol Sci. 2022 Jun 26;23(13):7114. doi: 10.3390/ijms23137114. PMID: 35806119; PMCID: PMC9267002.</p> <p>Abstract</p> <p>Sarcopenia, an age-related decline in muscle mass and strength, is associated with metabolic disease and increased risk of cardiovascular morbidity and mortality. It is associated with decreased tissue vascularization and muscle atrophy. In this work, we investigated the role of the hypoxia inducible factor HIF-1α in sarcopenia. To this end, we obtained skeletal muscle biopsies from elderly sarcopenic patients and compared them with those from young individuals. We found a decrease in the expression of HIF-1α and its target genes in sarcopenia, as well as of <em>PAX7</em>, the major stem cell marker of satellite cells, whereas the atrophy marker MURF1 was increased. We also isolated satellite cells from muscle biopsies and cultured them in vitro. We found that a pharmacological activation of HIF-1α and its target genes caused a reduction in skeletal muscle atrophy and activation of <em>PAX7</em> gene expression. In conclusion, in this work we found that HIF-1α plays a role in sarcopenia and is involved in satellite cell homeostasis. These results support further studies to test whether pharmacological reactivation of HIF-1α could prevent and counteract sarcopenia.</p> <p> </p>
Unexpected distinct roles of the related histone H3 lysine 9 methyltransferases G9a and G9a-Like Protein in myoblasts
GEO Series GSE72626. Mus musculus. 7 samples. Type: Expression profiling by array.
FM95-14 Fetal Myoblast Differentiation Time Series
GEO Series GSE3780. Homo sapiens. 60 samples. Type: Expression profiling by array.
Valine enhances intramuscular fat deposition through activating autophagy and fatty acid metabolism pathways in C2C12 myoblasts
GEO Series GSE217813. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Organoid Culture Promotes Dedifferentiation of Mouse Myoblasts into Stem Cells Capable of Complete Muscle Regeneration
GEO Series GSE267952. Mus musculus. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.