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765 results for “rhythm”
Figure 1 from: Espinasa L, Collins E, Finocchiaro A, Kopp J, Robinson J, Rutkowski J (2016) Incipient regressive evolution of the circadian rhythms of a cave amphipod. Subterranean Biology 20: 1-13. https://doi.org/10.3897/subtbiol.20.10010
Figure 1 - Adult and juvenile specimens of Stygobromus allegheniensis from Ice Cave #1 at Sam's Point Preserve. As is typical of cave-adapted organisms, this species is depigmented, has long appendages, and is fully eyeless. Nonetheless, it can detect light and actively avoids it.
Figure 4 from: Espinasa L, Collins E, Finocchiaro A, Kopp J, Robinson J, Rutkowski J (2016) Incipient regressive evolution of the circadian rhythms of a cave amphipod. Subterranean Biology 20: 1-13. https://doi.org/10.3897/subtbiol.20.10010
Figure 4 - Motor activity followed periods of light or darkness regardless of the time of the day. Individuals on the left (A–C) are the same as individuals on the right (A'–C'). Black boxes indicate periods while in darkness and white boxes indicate illuminated conditions.
Figure 5 from: Espinasa L, Collins E, Finocchiaro A, Kopp J, Robinson J, Rutkowski J (2016) Incipient regressive evolution of the circadian rhythms of a cave amphipod. Subterranean Biology 20: 1-13. https://doi.org/10.3897/subtbiol.20.10010
Figure 5 - Entrainment by light is apparently not functioning in the Ice Cave (A–C and A'–C') and Clarksville Cave (D–G) populations. In Stygobromus allegheniensis, the second dark period lacks the anticipation and synchronization of a period of activity, which is a hallmark of organisms possessing a light-entrained circadian rhythm. Black boxes indicate periods while in darkness and white boxes indicate illuminated conditions.
RHYTHM AND THE BASICS OF ITS DEFINITION
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Dataset: Rhythm Pharmaceuticals, Inc. (RYTM) Stock Performance
This dataset provides historical stock market performance data for specific companies. It enables users to analyze and understand the past trends and fluctuations in stock prices over time. This information can be utilized for various purposes such as investment analysis, financial research, and market trend forecasting.
Data from: Effects of 4-Hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on liver transcriptome in rats: implication in the disruption of circadian rhythm and fatty acid metabolism
Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) have been detected in tissues of both wild animals and humans. Several previous studies have suggested adverse effects of OH-PCBs on the endocrine and nervous systems in mammals. However, there have been no studies on transcriptome analysis of the effects of OH-PCBs, and thus, the whole picture and mechanisms underlying the adverse effects induced by OH-PCBs are still poorly understood. We therefore investigated the mRNA expression profile in the liver of adult male Wistar rats treated with 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) to explore the genes responsive to OH-PCBs and to understand the potential effects of the chemical. Next-generation RNA sequencing analysis revealed changes in the expression of genes involved in the circadian rhythm and fatty acid metabolism, such as nuclear receptor subfamily 1, group D, member 1 (Nr1d1), aryl hydrocarbon receptor nuclear translocator-like protein 1 (Arntl), cryptochrome circadian clock 1 (Cry1), and enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase (Ehhadh), in 4-OH-CB107-treated rats. In addition, biochemical analysis of the plasma revealed a dose-dependent increase in the leucine aminopeptidase (LAP), indicating the onset of liver damage. These results suggest that OH-PCB exposure may induce liver injury as well as disrupt the circadian rhythm and peroxisome proliferator-activated receptor (PPAR)-related fatty acid metabolism.
Data from: Neural mechanisms of rhythm-based temporal prediction: delta phase-locking reflects temporal predictability but not rhythmic entrainment
Predicting the timing of upcoming events enables efficient resource allocation and action preparation. Rhythmic streams, such as music, speech, and biological motion, constitute a pervasive source for temporal predictions. Widely accepted entrainment theories postulate that rhythm-based predictions are mediated by synchronizing low-frequency neural oscillations to the rhythm, as indicated by increased phase concentration (PC) of low-frequency neural activity for rhythmic compared to random streams. However, we show here that PC enhancement in scalp recordings is not specific to rhythms but is observed to the same extent in less periodic streams if they enable memory-based prediction. This is inconsistent with the predictions of a computational entrainment model of stronger PC for rhythmic streams. Anticipatory change in alpha activity and facilitation of electroencephalogram (EEG) manifestations of response selection are also comparable between rhythm- and memory-based predictions. However, rhythmic sequences uniquely result in obligatory depression of preparation-related premotor brain activity when an on-beat event is omitted, even when it is strategically beneficial to maintain preparation, leading to larger behavioral costs for violation of prediction. Thus, while our findings undermine the validity of PC as a sign of rhythmic entrainment, they constitute the first electrophysiological dissociation, to our knowledge, between mechanisms of rhythmic predictions and of memory-based predictions: the former obligatorily lead to resonance-like preparation patterns (that are in line with entrainment), while the latter allow flexible resource allocation in time regardless of periodicity in the input. Taken together, they delineate the neural mechanisms of three distinct modes of preparation: continuous vigilance, interval-timing-based prediction and rhythm-based prediction.
Data from: Distributed rhythm generators underlie Caenorhabditis elegans forward locomotion
Coordinated rhythmic movements are ubiquitous in animal behavior. In many organisms, chains of neural oscillators underlie the generation of these rhythms. In C. elegans, locomotor wave generation has been poorly understood; in particular, it is unclear where in the circuit rhythms are generated, and whether there exists more than one such generator. We used optogenetic and ablation experiments to probe the nature of rhythm generation in the locomotor circuit. We found that multiple sections of forward locomotor circuitry are capable of independently generating rhythms. By perturbing different components of the motor circuit, we localize the source of secondary rhythms to cholinergic motor neurons in the midbody. Using rhythmic optogenetic perturbation, we demonstrate bidirectional entrainment of oscillations between different body regions. These results show that, as in many other vertebrates and invertebrates, the C. elegans motor circuit contains multiple oscillators that coordinate activity to generate behavior.
Intra-population genetic variation in the level and rhythm of daily activity in Drosophila immigrans
<p>Genetic diversity within a population, such as polymorphisms and personality, is considered to improve population performance because such intraspecific variations have the potential to alleviate the competition for a limited resource or the risk of predation and sexual harassment at a population-level. Variation in the level and rhythm of daily activity in a population could also affect population performance by directly altering ecological, social, and sexual interactions among individuals. However, it remains to be elucidated whether such intra-population variation in the level and rhythms of daily activity exists in a natural population. Here, we investigated the genetic variation in daily activity within a single natural population of Drosophila immigrans. We established 21 isofemale lines from a single natural population, and measured larval activity level and the level and daily pattern of adult activity over a 24 h period. Larval activity level significantly varied among isofemale lines. Likewise, the activity level in the adult stage significantly varied among lines. The significant variation was also found in the daily pattern of adult activity; some lines showed greater activity level in the daytime, and others showed greater activity level in the night. Our results consistently suggest that there is a genetic variation in behavioral activity in a natural population, probably contributing to shaping the population performance.</p>
Clinical Efficacy of Potassium Canrenoate in Sinus Rhythm Restoration Among Patients With Atrial Fibrillation.
ClinicalTrials.gov study NCT03536806. IPD Sharing: UNDECIDED. Countries: 0. Publications: 2.
Incidence and Morbidity of Cardiac Rhythm Disorders in Patients Assisted by ECMO-VA for Refractory Cardiogenic Shock
ClinicalTrials.gov study NCT05788120. IPD Sharing: YES. Countries: 1. Publications: 0.
Sensorimotor Rhythm Brain-Computer Interface Switch to Operate Assistive Technology
ClinicalTrials.gov study NCT01117727. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Rhythm-based Intervention in Aphasia
ClinicalTrials.gov study NCT04581564. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical Randomised Phase 2 Trial of AP31969 Versus Placebo for Rhythm Control of Atrial Fibrillation
ClinicalTrials.gov study NCT07267949. IPD Sharing: YES. Countries: 7. Publications: 0.
Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia
ClinicalTrials.gov study NCT05248295. IPD Sharing: NO. Countries: 1. Publications: 0.
Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM)
ClinicalTrials.gov study NCT00000556. IPD Sharing: Not stated. Countries: 0. Publications: 28.
Cardiac Magnetic Resonance Predictors of Outcome of Rhythm Control in Patients with Atrial Fibrillation/Flutter
ClinicalTrials.gov study NCT06758895. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Modulation of Brain Rhythms in Stroke
ClinicalTrials.gov study NCT07121582. IPD Sharing: YES. Countries: 1. Publications: 0.
Effects of Sex Hormones on Circadian Rhythm in Men and Women
ClinicalTrials.gov study NCT00001285. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients
ClinicalTrials.gov study NCT01284140. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.