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Dataset results
3,430 results for “PD”
Next Generation Sequencing Facilitates Quantitative Analysis of the effects of PD-1 deficiency on sorted mouse pulmonary ILC2 Transcriptomes
GEO Series GSE153909. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Anti-PD-1 re-navigates concealed IL-15 to rejuvenate tumor-specific PD-1+CD8+T cells inside the tumor microenvironment
GEO Series GSE212545. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy.
GEO Series GSE161353. Homo sapiens; Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
Gene Expression Profiling of human monocytes: Combination Therapy with Anti–CTLA-4 and Anti–PD-1 Leads to Distinct Immunologic Changes In Vivo
GEO Series GSE77924. Homo sapiens. 39 samples. Type: Expression profiling by array.
Induced expression of PD-L1 in spermatogonial stem cells by self-renewal division allows allogeneic offspring production [microarray]
GEO Series GSE129546. Mus musculus. 10 samples. Type: Expression profiling by array.
Comparison of gene expression profiles of Jurkat cells with or without PD-1 ligation
GEO Series GSE24026. Homo sapiens. 11 samples. Type: Expression profiling by array.
Gene expression based outcome of CT-26 tumor in C57/BL6 mice after treatment with anti-PD-1 antibody, GITR-L, combination or Bispecific molecules
GEO Series GSE189359. Mus musculus. 100 samples. Type: Expression profiling by array.
Expression data from PD-1+/- Th cells
GEO Series GSE199687. Mus musculus. 2 samples. Type: Expression profiling by array.
Targeting VRK2 Enhances the Efficacy of Anti-PD-1 Therapy in Hepatocellular Carcinoma by Reducing Direct Phosphorylation and Stability of MYC: CUT-TAG sequencing for MYC in hepatocellular carcinoma ce
GEO Series GSE278073. Homo sapiens. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A tumor specific super-enhancer drives immune evasion by guiding synchronous expression of PD-L1 and PD-L2
GEO Series GSE135016. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Epigenome-wide association analysis on weighted life events in PD patients - discovery cohort
GEO Series GSE200954. Homo sapiens. 109 samples. Type: Methylation profiling by genome tiling array.
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5]
GEO Series GSE103711. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Basal ganglia Beta oscillations and Insomnia in PD
<p>Accompanying dataset for our PNAS paper from July 2020</p>
A dysfunctional T cell gene signature for predicting non-response to PD-1 blockade in non-small cell lung cancer that is suitable for routine clinical diagnostics
<p>Since PD-1 blockade is only effective in a minority of patients with advanced stage NSCLC, biomarkers are needed to guide treatment decisions. Tumor infiltration by PD-1T TILs, a dysfunctional tumor-infiltrating lymphocyte (TIL) pool with tumor-reactive capacity, can be detected by digital quantitative IHC and has been established as a novel predictive biomarker in NSCLC. To facilitate translation of this biomarker to the clinic, we here aimed to develop a robust RNA signature reflecting a tumor's PD-1T TIL status.,mRNA expression analysis using Nanostring was performed in baseline tumor samples from 41 advanced stage NSCLC patients treated with nivolumab that were selected based on PD-1T TIL infiltration by IHC. Samples were included as training cohort (n=41) to develop a predictive gene signature. This signature was independently validated in a second cohort (n=42). Primary outcome was disease control at 12 months (DC 12m) and secondary outcome was progression-free and overall survival. ,Regularized regression analysis yielded a signature using 12 out of 56 differentially expressed genes between PD-1T IHC high tumors from patients with DC 12m and PD-1T IHC low tumors from patients with progressive disease (PD). In the validation cohort 6/6 (100%) patients with DC 12m and 23/36 (64%) with PD were correctly classified with an NPV of 100% and a PPV of 32%.,The PD-1T mRNA signature showed a similar high sensitivity and high NPV as the digital IHC quantification of PD-1T TILs. This provides a straightforward approach allowing for easy implementation in a routine diagnostic clinical setting.</p>
Data Repository: Human iPSC-derived pericyte-like cells carrying LRRK2 mutation induce a reactive phenotype and alters migration (PD lines differentiated with TGFb3)
<p>Data Repository for publication: Human iPSC-derived pericyte-like cells carrying LRRK2 mutation induce a reactive phenotype and alters migration (PD lines differentiated with TGFb3)</p>
Novel Strategy to Regulate PD-L1 Expression and Enhance Anti-Tumor Effect
<p>Figs source data</p>
PD-L1 immunoexpression as an early predictive biomarker: an analysis in cases of Oral Potentially Malignant Disorder (OPMD) and Oral Squamous Cell Carcinoma (OSCC).
<p>Master chart for Oral Potentially Premalignant and Oral Squamous Cell Carcinoma cases.</p>
Lymphoplasmacyte-rich meningioma with hematologic signs and PD-L1 over-expression
Open the record for dataset details and reuse information.
Serum Autoantibodies in Predicting the Efficacy of Anti-PD-1 Treatment in Patients With Advanced NSCLC
ClinicalTrials.gov study NCT04372732. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Asymmetric DBS for PD : A Multicenter, Prospective, Single Arm, Open Label Study
ClinicalTrials.gov study NCT04616521. IPD Sharing: Not stated. Countries: 0. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.