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3,878 results for “Molecular Data”
Figures 127-130 from: Jordaens K, Goergen G, Skevington JH, Kelso S, De Meyer M (2021) Revision of the Afrotropical species of the hover fly genus Mesembrius Rondani (Diptera, Syrphidae) using morphological and molecular data. ZooKeys 1046: 1-141. https://doi.org/10.3897/zookeys.1046.57052
Figures 127-130 Mesembrius spp., right wing 127M. arcuatus sp. nov. (♂) 128M. caffer (Loew) (nominal morph) (♂) 129M. capensis (Macquart) (♂) 130M. chapini Curran (♂).
Figures 113-118 from: Jordaens K, Goergen G, Skevington JH, Kelso S, De Meyer M (2021) Revision of the Afrotropical species of the hover fly genus Mesembrius Rondani (Diptera, Syrphidae) using morphological and molecular data. ZooKeys 1046: 1-141. https://doi.org/10.3897/zookeys.1046.57052
Figures 113-118 Mesembrius spp., abdomen, dorsal view 113M. cyanipennis (Bezzi) (♀) 114M. maculifer Hull (♀) 115M. madagascariensis Keiser (♀) 116M. minor (Bezzi) (♀) 117M. morio (Bezzi) (♀) 118M. platytarsis Curran syn. nov. (♀).
Figures 58-63 from: Jordaens K, Goergen G, Skevington JH, Kelso S, De Meyer M (2021) Revision of the Afrotropical species of the hover fly genus Mesembrius Rondani (Diptera, Syrphidae) using morphological and molecular data. ZooKeys 1046: 1-141. https://doi.org/10.3897/zookeys.1046.57052
Figures 58-63 Mesembrius spp., head, frontal view 58M. nigriceps Curran (♂) 59M. perforatus (Speiser) (♂) 60M. platytarsis Curran syn. nov. (♂) 61M. regulus (Hull) (♂) 62M. rex Curran (♂) 63M. senegalensis (Macquart) (♂).
Figures 64-69 from: Jordaens K, Goergen G, Skevington JH, Kelso S, De Meyer M (2021) Revision of the Afrotropical species of the hover fly genus Mesembrius Rondani (Diptera, Syrphidae) using morphological and molecular data. ZooKeys 1046: 1-141. https://doi.org/10.3897/zookeys.1046.57052
Figures 64-69 Mesembrius spp., head, frontal view 64M. simplicipes Curran (♂) 65M. strigilatus (Bezzi) (♂) 66M. sulcus sp. nov. (♂) 67M. tarsatus (Bigot) (♂) 68M. tibialis sp. nov. (♂) 69M. vockerothi sp. nov. (♂).
Figures 89-94 from: Jordaens K, Goergen G, Skevington JH, Kelso S, De Meyer M (2021) Revision of the Afrotropical species of the hover fly genus Mesembrius Rondani (Diptera, Syrphidae) using morphological and molecular data. ZooKeys 1046: 1-141. https://doi.org/10.3897/zookeys.1046.57052
Figures 89-94 Mesembrius spp., abdomen, dorsal view 89M. copelandi sp. nov. (♂) 90M. cyanipennis (Bezzi) (♂) 91M. ingratus (Loew) (♂) 92M. longipilosus sp. nov. (♂) 93M. madagascariensis Keiser (♂) 94M. minor (Bezzi) (♂).
FIGURES 4-6 in Description of two new species of Rhamphus related to R. oxyacanthae (Curculionidae, Curculioninae, Rhamphini) from Italy based on a morphological study supported by molecular data
FIGURES 4-6. Dorsal habitus of (4) Rhamphus oxyacanthae; (5) R. hampsicora; (6) R. monzinii.
Data from: Reporting tumor molecular heterogeneity in histopathological diagnosis
Background: Detection of molecular tumor heterogeneity has become of paramount importance with the advent of targeted therapies. Analysis for detection should be comprehensive, timely and based on routinely available tumor samples. Aim: To evaluate the diagnostic potential of targeted multigene next-generation sequencing (TM-NGS) in characterizing gastrointestinal cancer molecular heterogeneity. Methods: 35 gastrointestinal tract tumors, five of each intestinal type gastric carcinomas, pancreatic ductal adenocarcinomas, pancreatic intraductal papillary mucinous neoplasms, ampulla of Vater carcinomas, hepatocellular carcinomas, cholangiocarcinomas, pancreatic solid pseudopapillary tumors were assessed for mutations in 46 cancer-associated genes, using Ion Torrent semiconductor-based TM-NGS. One ampulla of Vater carcinoma cell line and one hepatic carcinosarcoma served to assess assay sensitivity. TP53, PIK3CA, KRAS, and BRAF mutations were validated by conventional Sanger sequencing. Results: TM-NGS yielded overlapping results on matched fresh-frozen and formalin-fixed paraffin-embedded (FFPE) tissues, with a mutation detection limit of 1% for fresh-frozen high molecular weight DNA and 2% for FFPE partially degraded DNA. At least one somatic mutation was observed in all tumors tested; multiple alterations were detected in 20/35 (57%) tumors. Seven cancers displayed significant differences in allelic frequencies for distinct mutations, indicating the presence of intratumor molecular heterogeneity; this was confirmed on selected samples by immunohistochemistry of p53 and Smad4, showing concordance with mutational analysis. Conclusions: TM-NGS is able to detect and quantitate multiple gene alterations from limited amounts of DNA, moving one step closer to a next-generation histopathologic diagnosis that integrates morphologic, immunophenotypic, and multigene mutational analysis on routinely processed tissues, essential for personalized cancer therapy.
Data from: Resequencing of common bean identifies regions of inter-gene pool introgression and provides comprehensive resources for molecular breeding
Common bean is the most important grain legume for human consumption and a main nutrition source in the tropics. Because bean production is reduced by both abiotic and biotic constraints, current breeding efforts are focused on the development of improved varieties with tolerance to these stresses. We characterized materials from different breeding programs spanning three continents to understand their sequence diversity and advance the development of molecular breeding tools. For this, 37 varieties belonging to P. vulgaris, P. acutifolius, and P. coccineus were sequenced by whole-genome sequencing (WGS), identifying more than 40 million genomic variants. Evaluation of nuclear DNA content and analysis of copy number variation revealed important differences in genomic content not only between P. vulgaris and two other domesticated Phaseolus species, but also within P. vulgaris, affecting hundreds of protein-coding genomic regions. A large number of inter-gene-pool introgressions were identified. Furthermore, interspecific introgressions for disease resistance in breeding lines were mapped. Evaluation of newly developed SNP markers within previously discovered QTL for common bacterial blight and angular leaf spot provide improved specificity to tag sources of resistance to these diseases. We expect that this dataset will provide a deeper molecular understanding of breeding germplasm and deliver molecular tools for germplasm development, aiming to increase the efficiency of bean breeding programs.
Data from: Phosphorylated Groucho delays differentiation in the follicle stem cell lineage by providing a molecular memory of EGFR signaling in the niche
In the epithelial follicle stem cells (FSCs) of the Drosophila ovary, Epidermal Growth Factor Receptor (EGFR) signaling promotes self-renewal, whereas Notch signaling promotes differentiation of the prefollicle cell (pFC) daughters. We have identified two proteins, Six4 and Groucho (Gro), that link the activity of these two pathways to regulate the earliest cell fate decision in the FSC lineage. Our data indicate that Six4 and Gro promote differentiation towards the polar cell fate by promoting Notch pathway activity. This activity of Gro is antagonized by EGFR signaling, which inhibits Gro-dependent repression via p-ERK mediated phosphorylation. We have found that the phosphorylated form of Gro persists in newly formed pFCs, which may delay differentiation and provide these cells with a temporary memory of the EGFR signal. Collectively, these findings demonstrate that phosphorylated Gro labels a transition state in the FSC lineage and describe the interplay between Notch and EGFR signaling that governs the differentiation processes during this period.
FIGURES 7 in Molecular relationships of the Australian Ennominae (Lepidoptera: Geometridae) and implications for the phylogeny of the Geometridae from molecular and morphological data
FIGURES 7. Two dimensional structure of a 28S D2 gene fragment for Monoctenia falernaria.
FIGURES 8 in Molecular relationships of the Australian Ennominae (Lepidoptera: Geometridae) and implications for the phylogeny of the Geometridae from molecular and morphological data
FIGURES 8. Two dimensional structure of a 28S D2 gene fragment for Palleopa innotata.
FIGURES 6 in Molecular relationships of the Australian Ennominae (Lepidoptera: Geometridae) and implications for the phylogeny of the Geometridae from molecular and morphological data
FIGURES 6. Two dimensional structure of a 28S D2 gene fragment for Archiearis parthenias.
FIGURES 5 in Molecular relationships of the Australian Ennominae (Lepidoptera: Geometridae) and implications for the phylogeny of the Geometridae from molecular and morphological data
FIGURES 5. Two dimensional structure of a 28S D2 gene fragment for Alsophila aescularia.
FIGURE 22 in A revision of the Trimeresurus puniceus-complex (Serpentes: Viperidae: Crotalinae) based on morphological and molecular data
FIGURE 22. Trimeresurus wiroti. Hemipenes. Photograph by Lawan Chanhome.
FIGURE 29. Trimeresurus brongersmai. Holotype, RMNH 5654A in A revision of the Trimeresurus puniceus-complex (Serpentes: Viperidae: Crotalinae) based on morphological and molecular data
FIGURE 29. Trimeresurus brongersmai. Holotype, RMNH 5654A. General view. Photograph by Roger Bour.
FIGURE 15. Trimeresurus borneensis. Syntype, ZMB 7146 in A revision of the Trimeresurus puniceus-complex (Serpentes: Viperidae: Crotalinae) based on morphological and molecular data
FIGURE 15. Trimeresurus borneensis. Syntype, ZMB 7146. General view. Photograph by Gernot Vogel.
FIGURE 11 in A revision of the Trimeresurus puniceus-complex (Serpentes: Viperidae: Crotalinae) based on morphological and molecular data
FIGURE 11. Trimeresurus puniceus. Living female, from Sumatra. Photograph by Albert Halimi.
FIGURE 9 in A revision of the Trimeresurus puniceus-complex (Serpentes: Viperidae: Crotalinae) based on morphological and molecular data
FIGURE 9. Trimeresurus puniceus. Living female, from Java. Photograph by Gernot Vogel.
FIGURE 7 in A revision of the Trimeresurus puniceus-complex (Serpentes: Viperidae: Crotalinae) based on morphological and molecular data
FIGURE 7. Trimeresurus puniceus. Living male, from Java. Photograph by Rick Hodges.
FIGURE 10 in A revision of the Trimeresurus puniceus-complex (Serpentes: Viperidae: Crotalinae) based on morphological and molecular data
FIGURE 10. Trimeresurus puniceus. Living male, from Sumatra. Photograph by Albert Halimi.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.