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402
datasets available to search
ShareScore release 0.9.0
Dataset results
402 results for “MtDNA”
Next generation sequencing reveals no change in mtDNA deletions upon the loss of mitochondrial fusion in mouse hearts
GEO Series GSE124420. Mus musculus. 7 samples. Type: Other.
PNPase knockout results in mtDNA loss and an altered metabolic gene expression program
GEO Series GSE111668. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Thymidine Kinase and mtDNA Depletion in Human Cardiomyopathy: Epigentic and Translational Evidence for Energy Starvation
GEO Series GSE43435. Homo sapiens. 40 samples. Type: Expression profiling by array; Methylation profiling by genome tiling array.
mtDNA breaks compromise mitochondrial membrane ultrastructure and trigger an integrated stress response
GEO Series GSE214512. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide analysis of gene expression patterns by osteosarcoma tumor cells with different mtDNA genotypes
GEO Series GSE73120. Homo sapiens. 17 samples. Type: Expression profiling by array.
Arf1-deficiency-induced neuronal surplus fatty acid synthesis evokes neurodegeneration through mtDNA releasing and inflammatory activating in microglia
GEO Series GSE273284. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
mtDNA sequencing of aged muscle stem cells (mouse)
GEO Series GSE180953. Mus musculus. 20 samples. Type: Genome variation profiling by high throughput sequencing.
Regulators of mitonuclear balance link mitochondrial metabolism to mtDNA expression
GEO Series GSE240576. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing; Other.
Effect of depletion of C17orf80 on mtDNA transcription in HEK-293T cells
GEO Series GSE224121. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
Regulators of mitonuclear balance link mitochondrial metabolism to mtDNA expression
GEO Series GSE224818. Homo sapiens. 14 samples. Type: Other.
Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for precise termination of mtDNA replication
GEO Series GSE199771. Mus musculus. 8 samples. Type: Other.
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI).
GEO Series GSE104105. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Data from: Global mtDNA genetic structure and hypothesized invasion history of a major pest of citrus, Diaphorina citri (Hemiptera: Liviidae)
The Asian citrus psyllid Diaphorina citri Kuwayama, is a key pest of citrus as the vector of the bacterium causing the 'huanglongbing' disease (HLB). To assess the global mtDNA population genetic structure, and possible dispersal history of the pest, we investigated genetic variation at the COI gene collating newly collected samples with all previously published data. Our dataset consists of 356 colonies from 106 geographic sites worldwide. High haplotype diversity (H-mean = 0.702 ± 0.017), low nucleotide diversity (π-mean = 0.003), and significant positive selection (Ka/Ks = 32.92) were observed. Forty-four haplotypes (Hap) were identified, clustered into two matrilines: Both occur in southeastern and southern Asia, North and South America, and Africa; Lineages A and B also occur in eastern and western Asia, respectively. The most abundant haplotypes were Hap4 in lineage A (35.67%), and Hap9 in lineage B (41.29%). The haplotype network identified them as the ancestral haplotypes within their respective lineages. Analysis of molecular variance showed significant genetic structure (FST = 0.62, p < 0.0001) between the lineages, and population genetic analysis suggests geographic structuring. We hypothesize a southern and/or southeastern Asia origin, three dispersal routes, and parallel expansions of two lineages. The hypothesized first route involved the expansion of lineage B from southern Asia into North America via West Asia. The second, the expansion of some lineage A individuals from Southeast Asia into East Asia, and the third involved both lineages from Southeast Asia spreading westward into Africa and subsequently into South America. To test these hypotheses and gain a deeper understanding of the global history of D. citri more data-rich approaches will be necessary from the ample toolkit of next generation sequencing (NGS). However, the current paper may serve to guide such sampling and in the development of biological control programs against the global pest D. citri.
Data from: Influence of alignment on the mtDNA phylogeny of Cetacea: questionable support for a Mysticeti/Physeteroidea clade
[No abstract entered]
Data from: Obtaining mtDNA genomes from next-generation transcriptome sequencing: a case study on the basal Passerida (Aves: Passeriformes) phylogeny.
Classically, the mitochondrial genome is sequenced by a series of amplicons using conserved PCR primers. Here we show how shot-gun transcriptome sequencing can be used to obtain the complete set of protein-coding genes from the mtDNA of four passerine bird species. With these sequences, we address the still unresolved basal Passerida relationships (Aves: Passeriformes). Our analysis suggests a new hypothesis for the basal relationships of Passerida, namely a clade grouping Sylvioidea and Passeroidea, with Paridae and Muscicapidae as successive sister groups to this clade. This study demonstrates the usefulness of next-generation sequencing transcriptome sequencing for obtaining new mtDNA genomes.
Figure 1 from: Basibuyuk H, Budak M, Korkmaz E (2011) A molecular phylogeny of the Cephinae (Hymenoptera, Cephidae) based on mtDNA COI gene: a test of traditional classification. ZooKeys 130: 363-378. https://doi.org/10.3897/zookeys.130.1466
Figure 1 - Percentage of nucleotide composition at each codon position.
Figure 4 from: Stahls G, Haarto A (2014) When mtDNA COI is misleading: congruent signal of ITS2 molecular marker and morphology for North European Melanostoma Schiner, 1860 (Diptera, Syrphidae). ZooKeys 431: 93-134. https://doi.org/10.3897/zookeys.431.7207
Figure 4 - Antenna. A Melanostoma scalare, male and B Melanostoma certum, male.
Figure 16 from: Stahls G, Haarto A (2014) When mtDNA COI is misleading: congruent signal of ITS2 molecular marker and morphology for North European Melanostoma Schiner, 1860 (Diptera, Syrphidae). ZooKeys 431: 93-134. https://doi.org/10.3897/zookeys.431.7207
Figure 16 - Lateral view of male scutum. A Melanostoma mellinum and B Melanostoma certum.
Figure 15 from: Stahls G, Haarto A (2014) When mtDNA COI is misleading: congruent signal of ITS2 molecular marker and morphology for North European Melanostoma Schiner, 1860 (Diptera, Syrphidae). ZooKeys 431: 93-134. https://doi.org/10.3897/zookeys.431.7207
Figure 15 - Frons of female. A Melanostoma mellinum and B Melanostoma certum.
Figure 1 from: Stahls G, Haarto A (2014) When mtDNA COI is misleading: congruent signal of ITS2 molecular marker and morphology for North European Melanostoma Schiner, 1860 (Diptera, Syrphidae). ZooKeys 431: 93-134. https://doi.org/10.3897/zookeys.431.7207
Figure 1 - Shape of metasternum. A Melanostoma mellarium and B Platycheirus podagratus.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.