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316
datasets available to search
ShareScore release 0.9.0
Dataset results
316 results for “drug target”
Antihistamine Drug Ebastine inhibits cancer growth by targeting Polycomb Group Protein EZH2
GEO Series GSE153652. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Integrated transcriptomic and in silico drug screening identifies potential stroma-targeting therapeutics in pancreatic cancer
GEO Series GSE196524. Homo sapiens. 48 samples. Type: Expression profiling by array.
Effects of halogenated boroxine on expression of human cancer drug targets in melanoma cell line
GEO Series GSE81278. Homo sapiens. 3 samples. Type: Expression profiling by RT-PCR.
Systematic characterization of LUHMES cell-based Parkinson’s disease models reveals potential novel drug targets.
GEO Series GSE287941. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
Telomerase-mediated Strategy for Overcoming Non-Small Cell Lung Cancer Targeted Therapy and Multi-drug Chemotherapy Resistance
GEO Series GSE109821. Homo sapiens. 54 samples. Type: Expression profiling by high throughput sequencing.
Inhibition of nucleotide biosynthesis to enhance responses to drugs targeting androgen biosynthesis and the androgen receptor
GEO Series GSE142196. Homo sapiens. 47 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
miR-106b-5p is a key player in adaptive response to drug-induced liver injury and liver regeneration by targeting vimentin
GEO Series GSE160961. Mus musculus. 24 samples. Type: Non-coding RNA profiling by array.
Therapeutic efficacy of antimalarial drugs targeting DosRS signaling in Mycobacterium abscessus
GEO Series GSE174310. Mycobacteroides abscessus ATCC 19977. 8 samples. Type: Expression profiling by high throughput sequencing.
Enhancing Tumor Targeting of Antitumor Drugs through Anlotinib-Mediated Modulation of Extracellular Matrix and RhoA/ROCK Signaling Pathway
GEO Series GSE237818. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Differential KEAP1/NRF2-mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy [array]
GEO Series GSE280642. Homo sapiens. 24 samples. Type: Expression profiling by array.
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets
GEO Series GSE120746. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
A cell competition-based drug screen identifies a novel compound that targets c-Myc addiction of leukemia cells
GEO Series GSE100678. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profiling of a patient-matched cohort of glioblastoma (IDH-wildtype) for therapeutic target and repurposing drug identification
GEO Series GSE212067. Homo sapiens. 18 samples. Type: Expression profiling by array.
New Strategy for the Development of Targeted Drug Delivery Systems in Cancer Therapy
<p>Rare dataset of the experiments performed during the investigation of our newly developed SREKA pentapeptide, and its use for liposome preparation.</p>
Datasets for training and for testing ligand-based reverse screening to predict drug targets.
<p>Bioactivity data were obtained from the ChEMBL (version 25) and the Reaxys<sup>®</sup> (version 03.2019) databases for training/screening and testing target prediction of small molecule drug by reverse screening. A short extract of the raw ChEMBL data for training is given in <strong>Supplementary Table 1 </strong>(Supp_Table_1.xlsx) to show three lines corresponding to an active, an inactive and an ‘gray area’ datapoints, respectively. Processed data are deposited here. The screening set file contains (CHEMBL-screeningset.csv), for each active compound, the standardized SMILES, the ChEMBLID, the number of experimental target(s) and their UniProt identifier(s). The test set file (Reaxys-testset-with300-SMILES.csv) contains, for each 364201 active compound, the ReaxysID, the number of experimental target(s) and the UniProt identifier(s). For Reaxys users, the chemical structure can be obtained through bulk request on the website. Access to www.reaxys.com and to Reaxys data can be obtained by contacting Elsevier directly. The first 300 entries display the standardized SMILES so that every reader can reproduce the results obtained by the reverse screening exercise.</p> <p>Further datasets can be obtained at www.swisstargetprediction.ch/download.php</p>
The targeted genes of KIF11 of PLC8024 cell after drug treatment
GEO Series GSE294035. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.