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3,264
datasets available to search
ShareScore release 0.9.0
Dataset results
3,264 results for “FAST”
Transcriptome analysis of the barley fast neutron mutants nec3
GEO Series GSE23775. Hordeum vulgare. 6 samples. Type: Expression profiling by array.
Liver X receptor controls a bifurcated transcriptional program where lipogenesis genes overshoot upon refeeding while cholesterol biosynthesis genes return to pre-fasting levels [lxr_rna]
GEO Series GSE243054. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Liver X receptor controls a bifurcated transcriptional program where lipogenesis genes overshoot upon refeeding while cholesterol biosynthesis genes return to pre-fasting levels [kinetics_rna]
GEO Series GSE243049. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Long-term intermittent fasting restores function of the gut–liver axis and prevents development of diabetic retinopathy in db/db mice
GEO Series GSE100230. Mus musculus. 18 samples. Type: Expression profiling by array.
Liver X receptor controls a bifurcated transcriptional program where lipogenesis genes overshoot upon refeeding while cholesterol biosynthesis genes return to pre-fasting levels [lxr_chip]
GEO Series GSE243051. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Modulation of the post meal PBMC transcriptomic response of shift workers after four weeks of a dietary intervention implementing a dedicated overnight fast
GEO Series GSE225493. Homo sapiens. 113 samples. Type: Expression profiling by high throughput sequencing.
Effect of fasting and ketogenic diet on hippocampal astrocytes in vivo
GEO Series GSE169625. Mus musculus. 11 samples. Type: Expression profiling by array.
Sexually dimorphic effects of CYP2B6 in the development of fasting-mediated steatosis in mice: Effects are not mediated by the oxylipin products 9-HODE and 9-HOTrE
GEO Series GSE282292. Mus musculus. 44 samples. Type: Expression profiling by high throughput sequencing.
Next-generation sequencing facilitates quantitative analysis of rat BMSCs in fast, medium or slow stress relaxation SA hydrogel
GEO Series GSE186726. Rattus norvegicus. 9 samples. Type: Expression profiling by high throughput sequencing.
Rat liver: Caloric Restriction vs. Fasting vs. COntrol
GEO Series GSE9042. Rattus norvegicus; Homo sapiens. 60 samples. Type: Expression profiling by array.
Chromatin Remodeler RSC2 Modulates Binding of the Transcriptional Activator Ace1p and Improves the Transcription of CUP1 by Fast Cycles of Remodeling
GEO Series GSE112685. Saccharomyces cerevisiae. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
RNAseq analysis for Fast Generated Functional Subtype Astrocytes from Human Pluripotent Stem Cells
GEO Series GSE118384. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster.
GEO Series GSE47631. Drosophila melanogaster. 38 samples. Type: Expression profiling by array.
Intermittent fasting reduces alpha-synuclein pathology and functional decline in a mouse model of Parkinson’s disease
GEO Series GSE252874. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Fast evolution of gained essential function by a young gene through gained interaction with other essential genes [ChIP-Seq]
GEO Series GSE100342. Drosophila melanogaster. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Comparison of hepatic gene expression in response to fasting or 2 week high fat diet
GEO Series GSE8576. Mus musculus. 28 samples. Type: Expression profiling by array.
Data for "A Fast-Charging Study on the Lifetime of Power-Optimized Lithium Titanite Batteries By Electrochemical Impedance Spectroscopy"
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Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease
<p>These databases are from the pilot clinical trial, Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease. This study determined the feasibility of delivering two behavioral weight loss interventions for 1 year in adults with autosomal dominant polycystic kidney disease (ADPKD) who were overweight or obese. The study also compared these two interventions in terms of safety, acceptability, and tolerability. Last, the trial will provided initial insight into a) biological changes and b) changes in kidney growth with each of the two weight loss interventions. The main data are provided as a SAS files (with data dictionaries), with adherence data as a SPSS file. The data are available to qualified individuals within the scientific community who apply for data use directly with the lead contact. </p>
Fast, streamlined fluorescence nanoscopy resolves rearrangements of SNARE and cargo proteins in platelets co-incubated with cancer cells.
<p><strong>This folder contains all raw data underlying the results presented in a manuscript, submitted to </strong><strong><em>Journal of Nanobiotechnology</em></strong><strong>, and entitled:</strong></p> <p> </p> <p><strong>Fast, streamlined fluorescence nanoscopy resolves rearrangements of SNARE and cargo proteins in platelets co-incubated with cancer cells.</strong></p> <p> </p> <p><strong>Authored by:</strong></p> <p>Jan Bergstrand<sup>a,+</sup>, Xinyan Miao<sup>a,+</sup>, Chinmaya Venugopal Srambickal<sup>a,+</sup>, Gert Auer<sup>b</sup>, Jerker Widengren<sup>a,*</sup></p> <p><sup>a</sup> Royal Institute of Technology (KTH), Department of Applied Physics, Experimental Biomolecular Physics, Albanova Univ Center, SE-106 91 Stockholm, Sweden</p> <p><sup>b</sup> Karolinska Institutet, Department of Oncology-Pathology, K7, Z1:00, Karolinska University Hospital, 171 76 Stockholm, Sweden</p> <p><sup>* </sup>To whom correspondence should be addressed. E-mail: <a href="mailto:jwideng@kth.se">jwideng@kth.se</a>, Phone: +46-8-7907813</p> <p><sup>+ </sup>These authors contributed equally</p> <p> </p> <p><strong>The data files are grouped into the different </strong><strong>figures where they are presented</strong><strong>.</strong></p> <p> </p> <p><strong>ABSTRACT</strong></p> <p>Background:</p> <p>Increasing evidence suggests that platelets play a central role in cancer progression, with altered storage and selective release from platelets of specific tumor-promoting proteins as a major mechanism. Fluorescence-based super-resolution microscopy (SRM) can resolve nanoscale spatial distribution patterns of such proteins, and how they are altered in platelets upon different activations. Analysing such alterations by SRM thus represents a promising, minimally invasive strategy for platelet-based diagnosis and monitoring of cancer progression. However, broader applicability beyond specialized research labs will require objective, more automated imaging procedures. Moreover, for statistically significant analyses many SRM platelet images are needed, of several different platelet proteins. Such proteins, showing alterations in their distributions upon cancer progression additionally need to be identified.</p> <p>Results:</p> <p>A fast, streamlined and objective procedure for SRM platelet image acquisition, analysis and classification was developed to overcome these limitations. By stimulated emission depletion SRM we imaged nanoscale patterns of six different platelet proteins; four different SNAREs (soluble N-ethylmaleimide factor attachment protein receptors) mediating protein secretion by membrane fusion of storage granules, and two angiogenesis regulating proteins, representing cargo proteins within these granules coupled to tumor progression. By an streamlined procedure, we recorded about 100 SRM images of platelets, for each of these six proteins, and for five different categories of platelets; incubated with cancer cells (MCF-7, MDA-MB-231, EFO-21), non-cancer cells (MCF-10A), or no cells at all. From these images, structural similarity and protein cluster parameters were determined, and probability functions of these parameters were generated for the different platelet categories. By comparing these probability functions between the categories, we could identify nanoscale alterations in the protein distributions, allowing us to classify the platelets into their correct categories, if they were co-incubated with cancer cells, non-cancer cells, or no cells at all.</p> <p>Conclusions:</p> <p>The fast, streamlined and objective acquisition and analysis procedure established in this work confirms the role of SNAREs and angiogenesis-regulating proteins in platelet-mediated cancer progression, provides additional fundamental knowledge on the interplay between tumor cells and platelets, and represent an important step towards using tumor-platelet interactions and redistribution of nanoscale protein patterns in platelets as a basis for cancer diagnostics.</p> <p> </p> <p><strong>Key Words:</strong></p> <p>STED, super-resolution microscopy, platelet, cancer, tumorigenesis, SNARE protein, dictionary learning</p>
intermittent fasting
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.