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3,458 results for “Chromosomes”
"The evolutionary history of Neandertal and Denisovan Y chromosomes" - Y chromosome capture designs
<p>Coordinates of target capture regions and sequences of capture probes used in the paper "The evolutionary history of Neandertal and Denisovan Y chromosomes" by Petr et al. See the project's GitHub repository for more information: <a href="https://www.github.com/bodkan/archaic-ychr">https://www.github.com/bodkan/archaic-ychr</a>.</p>
in the heterochromatic segment of the short arm in Comparative chromosomal studies in Rhinolophus formosae and R. luctus from China and Vietnam: elevation of R. l. lanosus to species rank
in the heterochromatic segment of the short arm
F — chromosome 1 in Comparative chromosomal studies in Rhinolophus formosae and R. luctus from China and Vietnam: elevation of R. l. lanosus to species rank
F — chromosome 1 of R. formosae showed homology to AST1 (green) and AST12 (red)
indicate the active NORs on pair 8 in Comparative chromosomal studies in Rhinolophus formosae and R. luctus from China and Vietnam: elevation of R. l. lanosus to species rank
indicate the active NORs on pair 8
FIGURE 1 in A new species of Synotaxus and the first chromosomal study on Synotaxidae, presenting a rare XY sex chromosome system in spiders (Araneae, Araneoidea)
FIGURE 1. Female specimen of Synotaxus jaraguari n. sp., dorsal view. Scale bar, 4 mm.
Link to dataset related to article "X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis"
<p>Link to dataset related to article "X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis"</p> <p>Abstract</p> <p><strong>Background & aims: </strong> Genome-wide association studies in primary biliary cholangitis (PBC) have failed to find X chromosome (chrX) variants associated with the disease. Here, we specifically explore the chrX contribution to PBC, a sexually dimorphic complex autoimmune disease.</p> <p><strong>Methods: </strong> We performed a chrX-wide association study, including genotype data from 5 genome-wide association studies (from Italy, United Kingdom, Canada, China, and Japan; 5244 case patients and 11,875 control individuals).</p> <p><strong>Results: </strong> Single-marker association analyses found approximately 100 loci displaying P < 5 × 10<sup>-4</sup>, with the most significant being a signal within the OTUD5 gene (rs3027490; P = 4.80 × 10<sup>-6</sup>; odds ratio [OR], 1.39; 95% confidence interval [CI], 1.028-1.88; Japanese cohort). Although the transethnic meta-analysis evidenced only a suggestive signal (rs2239452, mapping within the PIM2 gene; OR, 1.17; 95% CI, 1.09-1.26; P = 9.93 × 10<sup>-8</sup>), the population-specific meta-analysis showed a genome-wide significant locus in East Asian individuals pointing to the same region (rs7059064, mapping within the GRIPAP1 gene; P = 6.2 × 10<sup>-9</sup>; OR, 1.33; 95% CI, 1.21-1.46). Indeed, rs7059064 tags a unique linkage disequilibrium block including 7 genes: TIMM17B, PQBP1, PIM2, SLC35A2, OTUD5, KCND1, and GRIPAP1, as well as a superenhancer (GH0XJ048933 within OTUD5) targeting all these genes. GH0XJ048933 is also predicted to target FOXP3, the main T-regulatory cell lineage specification factor. Consistently, OTUD5 and FOXP3 RNA levels were up-regulated in PBC case patients (1.75- and 1.64-fold, respectively).</p> <p><strong>Conclusions: </strong> This work represents the first comprehensive study, to our knowledge, of the chrX contribution to the genetics of an autoimmune liver disease and shows a novel PBC-related genome-wide significant locus.</p>
Fig. 2 in Review of the Plangia graminea (Serville) complex and the description of new Plangia species from East Africa (Orthoptera: Phaneropteridae, Phaneropterinae) with data on habitat, bioacoustics, and chromosomes
Fig. 2 Plangia graminea, Port Elisabeth, South Africa (NMW)
Fig. 14 in Review of the Plangia graminea (Serville) complex and the description of new Plangia species from East Africa (Orthoptera: Phaneropteridae, Phaneropterinae) with data on habitat, bioacoustics, and chromosomes
Fig. 14 Power spectra of the calling song of Plangia species (female examined only up to 22 kHz)
Fig. 12 in Ecology, acoustics and chromosomes of the East African genus Afroanthracites Hemp & Ingrisch (Orthoptera, Tettigoniidae, Conocephalinae, Agraeciini) with the description of new species
Fig. 12 Oscillograms of calling songs of Afroanthracites species and Afroagraecia brachyptera
Fig. 4 a,b in The genus Aerotegmina (Orthoptera, Tettigoniidae, Hexacentrinae): chromosomes, morphological relations, phylogeographical patterns and description of a new species
Fig. 4 a,b Dorsal aspect of male Aerotegmina alae. a A. kilimandjarica. b A. taitensis
Fig. 6 in The genus Aerotegmina (Orthoptera, Tettigoniidae, Hexacentrinae): chromosomes, morphological relations, phylogeographical patterns and description of a new species
Fig. 6 Oscillograms of calling songs of Aerotegmina species and the phaneropterine Euryastes jagoi
Fig. 2 Lunidia viridis n. gen. n in A new genus and species of African Phaneropterinae (Orthoptera: Tettigoniidae), with data on its ecology, bioacoustics and chromosomes
Fig. 2 Lunidia viridis n. gen. n. sp., male; note silvery and red tracheal openings and large cerci
Fig. 8 Lunidia viridis n. gen. n in A new genus and species of African Phaneropterinae (Orthoptera: Tettigoniidae), with data on its ecology, bioacoustics and chromosomes
Fig. 8 Lunidia viridis n. gen. n. sp., spectrum of calling song as recorded with Pettersson D1000X
Nuclear Genome Organization in Fungi: From Gene folding to Rabl Chromosomes
<p>We discuss the current knowledge on the fungal genome organization, from the association of chromosomes within the nucleus to topological structures at individual genes and the genetic factors required for the hierarchical organization. Chromosome conformation capture followed by high-throughput sequencing (Hi-C) has elucidated how fungal genomes are globally organized in Rabl configuration where centromere or telomere bundles are associated with opposite faces of the nuclear envelope. Here, we explore the presence, in fungal taxa, of the typical proteins associated with genome organization in eukaryotes.</p>
Nuclear Genome Organization in Fungi: From Gene folding to Rabl Chromosomes
<p>We discuss the current knowledge on the fungal genome organization, from the association of chromosomes within the nucleus to topological structures at individual genes and the genetic factors required for the hierarchical organization. Chromosome conformation capture followed by high-throughput sequencing (Hi-C) has elucidated how fungal genomes are globally organized in Rabl configuration where centromere or telomere bundles are associated with opposite faces of the nuclear envelope. Here, we explore the presence, in fungal taxa, of the typical proteins associated with genome organization in eukaryotes.</p>
MAP to Provide Access to Nilotinib, for Patients With Relapsed or Refractory Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
ClinicalTrials.gov study NCT04559555. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Study for Safety and Efficacy Evaluation of Imatinib Mesylate in Children With Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)
ClinicalTrials.gov study NCT01222013. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Chromosomal integrons are genetically and functionally isolated units of genomes
GEO Series GSE247496. Vibrio cholerae. 12 samples. Type: Expression profiling by high throughput sequencing.
Genetic correlates in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with Hyper-CVAD plus dasatinib or ponatinib
GEO Series GSE190395. Homo sapiens. 95 samples. Type: Genome variation profiling by high throughput sequencing.
Chromosome conformation capture of Jurkat T cells during parabolic flight
GEO Series GSE174291. Homo sapiens. 12 samples. Type: Other.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.