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3,693 results for “cardiovascular”
Table A6 images from Computer-aided drug design (CADD) to de-orphanise marine molecules: Finding potential therapeutic agents for neurodegenerative and cardiovascular diseases
<p>High Reslution Images from Table A6</p>
AUMENTO DEL RIESGO CARDIOVASCULAR EN PACIENTES CON APNEA OBSTRUCTIVA DEL SUEÑO
<p>En Colombia la prevalencia de los trastornos del sueño, constituyen un problema de salud pública, La apnea obstructiva del sueño (AOS) es causada por el colapso de la vía aérea superior durante la inspiración y se acompaña de esfuerzos de respiración extenuantes. La hipoxemia acompañada de re oxigenación, activa los genes del sistema reducción-oxidación, síntesis de mediadores inflamatorios, vasoconstrictores, produciendo incremento en la actividad simpática y causando estrés oxidativo, aumentando el riesgo cardiovascular</p>
Incident Cardiovascular Data
Open the record for dataset details and reuse information.
Xylitol is associated with cardiovascular event risks and enhances platelet responsiveness and thrombosis potential in vivo
Open the record for dataset details and reuse information.
Supplemental Tables for "The Impact of hypothyroidism on cardiovascular-related healthcare utilization in the US population with diabetes
<p>Supplemental tables for publication in the Journal of the Endocrine Society</p>
Data from: Conflicts at work are associated with a higher risk of cardiovascular disease
Background: Only few authors have analyzed the impact of workplace conflicts and the resulting stress on the risk of developing cardiovascular disorders. The goal of this study was to analyze the association between workplace conflicts and cardiovascular disorders in patients treated by German general practitioners. Methods: Patients with an initial documentation of a workplace conflict experience between 2005 and 2014 were identified in 699 general practitioner practices (index date). We included only those that were between the ages of 18 and 65 years, had a follow-up time of at least 180 days after the index date, and had not been diagnosed with angina pectoris, myocardial infarction, coronary heart diseases, or stroke prior to the documentation of the workplace mobbing. In total, this study consisted of 7,374 patients who experienced conflicts and 7,374 controls for analysis. The main outcome measure was the incidence of angina pectoris, myocardial infarction, and stroke correlated with workplace conflict experiences. Results: After a maximum of five years of follow-up, 2.9% of individuals who experienced workplace conflict were affected by cardiovascular diseases, while only 1.4% were affected in the control group (p-value<0.001). Workplace conflict was associated with a 1.63-fold increase in the risk of developing cardiovascular diseases. Finally, the impact of workplace conflict was higher for myocardial infarction (OR=2.03) than for angina pectoris (OR=1.79) and stroke (OR=1.56). Conclusions: Overall, we found a significant association between workplace conflicts and cardiovascular disorders.
Evaluating the educational effectiveness of a structured, simulator-assisted, peer-led training on cardiovascular physical examination in third-year medical students: A randomized, controlled trial
<p class="AbstractCxSpFirst"><span><span><span><span><span><span><span><span><span><span><span><b>Background:</b> Previous research suggests that cardiac examination skills in undergraduate medical students frequently need improvement. There are different ways to enhance physical examination (PE) skills such as simulator-based training or peer-assisted learning (PAL). </span></span></span></span></span></span></span></span></span></span></span></p> <p class="AbstractCxSpMiddle"><span><span><span><span><span><span><span><span><span><span><span><b>Aim:</b> The aim of this study was to evaluate the effectiveness of a structured, simulator-assisted, peer-led training on cardiovascular PE.</span></span></span></span></span></span></span></span></span></span></span></p> <p class="AbstractCxSpMiddle"><span><span><span><span><span><span><span><span><span><span><span><b>Methods:</b> Participants were third-year medical students at Leipzig University Faculty of Medicine. Students were randomly assigned to an intervention group (IG) and a control group (CG). In addition to standard curricular training, IG received a peer-led, simulator-based training in cardiac PE. Participant performance in cardiac PE was assessed using a standardized checklist with a maximum of 25 points. Primary outcome was assessed via checklist point distribution.</span></span></span></span></span></span></span></span></span></span></span></p> <p class="AbstractCxSpMiddle"><span><span><span><span><span><span><span><span><span><span><span><b>Results:</b> 89 students were randomised to either CG (<i>n</i> = 43) or IG (<i>n</i> = 46) with 70 completing the study. Overall, IG students performed significantly better than CG students did (max. points: 25, IG M ± SD in IG was 17 ± 3, in CG 12 ± 4, p < .0001). Simple mistakes such as not using the stethoscope correctly were more frequent in CG students. Prior experience did not lead to a significant difference in performance. </span></span></span></span></span></span></span></span></span></span></span></p> <p class="Abstract"><span><span><span><span><span><span><span><span><span><span><span><b>Conclusions:</b> Structured, peer-led and simulator-assisted teaching sessions improve cardiac PE skills in this setting compared to control students that did not receive this training.</span></span></span></span></span></span></span></span></span></span></span></p>
Endothelial and leukocyte-derived microvesicles and cardiovascular risk after stroke: PROSCIS-B
<p><strong>Objective:</strong> To determine the role of circulating endothelial microvesicles (EMV) and microvesicles (MV) of other origins on long-term cardiovascular outcomes after stroke, we measured them in a cohort of first-ever stroke patients and observed them for three years.</p> <p><strong>Methods:</strong> In the PROSpective Cohort with Incident Stroke Berlin (PROSCIS-B), patients with first-ever ischemic stroke were followed for three years. The primary combined endpoint consisted of recurrent stroke, myocardial infarction, and all-cause mortality. Levels of EMV, leukocyte-derived MV (LMV), monocytic MV (MMV), and platelet-derived MV (PMV) were measured in citrate blood using flow cytometry. Kaplan-Meier curves and Cox proportional hazards models were used to estimate the effect of MV levels on the combined endpoint after adjustment confounding.</p> <p><strong>Results: </strong>571 patients were recruited (median age 69y; 39% female; median NIHSS 2, interquartile range 1-4). During the follow-up, 95 endpoints occurred. Patients with levels of EMV [adjusted hazard ratio (HR)=2.5, 95% confidence interval (CI) 1.2-4.9] or LMV (HR=3.1, 95%CI 1.4-6.8) in the highest quartile were more likely to experience an event than participants with lower levels using the lowest quartile as reference category. The association was less pronounced for PMV (HR=1.7, 95%CI 0.9-3.2) and absent for MMV (HR=1.1, 95%CI 0.6-1.8).</p> <p><strong>Conclusion:</strong> High levels of EMV and LMV after ischemic stroke were associated with worse cardiovascular outcome within three years. These results reinforce that endothelial dysfunction and vascular inflammation affect the long-term prognosis after stroke. EMV and LMV might play a potential role in risk prediction for stroke patients.</p>
Metabolic and Cardiovascular Effects of Armolipid Plus in Subjects With Metabolic Syndrome
ClinicalTrials.gov study NCT02295176. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction
ClinicalTrials.gov study NCT05307718. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
ClinicalTrials.gov study NCT06383390. IPD Sharing: YES. Countries: 27. Publications: 1.
Diet, Body Composition, Lifestyle and Cardiovascular Health of Healthy and Active Adults From Slovenia
ClinicalTrials.gov study NCT04379622. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Cardiovascular Risk Markers and Response to Statins After Kawasaki Disease
ClinicalTrials.gov study NCT00305201. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Effect of Amount and Type of Dietary Carbohydrates on Risk for Cardiovascular Heart Disease and Diabetes
ClinicalTrials.gov study NCT00608049. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Ruminant Trans Fats and the Risk of Cardiovascular Disease in Women
ClinicalTrials.gov study NCT00930137. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Early Specialized Cardiovascular Intervention Based on Impedance Cardiography in Locally Advanced Non-small Cell Lung Cancer Patients
ClinicalTrials.gov study NCT04980716. IPD Sharing: Not stated. Countries: 1. Publications: 25.
Simplified Cardiovascular Management Study
ClinicalTrials.gov study NCT01503814. IPD Sharing: Not stated. Countries: 2. Publications: 7.
Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition
ClinicalTrials.gov study NCT03533179. IPD Sharing: NO. Countries: 1. Publications: 9.
Diet, ExerCIse and carDiovascular hEalth (DECIDE) - Salt Reduction Strategies for the Elderly in Nursing Homes in China
ClinicalTrials.gov study NCT03290716. IPD Sharing: NO. Countries: 1. Publications: 6.
Integrating Hypertension and Cardiovascular Diseases Care Into Existing HIV Services Package in Botswana (InterCARE)
ClinicalTrials.gov study NCT05414526. IPD Sharing: NO. Countries: 1. Publications: 3.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.