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3,430
datasets available to search
ShareScore release 0.9.0
Dataset results
3,430 results for “PD”
DRG2 is required for cell surface localization of PD-L1 in melanoma cells and optimum response to anti-PD-1 immune checkpoint blockade [scRNA-seq]
GEO Series GSE231973. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
ACSL4-programmed sphingomyelin metabolism rejuvenates tumor-infiltrating T-cells to enhance the efficacy of anti-PD-1 immunotherapy
GEO Series GSE233204. Mus musculus. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Knockdown MSLN enhances anti-PD-1 therapy efficacy in high-grade serous ovarian cancer via modulating tumor microenvironment.
GEO Series GSE279226. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Anti-PD-L1 Lead-in Before MAPKi Combination Maximizes Anti-Tumor Efficacy and Immunity.
GEO Series GSE177902. Mus musculus. 49 samples. Type: Other; Expression profiling by high throughput sequencing.
Melanoma cell lines: generated from pre vs generated post anti-PD-1 therapy
GEO Series GSE299076. Homo sapiens. 2 samples. Type: Expression profiling by array.
Inhaled TLR9 Agonist Renders Lung Tumors Permissive to PD-1 Blockade Promoting Optimal CD4+ and CD8+ T cell Interplay
GEO Series GSE113987. Mus musculus. 20 samples. Type: Expression profiling by array.
Combinational targeting CCL7 and Flt3L to promote the expansion and infiltration of cDC1 in tumors enhances T cell activation and anti-PD-1 therapy [Dendritic Cell]
GEO Series GSE225126. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Synthetic lethal CRISPR screen identifies a cancer cell-intrinsic role of PD-L1 in regulation of vulnerability to ferroptosis.
GEO Series GSE270147. Homo sapiens. 5 samples. Type: Other; Genome binding/occupancy profiling by high throughput sequencing.
Disease-specific exhaustion features and PD-1 immunotherapy responsiveness of antigen-specific CD8+ T cells at single-cell resolution [scRNA-seq]
GEO Series GSE152618. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Combinational targeting CCL7 and Flt3L to promote the expansion and infiltration of cDC1 in tumors enhances T cell activation and anti-PD-1 therapy [CD8 T]
GEO Series GSE225163. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Gene Expression profile for the characterization of PD-L1 blockade in melanoma model
GEO Series GSE172239. Mus musculus. 90 samples. Type: Expression profiling by array.
Disease-specific exhaustion features and PD-1 immunotherapy responsiveness of antigen-specific CD8+ T cells at single-cell resolution
GEO Series GSE152628. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
DRG2 is required for cell surface localization of PD-L1 in melanoma cells and optimum response to anti-PD-1 immune checkpoint blockade
GEO Series GSE231974. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Database DYMUS-PD_Dagna_avenali
<p>In this paper, we reported DYMUS (Dysphagia in Multiple Sclerosis) and the EAT-10( Eating Assessment Tool) questionnaires score from patients and caregivers. DYMUS is composed by 10 items, all the answers are dichotomous, coded as 1 or 0, depending on the presence or absence of the event (range of score: 0–10; higher = worse). EAT-10 is a clinical scale used to document dysphagia symptoms severity in patients with swallowing disorders. EAT-10 includes 10 questions, each scored from 0 to 4 (“no problem” to “severe problem”); the total score is calculated by adding the scores of each question, with a higher score indicating higher self-perceived dysphagia severity. For the comparison of DYMUS with fiber-optic endoscopic evaluation (FEES), patients underwent the instrumental evaluation. Based on FEES findings, dysphagia severity was rated according to the Dysphagia Outcome Severity Scale (DOSS). This database includes the raw data of Hoehn & Yahr staging system, MDS-Unified Parkinson’s Disease Rating Scale part 3, disease duration and MMSE (Mini-Mental State Examination) of each patient.</p>
Dataset related to article "Chemotherapy after PD-1 inhibitors in relapsed/refractory Hodgkin lymphoma: Outcomes and clonal evolution dynamics"
<p>This record contains raw data related to article "Chemotherapy after PD-1 inhibitors in relapsed/refractory Hodgkin lymphoma: Outcomes and clonal evolution dynamics"</p> <p>Checkpoint inhibitors (CPIs) are routinely employed in relapsed/refractory classical Hodgkin lymphoma. Nonetheless, persistent long-term responses are uncommon, and one-third of patients are refractory. Several reports have suggested that treatment with CPIs may re-sensitize patients to chemotherapy, however there is no consensus on the optimal chemotherapy regimen and subsequent consolidation strategy. In this retrospective study we analysed the response to rechallenge with chemotherapy after CPI failure. Furthermore, we exploratively characterized the clonal evolution profile of a small sample of patients (n = 5) by employing the CALDER approach. Among the 28 patients included in the study, 17 (71%) were primary refractory and 26 (92%) were refractory to the last chemotherapy prior to CPIs. Following rechallenge with chemotherapy, response was recorded in 23 (82%) patients experiencing complete remission and 3 (11%) patients experiencing partial remission. The tumour evolution of the patients inferred by CALDER seemingly occurred prior to the first cycle of therapy and was characterized either by linear or branching evolution patterns.Twenty-five patients proceeded to allogeneic stem cell transplantation. At a median follow-up of 21 months, median PFS and OS were not reached. In conclusion, patients who fail CPIs can be effectively rescued by salvage chemotherapy and bridged to allo-SCT/ auto-SCT.</p>
Transcriptomic analysis of Platycodin D (PD)-improved idiopathic pulmonary fibrosis (IPF) mice
GEO Series GSE317792. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
An engineered mycobacterium smegmatis expressing anti-PD-L1/IL-15 immunocytokine induces and activates specific antitumor immunity
GEO Series GSE280146. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
PD-1-PD-L1 Axis Activation Suppresses CD8+ T Cells and Improves Nephritis.
GEO Series GSE228813. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Role of tRNA-derived fragments in the cross-talk between immune cells and beta cells during type 1 diabetes pathogenesis (PD in vivo)
GEO Series GSE242563. Mus musculus. 10 samples. Type: Non-coding RNA profiling by high throughput sequencing.
MicroRNA (miRNA) expression profiling of blood leukocytes of Parkinson's disease (PD) patients pre- and post-deep brain stimulation treatment and of healthy control volunteers
GEO Series GSE38385. synthetic construct; Homo sapiens. 13 samples. Type: Non-coding RNA profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.