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6,467 results for “process”
Modulation of Multidrug Resistance Protein 1-mediated transport processes by the antiretroviral drug ritonavir
<p>We here provide the structure files, trajectories and topology files for analyzing and reproducing simulations performed in the publication: "<strong>Modulation of Multidrug Resistance Protein 1-mediated transport processes by the antiretroviral drug ritonavir</strong>".</p> <p>Classical molecular dynamics simulation of rat Mrp1 have been performed in complex with native substrates like GSH and GSSG or drug molecules like ritonavir, to study binding modes of different combinations. </p> <p>Structure and trajectory files (all 1 µs long) as well as recorded movies of the time progression are provided for the following simulation systems:</p> <p>1. GSH bound to rat Mrp1</p> <p>2. GSSG bound to rat Mrp1</p> <p>3. Ritonavir bound to rat Mrp1</p> <p>4. GSH + Ritonavir bound to rat Mrp1</p> <p>5. GSSG + Ritonavir bound to rat Mrp1</p> <p>Additionally itp files (GROMACS format) containing parameter information about the ligands GSH, GSSG and Ritonavir are provided for the force field CHARMM36m. </p> <p>Raw data of the homology modeling of rat Mrp1 by I-Tasser as well as Docking results produced via AutoDock4 are uploaded as zip directories. </p> <p> </p>
Transnasal endoscopic approach for osteoid osteoma of the odontoid process in a child
<p>Transnasal endoscopic approach for osteoid osteoma of the odontoid process in a child</p>
Dataset supplementing "B. Ojha, M. Schober, S. Turad, J. Jochum and H. Kohler; Gasification of biomass: Very sensitive monitoring of TAR in syngas by determination of the oxygen demand– A proof of concept,Processes 2022"
<p>Dataset supplementing "B. Ojha, M. Schober, S. Turad, J. Jochum and H. Kohler;Gasification of biomass: Very sensitive monitoring of TAR in syngas by determination of the oxygen demand– A proof of concept,Processes 2022 "</p>
Data from: Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast
Cells respond to their environment by modulating protein levels through mRNA transcription and post-transcriptional control. Modest observed correlations between global steady-state mRNA and protein measurements have been interpreted as evidence that mRNA levels determine roughly 40% of the variation in protein levels, indicating dominant post-transcriptional effects. However, the techniques underlying these conclusions, such as correlation and regression, yield biased results when data are noisy, missing systematically, and collinear---properties of mRNA and protein measurements---which motivated us to revisit this subject. Noise-robust analyses of 24 studies of budding yeast reveal that mRNA levels explain more than 85% of the variation in steady-state protein levels. Protein levels are not proportional to mRNA levels, but rise much more rapidly. Regulation of translation suffices to explain this nonlinear effect, revealing post-transcriptional amplification of, rather than competition with, transcriptional signals. These results substantially revise widely credited models of protein-level regulation, and introduce multiple noise-aware approaches essential for proper analysis of many biological phenomena.
Harmony Point Chinstrap penguin GPS and Time-Depth-Recorder processed data
<p>Tracking data from Chinstrap Penguins (<em>Pygoscelis antarcticus</em>) tracked with axy-trek marine loggers in Harmony Point (Nelson Island, Maritime Antarctic Peninsula) in the breeding seasons of 2019/20 and 2021/22.</p> <p>The zip file is composed of two folders containing outputs from the R script named "GPS_TDR_processing.R", which process raw data from Axy-trek marine loggers producing 3 outputs that are within each of the folders. The outputs are: (1) 5-min resampled foraging trips (with trip ID identified), (2) dive statistics and (3) foraging trip summaries.</p> <p> </p> <p>Each file is named as the TagID, type of data (GPS or TDR), period (IB for late incubation / brooding - from late december to early january; CR for Chick-Rearing, from early to mid January) and season (2019/20 as 19 and 2021/22 as 21).</p> <p> </p> <p>GPS data is composed of the fields: Date (YYYY-mm-dd HH:MM:SS), distances, trip number and geographical coordinates in "+proj=longlat +datum=WGS84 +no_defs".</p> <p>TDR data is composed of outputs from dive statistics summarized using the "diveMove" R package. </p>
Analyzing Polyethylene Terephthalate Bottle Waste Technology Using Analytic Hierarchy Process for Developing Countries: A case Study from Indonesia
<p>PET bottle waste is easy to recycle because it is easy to separate, abundant, and competitively priced. Technologies for the treatment of PET bottle waste have been evaluated to date using life cycle assessment (LCA), but this does not take into account all the aspects that policy makers consider necessary to select an acceptable technology. Aspects such as society, economics, policies, and technical applicability need to be considered along with environment and resources consumption to complement the LCA results for PET bottle waste. These aspects were selected as criteria for the Analytical Hierarchy Process (AHP), and stakeholders were invited to make a comparison evaluation of the criteria and sub criteria. Academics were involved to compare the technology option. The results show that society is the highest priority because it is the main actor that ensures the application of the technology, and job creation is the most important indicator for the selection of the technology. After comparing open landfill, sanitary landfill, incineration with energy recovery, pelletizing, glycolysis, and hydrolysis for utilization of PET bottle waste, this study suggests pelletizing as the acceptable technology for Indonesia because pelletizing is supported by social aspects and creates more jobs. This is the first time that a single plastic fraction that is easy to collect and recycle has been studied with AHP. The results show that this type of plastic could also be reused in developing countries through mechanical recycling.</p>
Supplementary data to 'acquisition and processing methods of whole-brain layer-fMRI VASO and BOLD: The Kenshu dataset'
<p>Supplemental results of our analysis</p>
Data available for ''Vertical Gradient of Size-Resolved Aerosol Composition over the Arctic Reveals Cloud Processed Aerosol in-cloud and above Cloud"
<p>Folder containing the data of CCSEM and STXM measurements.</p>
Application of blender speed control technology in the processing of salak pondoh into coffee in Sibolong Hamlet
<p>Dukuh Sibolong consists of nine RTs with a total population of 672. Based <br> on the information our team got from Mr. Suharno as the head of the hamlet. <br> The hamlet has several groups of informal community organizations such as <br> youth organizations, PKK women. The majority of the population of Sonyo <br> Hamlet are Muslim and have a livelihood as laborers, but there are also those <br> who work as entrepreneurs because the geographical location of Sibolong <br> Hamlet is located in the highlands. Actually, the hamlet of Sibolong has <br> natural potential in the form of Salak Pondoh. One of these has just been <br> processed into salak syrup. The potential of salak is managed by Mr. Suharno. <br> Mr. Suharno has a market opportunity of up to 600 products per month. <br> However, this opportunity brings consequences and problems, namely the <br> wrong seed grinding machine is not owned. Information about some of the <br> problems faced by the zalacca processors must of course be addressed as soon <br> as possible as a solution for developing the zalacca processing business. The <br> team that proposes service as part of the community who happens to be <br> involved in the world of education, feels compelled to help provide solutions <br> to the problems faced by Mr. Suharno's salak processing business. Through <br> this proposed program of science and technology activities and based on the <br> needs analysis that has been carried out, the service team tries to offer <br> solutions to these problems with a touch of science and technology, namely <br> through the main activity of designing a salak seed grinder to make salak <br> coffee. The solosi is used to improve the processing of salak coffee.</p>
Diversification process between monogenoids (Dactylogyridae) and their marine catfish (Siluriformes: Ariidae) from the Atlantic coast of South America
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Investigating multi-physical process and deformation mechanism of reservoir landslide using integrated multi-source monitoring
<p>Data to support this study are available.</p>
The process of finding the categories of performance regression challenges
<p>This file is supplemental to a conference submission. </p>
Robust and fast post-processing of single-shot spin qubit detection events with a neural network
<p>Dataset to the paper 'Robust and fast post-processing of single-shot spin qubit detection events with a neural network'</p>
On the Understandability of Temporal Properties Formalized in Linear Temporal Logic, Property Specification Patterns and Event Processing Language
<p>Experimental material & data</p>
Supplementary material 1 from: Dhar MK, Kour G, Kaul S (2017) B chromosome in Plantago lagopus Linnaeus, 1753 shows preferential transmission and accumulation through unusual processes. Comparative Cytogenetics 11(2): 375-392. https://doi.org/10.3897/compcytogen.v11i2.11779
Tables S1 and S2 : Explanation note: Table S1: Sequences of primers used for SSR analysis.
Figure 5 from: Keshavan A, Madan CR, Datta E, McDonough IM (2017) Mindcontrol: Organize, quality control, annotate, edit, and collaborate on neuroimaging processing results. Research Ideas and Outcomes 3: e12276. https://doi.org/10.3897/rio.3.e12276
Figure 5 - Example of new scatterplot function. Structural Foreground to Background Energy Ratio is positively related with Structural Contrast to Noise Ratio. Single data points can also be highlighted to detect outlers.
Figure 4 from: Keshavan A, Madan CR, Datta E, McDonough IM (2017) Mindcontrol: Organize, quality control, annotate, edit, and collaborate on neuroimaging processing results. Research Ideas and Outcomes 3: e12276. https://doi.org/10.3897/rio.3.e12276
Figure 4 - Example of scatterplot function to display the relationship of metrics in longitudinal data
Figure 2 from: Keshavan A, Madan CR, Datta E, McDonough IM (2017) Mindcontrol: Organize, quality control, annotate, edit, and collaborate on neuroimaging processing results. Research Ideas and Outcomes 3: e12276. https://doi.org/10.3897/rio.3.e12276
Figure 2 - The longitudinal view of a single subject and their quality metrics over time. Clicking on a point on the plots on the left-hand side loads the correponding image on the right.
THE PROCESS OF MANAGEMENT DECISION MAKING IN ORGANIZATIONS
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MIGRATION PROCESSES TO THE LANGUAGE IN THE INFLUENCE TO HIMSELF CHARACTERISTIC
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ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.