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3,508
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ShareScore release 0.9.0
Dataset results
3,508 results for “reprogramming”
The AP-1 transcription factor FOSL1 causes melanocyte reprogramming and transformation
GEO Series GSE85086. Homo sapiens. 2 samples. Type: Expression profiling by array.
Comprehensive screens and a universal zinc finger model enable transcription factor reprogramming 2 factor reprogrammingComprehensive screens and a universal zinc finger model enable transcription fa
GEO Series GSE215330. Homo sapiens. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome reprogramming in Saccharomyces cerevisiae upon nonylphenol exposure
GEO Series GSE96651. Saccharomyces cerevisiae; Schizosaccharomyces pombe. 18 samples. Type: Expression profiling by array.
Global gene expression profile of reprogrammed osteosarcoma cell lines, iG-292 and iSaos-2.
GEO Series GSE107855. Homo sapiens. 10 samples. Type: Expression profiling by array.
Dynamic 3D Genome and Epigenetic Landscapes of Macrophage Cells Reprogramming Gene Expression during Differentiation and Infection [sciDLO Hi-C]
GEO Series GSE159501. Homo sapiens. 3 samples. Type: Other.
MAPK14 Governs Mammalian Müller glia Fate Determination between Gliosis and Reprogramming
GEO Series GSE316279. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer "
<p>This record contains raw data related to article “Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer"</p> <p>Although chemotherapeutic agents have been used for decades, the mechanisms of action, mechanisms of resistance, and the best treatment schedule remain elusive. Mitomycin C (MMC) is the gold standard treatment for non-muscle-invasive bladder cancer (NMIBC). However, it is effective only in a subset of patients, suggesting that, aside from cytotoxicity, other mechanisms could be involved in mediating the success of the treatment. Here, we showed that MMC promotes immunogenic cell death (ICD) and in vivo tumor protection. MMC-induced ICD relied on metabolic reprogramming of tumor cells toward increased oxidative phosphorylation. This favored increased mitochondrial permeability leading to the cytoplasmic release of mitochondrial DNA, which activated the inflammasome for efficient IL-1β (interleukin-1β) secretion that promoted dendritic cell maturation. Resistance to ICD was associated with mitochondrial dysfunction related to low abundance of complex I of the respiratory chain. Analysis of complex I in patient tumors indicated that low abundance of this mitochondrial complex was associated with recurrence incidence after chemotherapy in patients with NMIBC. The identification of mitochondria-mediated ICD as a mechanism of action of MMC offers opportunities to optimize bladder cancer management and provides potential markers of treatment efficacy that could be used for patient stratification.</p>
Proteomic profiling during human cellular reprogramming identifies distinct protein clusters and novel markers of induced pluripotent stem cells
Open the record for dataset details and reuse information.
Tri-modal single cell profiling reveals a distinct pediatric CD8αα T cell subset and broad age-related molecular reprogramming across the T cell compartment
<p>Please use updated Zenodo: https://zenodo.org/records/10372039</p>
Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy. [RNA-Seq]
GEO Series GSE249544. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
LIX1L aggravates NASH-HCC progression by reprogramming of hepatic Metabolism and microenvironment via CD36
GEO Series GSE264479. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
SINE-MIR enhancer rewiring by Esrrb architecturally reprogram the pluripotency spectrum [ATAC-Seq]
GEO Series GSE246863. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
EIF5A couples translational control with transcriptional reprogramming through chromocenter reorganization during spermiogenesis [ATAC-Seq]
GEO Series GSE302914. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mycobacterial cord factor reprograms the macrophage response to IFN-gamma towards enhanced inflammation yet impaired antigen presentation and expression of Gbp1
GEO Series GSE137150. Mus musculus. 42 samples. Type: Expression profiling by array.
Loss of Nuclear Receptor Nr4a3 Alleviates Cellular Senescence to Promote Adult Direct Cardiac Reprogramming (CUT&Tag)
GEO Series GSE267448. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
TFAP2C affects epigenetic reprogramming of porcine embryo development by regulating global epigenetic modification
GEO Series GSE230288. Sus scrofa. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional and Phenotypic Reprogramming of Tumors by Host Stroma Deficient in TNFα Signaling
GEO Series GSE23002. Mus musculus. 8 samples. Type: Expression profiling by array.
The 40S-LARP1 complex reprograms the cellular translatome upon mTOR inhibition to preserve the protein synthetic capacity
GEO Series GSE186779. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy. [array]
GEO Series GSE249636. Homo sapiens. 36 samples. Type: Methylation profiling by array.
Metabolic reprogramming and ferroptosis occurring in granulosa cells from patients with diminished ovarian reserve
GEO Series GSE286918. Homo sapiens. 116 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.