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7,370 results for “supplementation”
Figure 1 from: Hasegawa N, Hookabe N, Fujiwara Y, Jimi N, Kajihara H (2024) Supplemental re-description of a deep-sea ascidian, Fimbrora calsubia (Ascidiacea, Enterogona), with an inference of its phylogenetic position. Zoosystematics and Evolution 100(1): 129-140. https://doi.org/10.3897/zse.100.113132
Figure 1 Maps showing the sampling site (red circle), south of Houei Seamount (of which the top is indicated with a red triangle). The images were generated by using GMT 6 (Wessel et al. 2019), based on grid data provided by the General Bathymetric Chart of the Oceans.
Supplemental video - Actin microbes
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Supplemental Table and Figures for TSH Trajectories in the ELSA-Brasil Cohort
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Supplemental material for the paper, "Entropy, Search Trajectories, and Explainability for Frequency Fitness Assignment"
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Peregrine supplement
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raw data - The Efficacy of Calcium and Vitamin D3 Supplementation in Improving Pregnancy and Neonatal Outcomes
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Clouseau: Supplemental material for PLDI 2025
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Supplemental Table S1 Summary of clinical, histological and immunohistochemical results
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The Influence of Study Quality, Age, and Geographic Factors on Polycystic Ovary Syndrome Prevalence-A Systematic Review and Meta-Analysis (Supplemental data)
<p><strong><span>Supplemnatray data for manuscript tentatively entitled "The Influence of Study Quality, Age, and Geographic Factors on </span></strong><strong><span>Polycystic Ovary Syndrome Prevalence</span></strong><strong><span>-A Systematic Review and Meta-Analysis", including: </span></strong></p> <p><strong><span>Supplementary Table 1.</span></strong><span> Search strategy and its results including studies published until February 29<sup>th</sup> of 2024.</span></p> <p><strong><span>Supplementary Table 2.</span></strong><span> The quality assessment results of studies conducted on adults based on the Polycystic ovary syndrome (PCOS) Epidemiology and Phenotype (PEP) tool. </span></p> <p><strong><span>Supplementary Table 3.</span></strong><span> The quality assessment results of studies conducted on adolescents based on <a name="_Hlk176077530"></a>the Polycystic ovary syndrome (PCOS) Epidemiology and Phenotype (PEP) tool. </span></p> <p><strong><span>Supplementary Table 4.</span></strong><span> The quality assessment results of studies conducted on mixed populations (both adults and adolescents) based on PCOS Epidemiology and Phenotype (PEP) tool. </span></p> <p><strong><span>Supplementary Figure 1 (A-D). </span></strong><span>Forest plots of global PCOS prevalence stratified by diagnostic criteria (regardless of study quality, age group, and geographic region): A) NIH, B) Rotterdam, C) AE-PCOS, D) Self-report: A) NIH, B) Rotterdam, C) AE-PCOS, D) Self-report.</span></p> <p><strong><span>Supplementary Figure 2 (A-C</span></strong><span>). Forest plots of global PCOS prevalence stratified by WHO region and diagnostic criteria (regardless of study quality and age group): A) NIH, B) Rotterdam, C) AE-PCOS.</span></p> <p><strong><span>Supplementary Figure 3 (A-C).</span></strong><span> </span><a name="_Hlk174390393"></a><span>Forest plots of PCOS prevalence stratified by diagnostic criteria and age group (adults vs. adolescent) (regardless of study quality): A) NIH, B) Rotterdam, C) AE-PCOS.</span></p> <p><strong><span>Supplementary Figure 4 (A-C).</span></strong><span> Sensitivity Analysis based on high-quality studies: Impact of individual study exclusion on pooled prevalence</span> <span>(using high-quality studies only)- A) NIH, B) Rotterdam, C) AE-PCOS.</span></p>
Supplemental materials for manuscript: Stelmachowska-Banas et al. 2024 "Endocrine alterations in patients with pachydermoperiostosis". Submission to Journal of Clinical Endocrinology and Metabolism.
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Supplemental Files
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Figure 1 from: Koleva P, Tsanova-Savova S, Paneva S, Velikov S, Savova Z (2021) Polyphenols content of selected medical plants and food supplements present at Bulgarian market. Pharmacia 68(4): 819-826. https://doi.org/10.3897/pharmacia.68.e71460
Figure 1 Chromatogram of Standard mix of (+)-catechin, (-)-epicatechin and rutin at 275 nm (a) and 355 nm (b).
Data Supplements - N-of-1 trials in neurological disorders: Personalizing treatment
<p><strong>Supplemental data including</strong>: Study details of each included N-of-1 trial that reported individual responses (on a pre-defined primary outcome measure) and post-trial treatment decisions (eTable 1); PubMed and Medline primary search strategy for N-of-1 trials in neurological disorders (eAppendix 1); More specified inclusion and exclusion criteria (eAppendix 2); eReferences (eReferences).</p>
Supplement video_Aging Skin Model
<p>Supplementary video for Aging Skin Model </p>
F2R polymorphisms and clopidogrel efficacy and safety in patients with minor stroke or TIA: supplemental figures and tables
<p><b>Objective</b>: To investigate the association between protease-activated receptors-1 (PAR-1) gene<i> F2R</i> polymorphisms and efficacy of clopidogrel for minor stroke or transient ischemic attack (TIA).</p> <p><b>Methods</b>: Three single-nucleotide polymorphisms (<i>CYP2C19*2</i> [681G>A, rs4244285], <i>CYP2C19</i>*<i>3</i> [636G>A, rs4986893] and <i>F2R</i> [IVSn-14 A/T, rs168753] were genotyped among<span> 2,924 patients randomized to clopidogrel plus aspirin (n=1461) or aspirin alone (n=1463). </span>The primary efficacy outcome was new stroke (ischemic or hemorrhagic) and the safety outcome was any bleeding.</p> <p><b>Results: </b>Overall, 859(29.4%) were AA homozygotes, 1479(50.6%) were AT heterozygotes and 586(20.0%) were TT homozygotes for <i>F2R</i> IVSn -14 polymorphisms; 1716 (58.7%) were carriers of at least one<i> CYP2C19</i> loss-of-function allele (*2 or *3). Compared with aspirin alone, patients with clopidogrel-aspirin treatment had a low risk of new stroke in patients with AT genotype (7.6% <i>vs.</i> 11.3%; hazard ratio [HR], 0.63; 95% confidence interval [CI], 0.44-0.89) and TT genotype (5.8% <i>vs.</i> 11.6%; HR, 0.46; 95% CI, 0.25-0.82) but not in carriers of the AA genotype (10.8% <i>vs.</i> 11.6%; HR, 0.95; 95% CI, 0.63-1.44) (p=0.03 for interaction). The association between <i>F2R</i> IVSn -14 A/T polymorphism and clopidogrel response was present regardless of the carrier status of the <i>CYP2C19</i> loss-of-function alleles. The<i> F2R</i> IVSn -14 genotypes were not associated with the risk of any bleeding for clopidogrel-aspirin treatment (P=0.66 for interaction).</p> <p><span><b>Conclusions:</b><b> </b></span>Among patients with minor ischemic stroke or TIA who were receiving clopidogrel and aspirin, those carrying <i>F2R</i> IVSn -14 T allele had a lower rate of recurrent stroke than those who were not.</p> <p><span><b>Clinicaltrials.gov Identifier:</b></span> NCT00979589.</p>
Supplemental Data - Intact Drosophila Whole Brain Cellular Quantitation reveals Sexual Dimorphism
<p>Supplemental Figures, Datasets and Movies supporting the manuscript -</p> <p><strong>Intact Drosophila Whole Brain Cellular Quantitation reveals Sexual Dimorphism</strong>. Wei Jiao, Gard Spreemann, Evelyne Ruchti, Soumya Banerjee, Ying Shi, R. Steven Stowers, Kathryn Hess and Brian D. McCabe<br> <br> Brain Mind Institute, EPFL - Swiss Federal Institute of Technology Lausanne, Switzerland - <a href="https://mccabelab.org">https://mccabelab.org</a></p>
Supplemental materials for Glucocorticoid production in lymphoid organs: Acute effects of lipopolysaccharide in neonatal and adult mice
<p>Supplemental materials for "Glucocorticoid production in lymphoid organs: Acute effects of lipopolysaccharide in neonatal and adult mice" submitted to <em>Endocrinology</em>.</p> <p><strong>Abstract:</strong><br> Glucocorticoids (GCs) are critical modulators of the immune system. The hypothalamic-pituitary-adrenal (HPA) axis regulates circulating GC levels and is stimulated by endotoxins. Lymphoid organs also produce GCs; however, it is not known how lymphoid GC levels are regulated in response to endotoxins. We assessed whether an acute challenge of lipopolysaccharide (LPS) increases lymphoid levels of GCs, steroidogenic enzymes expression, and components of the HPA axis (e.g., CRH) expression. We administered LPS (50µg/kg i.p.) or vehicle control to male and female C57BL/6J neonatal (post-natal day (PND) 5) and adult (PND90) mice and collected blood, bone marrow, thymus, and spleen 4 hr later. We measured progesterone, 11-deoxycorticosterone (DOC), corticosterone, and 11-dehydrocorticosterone (DHC) via liquid chromatography tandem mass spectrometry (LC-MS/MS). We measured gene expression of key steroidogenic enzymes (<em>Cyp11b1</em>, <em>Hsd11b1</em>, and <em>Hsd11b2</em>) and HPA axis components (<em>Crh</em>, <em>Crhr1</em>, <em>Pomc</em>, and <em>Mc2r</em>) via qPCR. At PND5, LPS induced greater increases in steroid levels in lymphoid organs than in blood. In contrast, at PND90, LPS induced greater increases in steroid levels in blood than in lymphoid organs. Steroidogenic enzyme transcripts were present in all lymphoid organs, and LPS altered steroidogenic enzyme expression predominately in the spleen. Lastly, we detected transcripts of key HPA axis components in all lymphoid organs, and there was an effect of LPS in the spleen. Taken together, these data suggest that LPS regulates GC production by lymphoid organs, similar to its effects on the adrenal glands, and the effects of LPS might be mediated by local expression of CRH and ACTH.</p>
Supplemental data. Experimentally manipulated food availability affects offspring quality but not quantity in zebra finch meso-populations
<p>Data used for the publication: " Experimentally manipulated food availability affects offspring quality but not quantity in zebra finch meso-populations "</p>
Supplemental Material to "Artificial Music Producer: Filtering Music Compositions by Artificial Taste"
<p>The paper can be found here: <a href="https://doi.org/10.5281/zenodo.7088395">doi.org/10.5281/zenodo.7088395</a></p>
Supplemental materials for: Implementation and evaluation of an objective structured clinical examination (OSCE) tool for neurology post-graduate trainees in Lusaka, Zambia
<p>Introduction: Despite the high burden of neurologic disease in Zambia, a low-middle income sub-Saharan African country of 18 million people, there are currently no Zambian neurologists. We established the first neurology residency program in Zambia at the University of Zambia School of Medicine and the University Teaching Hospital in Lusaka. We evaluated the feasibility and effectiveness of a modified Objective Structured Clinical Examination (OSCE) to assess clinical skills. </p> <p>Program Description: The neurology training program began in October 2018, and its 3 participants completed the OSCE exercise in February 2019. The exercise involved using a smartphone to videotape trainees performing a physical examination and oral presentation in the neurology clinic. Trainees and neurology faculty reviewed the videos independently and assessed performance using a standardized rubric. The faculty and trainee then met in person and discussed the activity and scoring rubric. </p> <p>Assessment & Outcomes: Three trainees completed pre- and post-OSCE surveys where they rated their confidence in elements of the history and neurological examination and provided feedback about the OSCE exercise. One faculty member reviewed each video and provided feedback to each trainee. Trainees' average self-confidence scores improved from the pre- to post-OSCE survey in every category (pre-OSCE: mean score 6.84, range 4.8-7.8, SD 0.92; post-OSCE: mean score 7.9, range 5.67-9.33, SD 0.86). Qualitative responses showed trainees found the OSCE helpful, routinely applied feedback, and would appreciate repeating OSCEs every few months. </p> <p>Lessons Learned: This study demonstrated that OSCEs can be modified and successfully implemented in a resource-limited neurology post-graduate training program and result in improved self-confidence among trainees. Important modifications to the OSCE involved using smartphones to videotape the OSCE's and a real patient encounter rather than a standardized patient. Because there are many neurology patients and few providers in Zambia, embedding the experience within a busy clinic day was practical, directly applicable, and at a lower opportunity cost. </p> <p>Future Directions: Future work should expand use of OSCEs both within the Zambian neurology residency program and non-neurology training programs. Including additional video reviewers could add to the validity of clinical skills assessment. Videos created could also be used for remote mentorship and teaching purposes.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.