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1,065 results for “Gut microbiota”
Influence of Mediterranean Foods on Gut Microbiota Functionality in Obese Children Compared to Lean Children (Supplemental information)
<p>Complete dataset including the antioxidant capacity for all foods tested with 3 antioxidant method.</p>
Effects of pollen supply on Apis mellifera worker longevity and body weight in the presence and absence of an intact gut microbiota
<p>Gut microbiota are known to foster pollen digestion in honey bee workers, <em>Apis mellifera</em>, thereby enhancing longevity and body weight gain. However, it is currently not known how longevity and body weight gain are effected when gut microbiota are reduced in bees with or without access to pollen. Here, using a hoarding cage set-up with freshly emerged summer workers, we manipulated the gut microbiota of half the bees with the antibiotic tetracycline (ABX), and left the other half untreated on a sucrose solution diet. Afterwards, all bees were assigned to either sucrose diets or sucrose plus <em>ad libitum</em> access to pollen (N=4 treatments, N=26 bees/treatment, N=10 replicates/treatment, N=1040 total workers). The data confirm that pollen has a positive effect on longevity and body weight in workers with an unmanipulated gut microbiota. Surprisingly, the antibiotics alone also improved the longevity and body weight of the workers fed a strictly sucrose diet, potentially explained by the reduction of harmful bacteria. However, this positive effect was always reversed in the presence of pollen, underscoring the innate value of natural microbiota on pollen digestion. In conclusion, a combination of adequate pollen supply and an intact gut microbiota appears crucial to honey bee worker health, calling for respective efforts to ensure both in managed colonies.</p>
A soil fungus confers plant resistance against a phytophagous insect by disrupting the symbiotic role of its gut microbiota
<p>Dataset related to the manuscript titled "A hidden interkingdom competition underlies plant-insect interactions".</p> <p>Please, read the README.txt file for more info about zipped data content. </p>
Effect of gut microbiota on α-amanitin tolerance in Drosophila tripunctata
<p><span>The bacterial gut microbiota of many animals is known to be important for many physiological functions including detoxification. The selective pressures imposed on insects by exposure to toxins may also be selective pressures on their symbiotic bacteria, who thus may contribute to the mechanism of toxin tolerance for the insect. Amatoxins are a class of cyclopeptide mushroom toxins that primarily act by binding to RNA polymerase II and inhibiting transcription. Several species of mycophagous <i>Drosophila </i>are tolerant to amatoxins found in mushrooms of the genus <i>Amanita</i>, despite these toxins being lethal to most other known eukaryotes. These species can tolerate amatoxins in natural concentrations to utilize toxic mushrooms as larval hosts, but the mechanism by which these species are tolerant remains unknown. Previous data has shown that a local population of <i>D. tripunctata</i> exhibits significant genetic variation in toxin tolerance. This study assesses the potential role of the microbiome in α-amanitin tolerance in six wild-derived strains of <i>Drosophila tripunctata</i>. Normal and antibiotic-treated samples of six strains were reared on diets with and without α-amanitin, and then scored for survival from the larval stage to adulthood and for development time to pupation. Our results show that a substantial reduction in bacterial load does not influence toxin tolerance in this system, while confirming genotype and toxin-specific effects on survival are independent of the microbiome composition. Thus, we conclude that this adaptation to exploit toxic mushrooms as a host is likely intrinsic to the fly's genome and not a property of their microbiome.</span></p>
Association of lymph node metastasis of hepatocellular carcinoma with the gut microbiota, bile acid metabolism, and MIP-1α
<p>Supplementary figures for the manuscript.</p>
Development of an in vitro model of the gut microbiota enriched in mucus-adhering bacteria
<p>16S rRNA gene sequencing data in FASTQ format</p>
Genistein Stimulates Insulin Sensitivity Through Gut Microbiota
ClinicalTrials.gov study NCT04105023. IPD Sharing: NO. Countries: 0. Publications: 4.
Gut Microbiota and Diarrhea in Breast Cancer Patients Receiving Pyrotinib
ClinicalTrials.gov study NCT07264985. IPD Sharing: NO. Countries: 1. Publications: 0.
Deciphering the Role of the Gut Microbiota in Multiple Sclerosis
ClinicalTrials.gov study NCT02580435. IPD Sharing: Not stated. Countries: 0. Publications: 8.
Involvement of the Gut Microbiota in Calcified Aortic Stenosis
ClinicalTrials.gov study NCT06021535. IPD Sharing: NO. Countries: 0. Publications: 6.
Dietary Intervention Modifies Gut Microbiota in Type 2 Diabetes.
ClinicalTrials.gov study NCT03421301. IPD Sharing: NO. Countries: 0. Publications: 25.
Effects of Grape Powder on Psychological Distress and Gut Microbiota in College Students
ClinicalTrials.gov study NCT07214428. IPD Sharing: NO. Countries: 1. Publications: 0.
Gut Microbiota Changes in Obese Individuals Undergoing Dedicated Lifestyle Modification Programs
ClinicalTrials.gov study NCT02855242. IPD Sharing: YES. Countries: 1. Publications: 0.
Effect of Probiotics on Gut Microbiota During the Helicobacter Pylori Eradication
ClinicalTrials.gov study NCT05662514. IPD Sharing: NO. Countries: 0. Publications: 4.
Golimumab Effect in the Modulation of Gut Microbiota in Ulcerative Colitis
ClinicalTrials.gov study NCT03018925. IPD Sharing: NO. Countries: 1. Publications: 0.
Gut Microbiota Dysbiosis in Opioid Use Disorders: Implications for Clinical Symptoms and Relapse Rate.
ClinicalTrials.gov study NCT06231849. IPD Sharing: UNDECIDED. Countries: 0. Publications: 3.
The Role of Gut Leakage Markers and Microbiota Signature in Coronary Artery Disease.
ClinicalTrials.gov study NCT04605627. IPD Sharing: YES. Countries: 1. Publications: 0.
Effects of the Bifidobacterium Longum BL21 on BMI, Metabolic Indicators, and Gut Microbiota in Overweight/Obese Adults
ClinicalTrials.gov study NCT06140641. IPD Sharing: NO. Countries: 0. Publications: 1.
Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease
ClinicalTrials.gov study NCT02765256. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Observational Study of Gut Microbiota in Abemaciclib-Treated Patients With and Without Diarrhea
ClinicalTrials.gov study NCT07264998. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.