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Dataset results
752 results for “Osteoporosis”
Cardiotrophin Like Cytokine Factor 1 (CLCF1) alleviates bone loss and osteoclastogenesis in osteoporosis mouse models through activating interferon signaling and repressing the nuclear factor-κB signa
GEO Series GSE177024. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Unique gender-dependent serum microRNA profile in PLS3 osteoporosis in PLS3 gene related osteoporosis
GEO Series GSE142872. Homo sapiens. 29 samples. Type: Expression profiling by RT-PCR.
An atlas of genetic influences on osteoporosis in humans and mice
GEO Series GSE120755. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Next Generation Sequencing Facilitates Quantitative Analysis of Zebrafish Osteoporosis Model Transcriptomes
GEO Series GSE194301. Danio rerio. 25 samples. Type: Expression profiling by high throughput sequencing.
Altered MicroRNA Profile in Osteoporosis Caused by Impaired WNT signaling
GEO Series GSE103473. Homo sapiens. 24 samples. Type: Other.
Novel Role for Alpha-2-Macroglobulin (A2M) as a Disease Modifying Protein in Senile Osteoporosis
GEO Series GSE243475. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
The pivotal role of the Hes1–Piezo1 pathway in the pathophysiology of glucocorticoid-induced osteoporosis
GEO Series GSE276391. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Single cell analysis reveals the myeloid-biased hematopoiesis and leukemic evolution programs initiated by Brd4 in HSPCs of mice with disuse osteoporosis
GEO Series GSE281970. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic analysis of the bone reveals the mechanism of Desertliving Cistanche herb in ovariectomized rats of postmenopausal osteoporosis
GEO Series GSE208290. Rattus norvegicus. 9 samples. Type: Expression profiling by high throughput sequencing.
FDPS-regulated transcriptome profile revealed its potential functions in osteoporosis as an RNA binding protein
GEO Series GSE151605. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Identification of miRNAs Related to Osteoporosis by High-throughput Sequencing
GEO Series GSE273345. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Functional change of mouse skeletal stem cells correlated with the progression of osteoporosis
GEO Series GSE214645. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome of bone marrow cells from mice with osteoporosis induced bu hindlimb unloading
GEO Series GSE281210. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Zingerone treats postmenopausal osteoporosis via increased ferroptosis sensitivity by p53-mediated regulation of Sat1 and Gpx4 expression
GEO Series GSE304652. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
NVP-BHG712 alleviates ovariectomy-induced osteoporosis by modulating osteoclastogenesis
GEO Series GSE261350. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Data from: Predictors of nephrolithiasis, osteoporosis and mortality in primary hyperparathyroidism
Context: Primary Hyperparathyroidism (PHPT) has a prevalence of 0.86% and is associated with increased risk of nephrolithiasis and osteoporosis. PHPT may also be associated with an increased risk of cardiovascular disease and mortality. Objective: To identify risk factors for nephrolithiasis, osteoporosis and mortality in PHPT. Design: Retrospective cohort study. Setting: University teaching hospital. Patients: PHPT presenting between 2006 – 2014 (n = 611). Main outcome measures: Assessment of nephrolithiasis, osteoporosis and mortality. Results: 13.9% of PHPT patients had nephrolithiasis. Most had already documented stone disease and only 4.7% of asymptomatic patients screened for renal stones had calculi identified, not very dissimilar to the rate in the non-PHPT population. Younger age (P < 0.001) and male gender (P = 0.003) were the only independent predictors of nephrolithiasis. 48.4% of patients with DXA data had osteoporosis (223/461). Older age (P < 0.001), lower BMI (P = 0.002) and lower creatinine (P = 0.006) were independently associated with a diagnosis of osteoporosis. Higher PTH was independently associated with lower Z-score at the hip (P = 0.009), but otherwise calcium and PTH were not associated with lower Z-score. Mortality in PHPT was associated with older age (P < 0.008), social deprivation (P = 0.028) and adjusted calcium (P = 0.009) but not independently with PTH at diagnosis. Conclusions: Screening for nephrolithiasis has a low yield, particularly in lower risk patients. Osteoporosis is only minimally associated with biochemical indices of PHPT. Mortality is associated with higher calcium (and possibly vitamin D deficiency) but not PTH.
Figure 1 from: Ivanova S, Petkova V (2022) Specificity of clinical trials of some osteoporosis medicines. Pharmacia 69(1): 99-106. https://doi.org/10.3897/pharmacia.69.e79258
Figure 1 Chemical structures for Alendronbate, Ibandronate, Risedronate and Zoledronate.
Patient Education With or Without Physical Training or Mindfulness and Medical Yoga in Established Spinal Osteoporosis
ClinicalTrials.gov study NCT05227976. IPD Sharing: NO. Countries: 1. Publications: 0.
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Osteoporosis
ClinicalTrials.gov study NCT05152381. IPD Sharing: NO. Countries: 1. Publications: 0.
Psychological Impact of Quarantine in Osteoporosis Patient During COVID-19 Outbreak
ClinicalTrials.gov study NCT04351633. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.