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361
datasets available to search
ShareScore release 0.9.0
Dataset results
361 results for “derived response”
The response to PAM3CSK4 (PAM3) of bone marrow derived macrophages treated with 25-hydroxycholesterol (RNA-Seq).
GEO Series GSE201129. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Isogenic iPSC-derived proximal and distal lung-on-chip models reveal tissue and virus-specific immune responses in human lungs [Airway Top]
GEO Series GSE247676. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Whole blood derived cadmium responsive miRNome
GEO Series GSE73744. Mus musculus. 4 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Gene expression changes in cord blood-derived ECFCs in response to in vitro senescence stimuli
GEO Series GSE160166. Homo sapiens. 15 samples. Type: Expression profiling by array.
Nanostring gene expression data, comparison of response to subcutaneously implanted porcine-derived decellularized myocardial matrix hydrogels in mast cell deficient mice compared to deficient mice wi
GEO Series GSE218383. Mus musculus. 24 samples. Type: Expression profiling by array.
Adipose-derived Stem cll and Stronal Vascular Fraction response to inflammation sc RNA seq
GEO Series GSE270461. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
CCG-1423-derived compounds reduce global RNA synthesis and inhibit transcriptional responses
GEO Series GSE244232. Mus musculus; Drosophila melanogaster. 30 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Global mRNA translational landscapes in mouse bone-marrow-derived-macrophage-mediated response to LPS (lipopolysaccharide)
GEO Series GSE99787. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing; Other.
Isogenic iPSC-derived proximal and distal lung-on-chip models reveal tissue and virus-specific immune responses in human lungs
GEO Series GSE247677. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.
CCG-1423-derived compounds reduce global RNA synthesis and inhibit transcriptional responses (PRO-seq)
GEO Series GSE244231. Drosophila melanogaster. 8 samples. Type: Other.
AtGenExpress: Response to bacterial-(LPS, HrpZ, Flg22) and oomycete-(NPP1) derived elicitors
GEO Series GSE5615. Arabidopsis thaliana. 42 samples. Type: Expression profiling by array.
Effects of JNK on TGF-beta responses of mouse B lymphoma derived A20 cells
GEO Series GSE7503. Mus musculus. 6 samples. Type: Expression profiling by array.
Enhanced Innate Response In RB1 deficient Microglia Derived From Retinoblastoma Patient
GEO Series GSE212248. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy.
GEO Series GSE249637. Homo sapiens. 84 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by array.
Monocyte-derived dendritic cells response to mycobacterial glycolipid, phosphatidyl-inositol mannosides (PIM)
GEO Series GSE84740. Homo sapiens. 3 samples. Type: Expression profiling by array.
Dataset related to article "Identification of a class of non-conventional ER-stress response-derived immunogenic peptides (ERStreP)"
<p>This record contains raw data and scripts (R software) applied to get Figure 5 and Figure S8 related to article “Identification of a class of non-conventional ER-stress response-derived immunogenic peptides (ERStreP)”</p> <p>Immune checkpoint blockade (ICB) has changed the prognosis of previously untreatable tumors. However, a fraction of patients is refractory to ICB therapy. Ongoing efforts to overcome resistance have focused on vaccination strategies using neoepitopes, although these cannot be applied on a large scale due to the "private" nature of cancer mutations. Here we show that infection of tumor cells with <em>Salmonella</em> induces the opening of membrane hemichannels and the release of proteasome-generated peptides in the extracellular milieu via the exacerbation of endoplasmic reticulum (ER)-stress and the unfolded protein response. Peptides released by cancer cells induced a strong antitumor response <em>in vivo</em>, both in mice bearing B16F10 melanomas and in dogs suffering of osteosarcoma and high-grade sarcoma. Mass spectrometry analysis on the supernatant of human melanoma cells revealed 12 released peptides capable of priming healthy donor CD8<sup>+</sup> T cells that recognize and kill human melanoma cells <em>in vitro</em> and when xenotransplanted <em>in vivo</em>, but not healthy melanocytes. Hence, we identified a novel class of tumor antigens that are generated in ER-stressed cells, such as tumor cells, and that do not induce central or peripheral tolerance, nor are presented by healthy cells.</p> <p> </p>
Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy. [RNA-Seq]
GEO Series GSE249544. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy. [array]
GEO Series GSE249636. Homo sapiens. 36 samples. Type: Methylation profiling by array.
CCG-1423-derived compounds reduce global RNA synthesis and inhibit transcriptional responses (ChIP-seq)
GEO Series GSE243873. Mus musculus; Drosophila melanogaster. 22 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Activation of IFN/STAT1 signaling is a hallmark of response to chemotherapy in patient-derived xenografts of triple-negative breast cancer
GEO Series GSE58990. Homo sapiens. 28 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.