Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
986
datasets available to search
ShareScore release 0.9.0
Dataset results
986 results for “exchange”
Soil pH, exchangeable Al, and soil C in the surface soil (0–20 cm) of the Dinghushan (DHS) forest site
<p>To analyze soil acidification rate in Dinghushan, we compiled the data on soil pH, exchangeable Al, and soil C from 1982 to 2013.</p>
Mapping fast DNA polymerase exchange during replication
<h2>Abstract</h2> <p>Despite extensive studies on DNA replication, the exchange mechanisms of DNA polymerase during replication remain unclear. Existing models propose that this exchange is facilitated by protein partners like helicase. Here we present data, employing a combination of mechanical DNA manipulation and single fluorescent protein observation, that reveal DNA polymerase undergoing rapid and autonomous exchange during replication not coordinated by other proteins. The DNA polymerase shows fast unbinding and rebinding dynamics, displaying a preference for either exonuclease or polymerase activity, or pausing events, during each brief binding event. We also observed a 'memory effect' in DNA polymerase rebinding, i.e., the enzyme tends to preserve its prior activity upon reassociation. This effect, potentially linked to the ssDNA/dsDNA junction's conformation, might play a role in regulating binding preference enabling high processivity amidst rapid protein exchange. Taken together, our findings support an autonomous replication model that includes rapid protein exchange, burst of activity, and a 'memory effect' while moving processively forward. </p> <h2>Data Set Description</h2> <p>The study presents findings on the autonomous exchange mechanisms of DNA polymerase at the replication fork. Employing a combination of mechanical DNA manipulation and single fluorescent protein observation, the research reveals rapid and autonomous exchange of DNA polymerase, independent of protein partners like helicase. It highlights the enzyme's preference for exonuclease or polymerase activity and a 'memory effect' during binding events. In this data repo, we provided all the raw data used to reproduce the findings.</p> <h2>Methodology</h2> <p>The single-molecule experiments were performed at room temperature in a 5-channel microfluidic flow cell using the LUMICKS C-Trap instrument that combines dual optical trapping, confocal microscopy, and microfluidics for single-molecule assays. Data analysis was conducted using Python, Origin, and MATLAB. Detailed methodology and instrument specifications are provided in the associated publication.</p> <h2>File Formats</h2> <ul> <li> <p>All data is obtained from C-trap in .tdms format.</p> </li> </ul> <h2>Usage Notes</h2> <p>The custom-written python scripts used in this study is available at <a href="https://github.com/longfuxu/DNAPolymeraseProject">https://github.com/longfuxu/DNAPolymeraseProject</a>, under the MPL-2.0 license. The repository includes example dataset, example Jupiter notebook, along with a detailed README file for instructions on installation and usage.</p> <h2>Acknowledgments</h2> <p>We thank Seyda Aca and Sandrine D'Haene for assistance with protein purification and DNA construction, Noémie Danné for help with implementing the step-fitting algorithm. We thank Erwin Peterman for critical reading and constructive feedbacks of this manuscript. This work was financially supported by a PhD fellowship from China Scholarship Council (To L.X., funding No. 201704910912), the European Union H2020 Marie-Sklowdowska Curie International Training Network AntiHelix (To G.J.L.W., funding No. 859853), and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program MONOCHROME (to G.J.L.W., funding No.883240).</p> <h2>Competing Interest</h2> <p>The combined optical tweezers and fluorescence technologies used in this article are patented and licensed to LUMICKS B.V., in which M.T.J.H., and G.J.L.W. declare a financial interest. All other authors declare that they have no competing interests.</p> <h2>Author Contributions</h2> <p>L.X. and G.J.L.W. conceptualized the research. L.X. prepared protein samples and collected single-molecule data and analyzed data; M.T.J.H. analyzed data; L.X., M.T.J.H. and G.J.L.W. wrote and edited the manuscript; G.J.L.W. supervised the project; the manuscript is read, revised, and confirmed by all the listed authors.</p>
Multiple Parameter Replica Exchange Gaussian Accelerated Molecular Dynamics for Enhanced Sampling and Free Energy Calculation of Biomolecular Systems
Open the record for dataset details and reuse information.
Data Sets For: Heterogeneous Structure, Mechanisms of Counterion Exchange, and the Spacer Salt Effect in Complex Molten Salt Mixtures Including LaCl3
<p>Data Sets For: Heterogeneous Structure, Mechanisms of Counterion Exchange, and the Spacer Salt Effect in Complex Molten Salt Mixtures Including LaCl3</p>
Exploring the Black Box: Analyzing Explainable AI Challenges and Best Practices Through Stack Exchange Discussions
Open the record for dataset details and reuse information.
Exchange Rate Data for Ghana
<p>The data set includes daily closing foreign-exchange rates of Ghana Cedi to US Dollar (GHS/USD), Ghana Cedi to European Euro (GHS/EUR), Ghana Cedi to Nigerian Naira (GHS/NGN), Ghana Cedi to West African CFA franc (GHS/XOF), Ghana Cedi to Zambian Kwacha (GHS/ZMW) and Ghana Cedi to Congolese franc (GHS/CDF).The span from 11 July 2007 to 31 December 2021 except for the GHS/ZMW and GHS/CDF which ranges from 1 January 2013 to 31 December 2021 and 1 April 2010 to 31 December 2021 respectively. This date period was chosen because it corresponds to the introduction of the new Ghana Cedi by the Bank of Ghana, in July 2007. The Data was obtained from Google finance.</p>
Rapid microfluidic perfusion system enables controlling dynamics of intracellular pH regulated by Na+/H+ exchanger NHE1
<p>Dataset for manuscript titled "Rapid microfluidic perfusion system enables controlling dynamics of intracellular pH regulated by Na+/H+ exchanger NHE1."</p> <p>Version 2: additional data for Figure 2(e) and (f).</p>
Unraveling the Mechanism and Modulation of Activation Barriers in Uncatalyzed Anhydride Covalent Bond Exchange
<p><span>This folder contains the DFT-optimized geometries (in .xyz format together with the gas-phase energy, E) accompanying the paper</span></p> <p><span>"Unraveling the Mechanism and Modulation of Activation Barriers in Uncatalyzed Anhydride Covalent Bond Exchange"</span></p> <p><span>Where conformers occur, they are always named from the lowest Gibbs energy to the highest in ascending order from c1 (sometimes omitted), c2, c3, ...</span></p> <p><span>/MAA_and_PNA/ -- DFT structures from the study of anhydride exchange beween methacrylic anhydride (MAA) and 4-pentenoic anhydride (PNA)</span></p> <p><span><span> </span>|----/acid_catalysis/ -- DFT structures from M06-2X/def2-SVP level of theory optimization in gas phase for acid catalyzed mechanism</span></p> <p><span><span> </span>|----/gas_def2/ -- DFT structures from M06-2X/def2-SVP level of theory optimization in gas phase</span></p> <p><span><span> </span>|----/gas_def2_irc/ -- IRC movies of the TS for the concerted mechanism with and without acid at M06-2X/def2-SVP level of theory in gas phase</span></p> <p><span><span> </span>|----/gas_pople/ -- DFT structures from M06-2X/6-31G+(d) level of theory optimization in gas phase</span></p> <p><span><span> </span>|----/solv_opt/ -- DFT structures from SMD(CHCl3)-M06-2X/def2-SVP level of theory optimization in implicit chloroform solvent phase</span></p> <p><span>/UDC3/ -- DFT structures from the study of anhydride self-exchange beween UDC3 monomers, individual folders therein contains individual (un)substituted UDC3 systems</span></p> <p> </p>
Sensitive, Efficient and Portable Analysis of Molecular Exchange Processes by Hyperpolarized Ultrafast NMR
<p>Dataset for manuscript:</p> <p><a href="https://doi.org/10.1002/anie.202203957"><strong>Sensitive, Efficient and Portable Analysis of Molecular Exchange Processes by Hyperpolarized Ultrafast NMR </strong></a></p> <p> </p> <p>The uploaded archive contains:</p> <p>1. File Analysis.ipynb: Jupyter notebook with analysis and figure generation presented in the article<br> 2. UF-DEXSY experiment with mixing time 10ms: DEXSY/25<br> 3. UF-DEXSY experiment with mixing time 30ms: DEXSY/26<br> 4. UF-DEXSY experiment with mixing time 100ms: DEXSY/28<br> 5. Reference CPMG: CPMG/16<br> 6. Coil profile with yeast sample: UFProfile/4<br> 7. Coil profile with dopped water sample: UFProfile/101</p> <p> </p>
Chen et al (2021) Mesoscale and Submesoscale Shelf-Ocean Exchanges Initialize an Advective Marine Heatwave
<p>data and software for Chen et al (2021) "Mesoscale and Submesoscale Shelf-Ocean Exchanges Initialize an Advective Marine Heatwave" in Journal of Geophysical Research: Oceans</p>
Experimental and numerical study of a PCM solar air heat exchanger and its ventilation preheating effectiveness
<p>Dataset including experimental data and data for numerical validation. The corresponding figures can be found in the paper Experimental and numerical study of a PCM solar air heat exchanger and its ventilation preheating effectiveness.</p>
Experimental analysis of PCM heat exchanger in ventilated window system
<p>The dataset includes the published experimental data in the article Experimental analysis of PCM heat exchanger in ventilated window system. For the details of the data description please refer to the paper.</p> <p> </p>
Genetic variation in leaf traits and gas exchange response to vapor pressure deficit in two contrasting conifer species
<p>1. Mechanistically predicting the evolutionary response of tree species to climate change requires an understanding of genetic variation in relevant traits. Here we compared the phenotypic and genetic variation in the Leaf Economics Spectrum (LES) traits and the response of gas exchange to vapor pressure deficit (VPD) in lodgepole pine (Pico) and white spruce (Pigl), an early and a late successional species dominating the boreal forests of western Canada. 2. We measured gas exchange, foliar nitrogen, and lamina mass to area ratio in 697 app. 30-year-old trees in two field progeny trials. We analyzed the response of gas exchange rates to VPD using a novel quantitative genetic model, the function-valued trait approach. 3. Pico showed greater phenotypic variation in the LES traits and greater genetic variation in photosynthetic rate than Pigl, but the species showed no significant difference in their phenotypic correlations between the LES traits. Pico showed a less sensitive stomatal response to VPD than Pigl and no significant genetic variation in stomatal sensitivity. In contrast, Pigl showed a positive correlation between the genetic values of stomatal sensitivity to VPD and stomatal conductance under low VPD. 4. Our study region is projected to see an increase in VPD with climate change; the less sensitive and genetically diverse stomatal response to VPD in Pico could make this species more vulnerable to climate change-induced droughts. </p>
Madagascar Hissing Cockroach hemolymph PO2, PCO2, and gas exchange parameters
<p>This data set contains <em>in vivo </em>measurements of<em> </em>hemolymph PO<sub>2</sub> and PCO<sub>2</sub> made on Madagascar hissing cockroaches (<em>Gromphadorhina portentosa</em>) using implanted micro fiber optic sensors (optodes). In addition, rate of CO<sub>2</sub> release, ventilation frequency, and durations of the tri-phasic discontinuous gas exchange cycle associated with these measurements are also recorded. All measurements were performed while the cockroaches were breathing either normoxic and normocapnic air, hypoxic air (10 kPa PO<sub>2</sub>), or hypercapnic air (2 kPa PCO<sub>2</sub>) at 22 ºC.</p>
Figure files for Charge-noise spectroscopy of Si/SiGe quantum dots via dynamically-decoupled exchange oscillations
<p>This repository contains .fig (matlab) files corresponding to the figures in Charge-noise spectroscopy of Si/SiGe quantum dots via dynamically-decoupled exchange oscillations. The raw data are available from the corresponding author upon reasonable request.</p>
Ventilatory parameters measured in Madagascar hissing cockroaches during continuous gas exchange and DGCs
<p>This dataset is presented in the manuscript titled: 'Discontinuous gas exchange in Madagascar hissing cockroaches is not a consequence of hysteresis around a fixed PCO<sub>2</sub> threshold'; published in JEB. The primary purpose of this investigation was to test if discontinuous gas exchange cycles (DGCs) were caused by PCO<sub>2</sub> fluctuations around ventilatory setpoints. Madagascar hissing cockroaches were exposed to normoxic acapnia and treatments of either hypoxic acapnia, and normoxic hypercapnia, while displaying continious gas exchange, and DGCs. Hemolymph PO<sub>2 </sub>and PCO<sub>2</sub> were measured in conjunction with ventilatory frequency and VCO<sub>2 </sub>released. This data displays the changes in ventilatory parameters observed during ambient gas manipulations.</p>
Pd-exchanged BEA and CHA
<p>The data set contains:</p> <ul> <li>Nuclear repulsion energy: <ul> <li>xyz coordinates of CHA and BEA</li> <li>energies given in json file (CHA-NRE.json and BEA-NRE.jon)</li> </ul> </li> <li>Structures: <ul> <li>xyz coordinates of the DFT optimized structures of either Pd-exchanged zeolite (CHA or BEA) or proton compensating zeolite (also CHA and BEA)</li> <li>xyz coordinates are given for the full QM/MM atom and the QM atoms</li> </ul> </li> <li>energy.json: <ul> <li>the calculated DFT energy of the optimized structures</li> </ul> </li> <li>qm_region: <ul> <li>xyz coordinates of the optimized DFT structures at different number of atoms in the QM region</li> <li>data are given for both the full QM/MM atoms and the QM atoms</li> </ul> </li> <li>gas_traj: <ul> <li>xyz coordinates of the optimized DFT structures of various adsorbates on Pd-exchanged CHA</li> </ul> </li> </ul> <p>The nomenclature used to tabulate the data is as follow:</p> <ul> <li>zeolite name (CHA or BEA) - a number representing structure with a unique Al arrangement - adsorbate name (Pd+2, Pd+H+, Pd+, H+ or H+H+) - a number representing an initial position of the adsorbate - level of theory (GGA or hGGA) - type of calculations (opt for optimization and sp for single point calculation).</li> </ul>
Data for "Reactions Between Layer-Resolved Molecules Mediated by Dipolar Spin Exchange"
<p>Raw data for Figs. 1-4, S4</p>
OA eBook Usage Data Exchange Network Business Model Canvas
<p>This initial business model canvas was created to inform technical and governance roadmap discussions pertaining to the data exchange elements of the Developing a Data Trust for Open Access Ebook Usage project.</p>
Daily load patterns of six global exchanges as recorded by vwd/Infront Financial Technology
<p>This data set provides fine-granular statistics on trading traffic generated by six global exchanges over the course of two days in February 2019 for a set of representative feeds and recorded by the systems of vwd Vereinigte Wirtschaftsdienste GmbH (now known as Infront Financial Technology GmbH).</p> <p>Please note that these numbers represent only limited market segments of the actual exchange and the measured feeds might provide different products and instrument types.</p> <p>The exchanges are identified as AU = Sydney, FFM = Frankfurt am Main (GER), HK = Hong Kong (CN), Q = NASDAQ (USA), TK = Tokyo (JPN), UK = London (UK).</p> <p>The data set consists of six (6) files in comma-separated values (CSV) format with one tab as separator.</p> <p>Each file contains a list of timestamped (GMT+1) statistics that represent the update rate per second averaged to the granularity of one minute as received from the respective exchange at each point in time. Format: [UNIX timestamp] \t [updAvg].</p> <p>Please cite this conference paper when using this data:</p> <p>Frischbier, S., Paic, M., Echler, A., Roth, C. (2020). Managing the Complexity of Processing Financial Data at Scale - An Experience Report. In: Boy, G., Guegan, A., Krob, D., Vion, V. (eds) Complex Systems Design & Management. CSDM 2019. Springer, Cham. https://doi.org/10.1007/978-3-030-34843-4_2</p> <p> </p> <p> </p> <p> </p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.