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346 results for “functional integration”
Ribosomal protein S5b is essential for oogenesis and is required to maintain mitochondrial integrity and function in Drosophila melanogaster
GEO Series GSE121533. Drosophila melanogaster. 24 samples. Type: Other.
Example simulation showing spatial and temporal variations in surface carbon biomass of plankton functional groups during a Spring bloom as shown by a 3D hydrodynamic-biogeochemical model (FVCOM-ERSEM), with and without integration of the mixoplankton paradigm.
<p>The outputs are from simulations from using the FVCOM hydrodynamic model coupled to two different versions of ERSEM – (i) ERSEM and (ii) ERSEM-PB (the latter includes the implementation of the mixoplankton paradigm through integration of the 'Perfect Beast' PB model; Flynn and Mitra 2009 <em>Journal of Plankton Research</em>).</p> <p>The FVCOM domain was configured to represent Lyme Bay: a protected bay on the South Coast of England. This region is an important area for shellfish aquaculture. The domain was configured at 350 m – 5 km high-resolution, resolving sub-km scale dynamics in the area. A nested modelling approach of increasing model resolution was set up using two model domains. For the coupled hydrodynamic-biogeochemical model, a parent domain of 1.5 km – 10 km resolution was used to drive Lyme Bay model domain. The atmospheric forcing was provided by a 3-step downscaling of GFS global datasets to reach the 3 km of the final model domain using the Weather Research Forecast (WRF) model. Hydrodynamic boundary conditions are extracted from the European Copernicus Marine System North West European Shelf Forecast system. River flows were extracted from a National scale hydrology model run by the Center for Hydrology and Ecology in the UK. Simulations were initialised at Jan 1<sup>st</sup> 2005, and spun up for 3 months prior to the output of the data visualised in these videos. </p> <p>The 6 videos portray spatial and temporal variation of daily averaged surface carbon biomass (μgC L<sup>-1</sup>) during the month of April 2005 for the different plankton functional types (FTs) as follows:</p> <ul> <li>Video 1: all phytoplankton FTs in standard ERSEM grouped together. These thus include diatoms, nano-, pico- and micro- plankton; i.e., these simulations do not discriminate between phytoplankton and constitutive mixoplankton (CM).</li> <li>Video 2: phytoplankton FT in ERSEM-PB now considering only diatoms and picoplankton (i.e., cyanobacteria) only; CM are now included in Video 3 outputs.</li> <li>Video 3: all mixoplankton FTs grouped together in ERSEM-PB. These outputs thus include biomasses of micro-CM, nano-CM and NCM.</li> <li>Video 4: all zooplankton FTs grouped together in standard ERSEM. Thus, these include nanoflagellates, meso- and micro- zooplankton and thus includes the primary producing non-constitutive mixoplankton</li> <li>Video 5: zooplankton FT representing only the heterotrophic nano- and micro- zooplankton in ERSEM-PB.</li> <li>Video 6: spatio-temporal variability between the constitutive and non-constitutive mixoplankton functional groupings within FVCOM-ERSEM-PB. </li> </ul> <p>For further information about the mixoplankton paradigm, please see the following open access publications and references there in:</p> <p>Mitra A, Caron DA, Faure E, Flynn KJ, Leles SG, Hansen PJ, McManus GB, Not F, Gomes HR, Santoferrara L, Stoecker DK, Tillmann U (2023) <strong>The Mixoplankton Database – diversity of photo-phago-trophic plankton in form, function and distribution across the global ocean</strong>. <em>Journal of Eukaryotic Microbiology</em>, e12972. <a href="https://doi.org/10.1111/jeu.12972">https://doi.org/10.1111/jeu.12972</a></p> <p>Glibert PM, Mitra A (2022) <strong>From webs, loops, shunts, and pumps to microbial multitasking: evolving concepts of marine microbial ecology, the mixoplankton paradigm, and implications for a future ocean</strong>. <em>Limnology and Oceanography</em> 67: 585-597 <a href="https://doi.org.10.1002/lno.12018">https://doi.org.10.1002/lno.12018</a> </p> <p>Mitra A, Irigoien X (2022) <strong>Mixoplankton – Marine Organisms that break the rules</strong>. EU Researcher. <a href="https://issuu.com/euresearcher/docs/mixitin_eur28_h_res">https://issuu.com/euresearcher/docs/mixitin_eur28_h_res</a> </p> <p>Flynn KJ, Mitra A, Anestis K, Anschütz AA, Calbet A, et al. (2019) <strong>Mixotrophic protists and a new paradigm for marine ecology: where does plankton research go now?</strong> <em>Journal of Plankton Research</em> 41: 375-391 <a href="https://doi.org/10.1093/plankt/fbz026">https://doi.org/10.1093/plankt/fbz026</a></p>
RNA quality control by CCR4 safeguards chromatin integrity and centromere function in Arabidopsis [RNA-seq]
GEO Series GSE274191. Arabidopsis thaliana. 15 samples. Type: Expression profiling by high throughput sequencing.
Functional dissection of ovarian aging-associated genes NDUFS5 and UBE2L3 through integrated genomic analyses and validation
GEO Series GSE288033. Homo sapiens. 62 samples. Type: Expression profiling by high throughput sequencing.
Evaluation of the role of functional constraints on the integrity of an ultra conserved region in the genus Drosophila
GEO Series GSE31120. Drosophila melanogaster. 36 samples. Type: Expression profiling by array.
In vitro effects of paralytic shellfish toxins and lytic extracellu-lar compounds produced by Alexandrium strains on hemocyte integrity and function in Mytilus edulis.
<p>Data set from dose-response<em> in vitro</em> approaches</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.