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5,573 results for “optimality”

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dryad40/100

User preference optimization for control of ankle exoskeletons using sample efficient active learning

<p>A major challenge to the widespread success of augmentative exoskeletons is accurately adjusting the controller to provide cooperative assistance with their wearer. Often, the controller parameters are ``tuned'' to optimize a physiological or biomechanical objective. However, these approaches are resource-intensive, while typically only enabling optimization of a single objective. In reality, the exoskeleton user experience is derived from many factors, including comfort and stability, among others. This work introduces an approach to conveniently tune four parameters of the exoskeleton controller that maximize user preference. We use an evolutionary algorithm to recommend potential parameters, which are ranked by a neural network that is pre-trained with previously collected preference data. The controller parameters that have the highest preference ranking are provided to the exoskeleton, and the wearer provides feedback as forced-choice comparisons. Our approach was able to converge on controller parameters preferred by the wearer compared to randomized parameters with an accuracy of 88% on average. The result indicates that the proposed algorithm was able to identify users' preferences while requiring less than 50 queries to users. This work demonstrates user preference can be used to tune high-dimensional controller spaces easily and accurately, which shows the potential of translating lower-limb wearable technologies into our daily lives.</p>

opencc-zeroOct 2023View details →
zenodo40/100

Data for "On optimizing mass spectral library search and spectral alignment by weighting low-intensity peaks and m/z frequency"

<p>Data for <a href="https://github.com/enveda/weighting-spectral-similarity#on-optimizing-mass-spectral-library-search-and-spectral-alignment-by-weighting-low-intensity-peaks-and-mz-frequency">On optimizing mass spectral library search and spectral alignment by weighting low-intensity peaks and m/z frequency</a>.</p>

opencc-by-4.0Oct 2023View details →
zenodo40/100

Supplementary Datasets for "Genome-wide CRISPR off-target prediction and optimization using RNA-DNA interaction fingerprints"

<p>Supplementary Datasets for "Genome-wide CRISPR off-target prediction and optimization using RNA-DNA interaction fingerprints". The deposition contains training/testing&nbsp;datasets used in the article.</p>

opencc-by-4.0Oct 2023View details →
zenodo40/100

Data --- "Optimization of Convolutional Neural Network models for spatially coherent multi-site fire danger predictions"

<p>Data to reproduce the results of the manuscript entitled "Optimization of Convolutional Neural Network models for spatially coherent multi-site fire danger predictions" submitted to Geophysical Research Letters. The companion jupyter notebook can be found in DOI:&nbsp;<a href="https://doi.org/10.5281/zenodo.8387558">10.5281/zenodo.8387558</a></p>

opencc-by-4.0Oct 2023View details →
ClinicalTrials.gov40/100

Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial

ClinicalTrials.gov study NCT03149757. IPD Sharing: YES. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Optimizing Efficiency and Impact of Digital Health Interventions for Caregivers

ClinicalTrials.gov study NCT04986904. IPD Sharing: YES. Countries: 1. Publications: 3.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Code Blue Outcomes & Process Improvement Through Leadership Optimization Using Teleintensivists-Simulation

ClinicalTrials.gov study NCT03000829. IPD Sharing: YES. Countries: 1. Publications: 5.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Swab Testing to Optimize Pneumonia Treatment with Empiric Vancomycin

ClinicalTrials.gov study NCT06272994. IPD Sharing: YES. Countries: 1. Publications: 24.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Optimizing Function and Independence Through STRIDE

ClinicalTrials.gov study NCT03300336. IPD Sharing: YES. Countries: 1. Publications: 5.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Program Refinements to Optimize Model Impact and Scalability Based on Evidence

ClinicalTrials.gov study NCT03628287. IPD Sharing: NO. Countries: 1. Publications: 10.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov40/100

A Pharmacokinetic and Safety Study of Moxidectin to Identify an Optimal Dose for Treatment of Children 4 to 11 Years

ClinicalTrials.gov study NCT03962062. IPD Sharing: YES. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Optimizing Function and Independence Through iHI-FIVES

ClinicalTrials.gov study NCT03474380. IPD Sharing: YES. Countries: 1. Publications: 4.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

DOT Diary Optimization Pilot: A Pilot Study to Optimize the DOT Diary App to Measure PrEP Adherence

ClinicalTrials.gov study NCT03387462. IPD Sharing: YES. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon

ClinicalTrials.gov study NCT03951064. IPD Sharing: YES. Countries: 1. Publications: 2.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Start Time Optimization of Biologics in Polyarticular JIA

ClinicalTrials.gov study NCT02593006. IPD Sharing: YES. Countries: 2. Publications: 2.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

ClinicalTrials.gov study NCT00680901. IPD Sharing: YES. Countries: 23. Publications: 2.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Building an Optimal Hand Hygiene Bundle

ClinicalTrials.gov study NCT02223455. IPD Sharing: YES. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Safety, Tolerability, Efficacy and Optimal Dose Finding Study of BAF312 in Patients With Relapsing-remitting Multiple Sclerosis

ClinicalTrials.gov study NCT00879658. IPD Sharing: UNDECIDED. Countries: 12. Publications: 2.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov40/100

Vedolizumab Intravenous (IV) Dose Optimization in Ulcerative Colitis

ClinicalTrials.gov study NCT03029143. IPD Sharing: YES. Countries: 2. Publications: 1.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov40/100

Veteran Peer Coaches Optimizing and Advancing Cardiac Health

ClinicalTrials.gov study NCT02697422. IPD Sharing: YES. Countries: 1. Publications: 3.

controlledIPD-YESFeb 2026View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

ScienceDex for faculty

Your academic CV and NIH biosketch

Make your CV in your school's format and your NIH biosketch from it, then download both as Word files.