Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,041
datasets available to search
ShareScore release 0.9.0
Dataset results
1,041 results for “targeted therapy”
Targeting IL-21 to tumor-reactive T cells enhances memory T cell responses and anti-PD-1 antibody therapy
GEO Series GSE164093. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
CRISPR screening reveals targets to reprogram long-lived effector CD8+ T cells for cancer therapy. [RNA-Seq]
GEO Series GSE126071. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
The target antigen determines the mechanism of acquired resistance to T cell based therapies
GEO Series GSE210592. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
CD146 as a potent target for anti-vascular therapies in lung cancer brain metastasis
GEO Series GSE248935. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Inactivation of the splicing factor RBM10 limits EGFR targeted therapy response in EGFR mutant lung cancer
GEO Series GSE199240. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Determination of the tumor microenvironment remodeling by KRAS targeted therapy in pancreatic cancer
GEO Series GSE252834. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response
GEO Series GSE208253. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Resistance to PRMT5 Inhibitor Targeted Therapy in MCL
GEO Series GSE240726. Homo sapiens. 68 samples. Type: Expression profiling by high throughput sequencing; Other.
MiR-133b regulates the expression of the actin protein TAGLN2 during oocyte growth and maturation: a potential target for infertility therapy
GEO Series GSE57657. Homo sapiens. 2 samples. Type: Non-coding RNA profiling by array.
Blockade of the pro-fibrotic reaction mediated by the miR-143/-145 cluster enhances the responses to targeted therapy in melanoma
GEO Series GSE171883. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Expression profiling by array; Non-coding RNA profiling by high throughput sequencing.
LSD1 inhibition attenuates targeted therapy-induced lineage plasticity in BRAFV600E colorectal cancer
GEO Series GSE290028. Homo sapiens; Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
Intratumor heterogeneity of EGFR expression mediates targeted therapy resistance and formation of drug tolerant microenvironment
GEO Series GSE267515. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Targeting epigenetic regulation and post-translational modification with 5-Aza-2’ deoxycytidine and SUMO E1 inhibition Augments T Cell Receptor Therapy
GEO Series GSE267689. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Targeting YAP/TAZ-TEAD as a precision therapy approach in head and neck squamous cell carcinoma
GEO Series GSE277859. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer [ChIP-seq]
GEO Series GSE113092. Homo sapiens. 83 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeting thymidine phosphorylase as a potential therapy for bone loss associated periprosthetic osteolysis
GEO Series GSE171542. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
RNA sequencing data of paired parental and therapy resistant cancer cell lines transfected with negative control siRNA's or a pool of siRNA's targeting DNMT1, DNMT3A and DNMT3B
GEO Series GSE142586. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Divergent resistance mechanisms to HER2-targeted therapies in breast cancer
GEO Series GSE161423. Mus musculus; Homo sapiens. 64 samples. Type: Expression profiling by high throughput sequencing; Genome variation profiling by high throughput sequencing.
Anti-seed PNAs targeting multiple oncomiRs for brain tumor therapy
GEO Series GSE217366. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Comparing Neoantigen Cancer Vaccines and Immune Checkpoint Therapy Unveils an Effective Vaccine and Anti-TREM2 Macrophage-Targeting Dual Therapy [neoAgSpCD8Tcells]
GEO Series GSE276904. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.