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Dataset results
804 results for “wound healing”
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles
GEO Series GSE314229. Rattus norvegicus. 9 samples. Type: Expression profiling by high throughput sequencing.
Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing
GEO Series GSE186527. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Spatiotemporal Single-Cell Roadmap of Human Skin Wound Healing (Single-cell-Wound)
GEO Series GSE241132. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Reprogramming of epidermal keratinocytes by PITX1 transforms the cutaneous cellular landscape and promotes wound healing.
GEO Series GSE280088. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing; Other.
Single-cell RNA-sequencing of skin immune cells uncover a role for Angptl4-mediated ifi20b expression in monocyte cell fate differentiation during wound healing
GEO Series GSE186986. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
SFRP2 modulates functional phenotype transition and energy metabolism of macrophages during diabetic wound healing [RAW264.7 cells]
GEO Series GSE268759. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Monocyte/macrophage heterogeneity during skin wound healing in mice
GEO Series GSE203244. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Identification of Macrophage-Dependent Fcer1g+ Mesenchymal Cells as Key Regulators of Scar Formation in Wound Healing
GEO Series GSE280334. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype.
GEO Series GSE77382. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Spatiotemporal Single-Cell Roadmap of Human Skin Wound Healing (Spatial)
GEO Series GSE241124. Homo sapiens. 16 samples. Type: Other.
Evaporative cooling signals for wound healing in plants
GEO Series GSE293328. Arabidopsis thaliana. 9 samples. Type: Expression profiling by high throughput sequencing.
Angiogenin Released from ABCB5+ Stromal Precursors Improves Healing of Diabetic Wounds by Promoting Angiogenesis
GEO Series GSE181881. Homo sapiens; Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Data from: Effects of nicotine on corneal wound healing following acute alkali burn
Epidemiological studies have indicated that smoking is a pivotal risk factor for the progression of several chronic diseases. Nicotine, the addictive component of cigarettes, has powerful pathophysiological properties in the body. Although the effects of cigarette smoking on corneal re-epithelialization have been studied, the effects of nicotine on corneal wound healing-related neovascularization and fibrosis have not been fully demonstrated. The aim of this study was to evaluate the effects of chronic administration of nicotine on corneal wound healing following acute insult induced by an alkali burn. BALB/C female mice randomly received either vehicle (2% saccharin) or nicotine (100 or 200 μg/ml in 2% saccharin) in drinking water ad libitum. After 1 week, animals were re-randomized and the experimental group was subjected to a corneal alkali burn, and then nicotine was administered until day 14 after the alkali burn. A corneal alkali burn model was generated by placing a piece of 2 mm-diameter filter paper soaked in 1N NaOH on the right eye. Histopathological analysis and the expression level of the pro-angiogenic genes vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP9) revealed that chronic nicotine administration enhanced alkali burn-induced corneal neovascularization. Furthermore, the mRNA expression of the pro-fibrogenic factors α-smooth muscle actin (αSMA), transforming growth factor-β (TGF-β), and collagen α1 (Col1) was enhanced in the high-concentration nicotine-treated group compared with the vehicle group after corneal injury. Immunohistochemical analysis also showed that the αSMA-positive area was increased in chronic nicotine-treated mice after corneal alkali burn. An in vitro assay found that expression of the α3, α7, and β1 nicotinic acetylcholine receptor (nAChR) subunits was significantly increased by chemical injury in human corneal fibroblast cells. Moreover, alkali-induced fibrogenic gene expression and proliferation of fibroblast cells were further increased by treatment with nicotine and cotinine. The proliferation of such cells induced by treatment of nicotine and cotinine was reduced by inhibition of the PI3K and PKC pathways using specific inhibitors. In conclusion, chronic administration of nicotine accelerated the angiogenic and fibrogenic healing processes in alkali-burned corneal tissue.
Figure 2 from: Esad M, Popova M, Apostolova E, Bivolarska A (2024) Signal transduction in wound healing: The effects of plant-derived biologically active substances. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e117793
Figure 2 Content and effects of M. vulgare methanolic extract.
Figure 3 from: Esad M, Popova M, Apostolova E, Bivolarska A (2024) Signal transduction in wound healing: The effects of plant-derived biologically active substances. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e117793
Figure 3 Effects of V. Vinifera on wound healing.
Figure 1 from: Esad M, Popova M, Apostolova E, Bivolarska A (2024) Signal transduction in wound healing: The effects of plant-derived biologically active substances. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e117793
Figure 1 Inflammatory stage of early healing.
Figure 9 from: Abdullah E, Taha S, Sulaiman N, Ahmed M (2022) Impact of acacia arabica topical gel on skin wound healing: An experimental study. Pharmacia 69(1): 77-83. https://doi.org/10.3897/pharmacia.69.e72595
Figure 9 Inflammatory reaction during 14 days.
Figure 10 from: Abdullah E, Taha S, Sulaiman N, Ahmed M (2022) Impact of acacia arabica topical gel on skin wound healing: An experimental study. Pharmacia 69(1): 77-83. https://doi.org/10.3897/pharmacia.69.e72595
Figure 10 Granulation tissue reaction.
Figure 1 from: Abdullah E, Taha S, Sulaiman N, Ahmed M (2022) Impact of acacia arabica topical gel on skin wound healing: An experimental study. Pharmacia 69(1): 77-83. https://doi.org/10.3897/pharmacia.69.e72595
Figure 1 A 1 cm incision on skin B 5% Acacia gel on the incision.
Figure 11 from: Abdullah E, Taha S, Sulaiman N, Ahmed M (2022) Impact of acacia arabica topical gel on skin wound healing: An experimental study. Pharmacia 69(1): 77-83. https://doi.org/10.3897/pharmacia.69.e72595
Figure 11 Re-epithelialization score.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.