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16,682 results for “Lung.”
Supplementary material 1 from: Chen R, Shen T, Tsai K, Hu C (2016) Pericardial window operation for malignant pericardial effusion may have worse outcomes for lung cancer than the other cancers. Research Ideas and Outcomes 2: e8758. https://doi.org/10.3897/rio.2.e8758
Detailed statistical output by Stata/MP 13.1
Construction and clinical significance of prognostic risk markers based on cancer driver genes in lung adenocarcinoma
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raw data of BUB1B promotes gemcitabine resistance in lung adenocarcinoma by activating the PI3K/AKT signaling pathway
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HDCA fetal lung spatial proteomics images
<p>The images provided in this repository is published alongside <a href="https://doi.org/10.1101/2024.01.25.577163" target="_blank" rel="noopener noreferrer">this preprint</a> and <a href="https://github.com/CellProfiling/HDCA-FetalLung-SpatialProteomics" target="_blank" rel="noopener noreferrer">this code repository</a>. The preprint and github repository provide further metadata and analysis information. When using the images in this repository, please cite the preprint under DOI: <a href="https://doi.org/10.1101/2024.01.25.577163" target="_blank" rel="noopener noreferrer">https://doi.org/10.1101/2024.01.25.577163</a>.<span> </span></p>
MORPHOLOGICAL CHANGES IN THE LUNGS UNDER THE EFFECT OF ACUTE RADIATION IN EXPERIMENTAL STUDIES
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Cross Spatio-Temporal Pathology-based Lung Nodule Dataset
<p>We introduce a novel cross spatio-temporal lung nodule dataset based on pathological information, which effectively integrates rich multimodal information within the spatio-temporal dimension.</p>
Cross Spatio-Temporal Pathology-based Lung Nodule Dataset
<p>We introduce a novel cross spatio-temporal lung nodule dataset based on pathological information, which effectively integrates rich multimodal information within the spatio-temporal dimension.</p>
Figure 5. – Latimeria chalumnae. Specimen CCC 24 in The lungs of extinct and extant coelacanths: a morphological and histological review
Figure 5. – Latimeria chalumnae. Specimen CCC 24 (MNHN- ZA-AC-2012-19). SEM images of the small mineralized plates of the lung. A: Smooth and slightly glossy surface of the plate (white asterisk) with the layers of collagen fibres (white arrows). B: Detail of the collagenous bundles in the successive conjunctive layers. C: An osteocyte (white arrowhead) with its cytoplasmic extensions (white arrows). D: Broken margin of a plate, with the artefactual lumen in the centre of the plate (white asterisk), several collagenous layers (white arrow-heads) and a bulk of mineralized spherules (white arrows). Inset: detail of the bulk of mineralized spherules. Scale bars: A, D = 100 μm; B = 20 μm; C, inset D = 25 μm.
Figure 2. – A-E in The lungs of extinct and extant coelacanths: a morphological and histological review
Figure 2. – A-E: Latimeria chalumnae. CCC3 (MNHN-ZA- AC-2012-1) (A) and CCC79 (MNHN-ZA-AC-2012-26) (B-E). A: Photograph of three mineralized plates (black and white arrows) originally positioned on the external surface of the vestigial lung (vl). B-D: External views of three isolated mineralized plates. E: Internal view of a mineralized plate with demarcation between the mineralization field stained with alizarin red, and the non-min- eralized margin (black asterisk). F: †Axelrodichthys araripensis, "Josa collection" (specimen deposited at the Laboratoire of Pale- ontology, MNHN, Paris). Right lateral view showing the posterior portion of the lung with its imbricated ossified plates. Scale bars: A = 2.5 mm; B-D = 250 μm; E = 200 μm; F = 5 mm.
Figure 8. – A-D in The lungs of extinct and extant coelacanths: a morphological and histological review
Figure 8. – A-D: †Swenzia latimerae from the Jurassic of France (specimen MNHN.F.JRE47). SEM images of the bony plates of the lung. A: The bumpy reliefs on the surface correspond to the spheritic mineralization. The white asterisk localizes the detail of Fig. 8D. B: Detail of an osteocyte lacuna (white arrow) with one osteocytic canalicle (black arrow). C: Detail of a bulk of mineralized spherules (white arrowheads). D: Detail of some mineralized spherules. Scale bars: A = 50 μm; B, D = 10 μm; C = 20 μm.
Figure 1. – A in The lungs of extinct and extant coelacanths: a morphological and histological review
Figure 1. – A: †Macropoma mantelli Agassiz, 1835. Drawing of the left lateral view of the Cretaceous specimen NHMUK PV P 4219 (from Agassiz 1833-1844, Vol 2: Pl. 65A). The calcified lung (black arrow) occupied the whole length of the abdominal cavity. It is surrounded by imbricate ossified plates. B: †Macropoma lewesiensis (Mantell, 1822) (= †Macropoma mantelli). Reconstruction of the skeleton showing the ossified plates (black arrow) of the lung (after Forey, 1998: fig. 11.11). C: † Axelrodichthys araripensis. Left lateral view of specimen "Josa collection" MNHN, Paris) from the Cretaceous of Brazil showing the lung (white arrowhead) which occupied the whole length of the abdominal cavity. D: Latimeria chalumnae. Three-dimensional reconstruction of the specimen CCC22 (MNHN-ZA-AC-2012-18). In red: vestigial lung (white arrow); in yellow: digestive tract (black arrow-head); in green: fatty organ (black arrow) (from Cupello et al., 2017a: fig. 1a) E: Three-dimensional reconstruction of the lung surrounded by bony plates of L. chalumnae adult specimen CCC28 (MNHN-ZA-AC-2020-35.2). In yellow: oesophagus (oe); in white: small mineralized plates: in red: vestigial lung (vl) composed of its short anterior part and of its long residual cord (rc). (from Cupello et al., 2015: fig. 3c). Scale bars: A, C, D: 10 cm; B = 5 cm; E = 1 cm.
EPIDEMIOLOGICAL DESCRIPTION OF CHRONIC OBSTRUCTIVE LUNG DISEASE IN FERGONA VALLEY AND DETERMINATION OF ITS 10-YEAR CHANGING TREND
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Different lung microbiota community states are associated with pulmonary nontuberculous mycobacterial disease prognosis
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Fig. 2 in An Atlas Of Book Lung Fine Structure In The Order Scorpiones (Arachnida)
Fig. 2. Broteochactas delicatus (Karsch, 1879), 1 juv. ³ (AMNH), KOH-macerated cuticle: dorsal view of internal aspect of ventral mesosoma, showing location of book lungs.
Datasets accompanying Deep generative AI models analyzing circulating orphan non-coding RNAs enable accurate detection of early-stage non-small cell lung cancer
<p>These datasets accompany the manuscript "Deep generative AI models analyzing circulating orphan non-coding RNAs enable accurate detection of early-stage non-small cell lung cancer".</p> <p>The datasets include:</p> <ul> <li> <p><code>metadata.tsv.gz</code> Phenotype information of the samples</p> </li> <li> <p><code>mirna_counts.tsv.gz</code> MicroRNA count matrix (for data normalization)</p> </li> <li> <p><code>oncrna_counts.tsv.gz</code> oncRNA count matrix</p> </li> <li> <p><code>orion/</code> Ensemble of Orion models</p> </li> </ul>
Icariin inhibits lung adenocarcinoma progression through TP53-mediated ferroptosis
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Lung function abnormalities and its associated factors among stroke survivors
<p>It is a dataset of stroke suvivors who had their lung fucntion assessed usung spirometry</p>
Data from: Protective effect of Galectin-9 in murine model of lung emphysema: involvement of neutrophil migration and MMP-9 production
Purpose: Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow obstruction and pulmonary emphysema. Persistent inflammation and remodeling of the lungs and airways result in reduced lung function and a lower quality of life. Galectin (Gal)-9 plays a crucial role as an immune modulator in various diseases. However, its role in the pathogenesis of pulmonary emphysema is unknown. This study investigates whether Gal-9 is involved in pulmonary inflammation and changes in emphysema in a porcine pancreatic elastase (PPE)-induced emphysema model. Materials and Methods: Gal-9 was administered to mice subcutaneously once daily from 1 day before PPE instillation to day 5. During the development of emphysema, lung tissue and bronchoalveolar lavage fluid (BALF) were collected. Histological and cytological findings, concentrations of chemokines and matrix metalloproteinases (MMPs) in the BALF, and the influence of Gal-9 treatment on neutrophils were analyzed. Results: Gal-9 suppressed the pathological changes of PPE-induced emphysema. The mean linear intercept (Lm) of Gal-9-treated emphysema mice was significantly lower than that of PBS-treated emphysema mice (66.1 ± 3.3 µm vs. 118.8 ± 14.8 µm, respectively; p < 0.01). Gal-9 decreased the number of neutrophils and levels of MMP-9, MMP-2 and tissue inhibitor of metalloproteinases (TIMP)-1 in the BALF. The number of neutrophils in the BALF correlated significantly with MMPs levels. Interestingly, Gal-9 pretreatment in vitro inhibited the chemotactic activity of neutrophils and MMP-9 production from neutrophils. Furthermore, in Gal-9-deficient mice, PPE-induced emphysema progressed significantly compared with that in wild–type (WT) mice (108.7 ± 6.58 µm vs. 77.19 ± 6.97 µm, respectively; p < 0.01). Conclusions: These results suggest that Gal-9 protects PPE-induced inflammation and emphysema by inhibiting the infiltration of neutrophils and decreasing MMPs levels. Exogenous Gal-9 could be a potential therapeutic agent for COPD.
CircRPPH1 promotes cell proliferation, migration and invasion of non-small cell lung cancer (NSCLC) via the PI3K/AKT and JAK2/STAT3 signaling axes
<p>original numerical data before creating graphs</p>
The bradykinin-2 receptor antagonist, icatibant, improves lung function in patients with SARS-CoV2 associated ARDS - First results of a prospective off-label use patient-related observational study.
<p>SARS-CoV2-associated adult respiratory distress syndrome (COVID19-ARDS) frequently leads to fatal respiratory failure in COVID19. Currently, there is no curative treatment option for severe COVID19-ARDS other than mechanical ventilation therapy and extracorporal membrane oxygenation (ECMO). We investigated whether modification of the kallikrein-kinin system in vivo attenuates the progression of SARS-CoV2-induced ARDS. The aim of the study was to investigate the effect of blockade of the B2R on the course of COVID19-ARDS. In an observational study including 53 COVID19-ARDS patients, patients received the bradykinin-2-receptor antagonist (B2RAg) icatibant. After icatibant substitution, respiratory rate in COVID19-ARDS reduced by a maximum of 32% (24.9/min to 16.8/min) with a concomitant reduction in oxygen substitution by 59% (6.1 LO<sub>2</sub>/min to 2.5 LO<sub>2</sub>/min). The data show that the use of icatibant in the early phase of COVID19-ARDS is suitable to stabilize pulmonary gas exchange. Furthermore, early icatibant substitution seems to be able to reduce the rate of necessary invasive ventilation in COVID19-ARDS. Observational data suggest that inhibition of bradykinin signalling leads to stabilization of lung function in SARS-CoV2-associated ARDS. Further prospective placebo-controlled studies are needed to investigate the impact of the kallikrein-kinin system on the development of COVID19-ARDS in vivo.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.