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29,897 results for “activism”
Pan-cancer Aberrant Pathway Activity Analysis (PAPAA)
<p>Information about the dataset files:</p> <p>1) pancan_rnaseq_freeze.tsv.gz: Publicly available gene expression data for the TCGA Pan-cancer dataset. File: PanCanAtlas EBPlusPlusAdjustPANCAN_IlluminaHiSeq_RNASeqV2.geneExp.tsv was processed using script process_sample_freeze.py by Gregory Way et al as described in https://github.com/greenelab/pancancer/ data processing and initialization steps. [http://api.gdc.cancer.gov/data/3586c0da-64d0-4b74-a449-5ff4d9136611] [<a href="https://doi.org/10.1016/j.celrep.2018.03.046">https://doi.org/10.1016/j.celrep.2018.03.046</a>]</p> <p>2) pancan_mutation_freeze.tsv.gz: Publicly available Mutational information for TCGA Pan-cancer dataset. File: mc3.v0.2.8.PUBLIC.maf.gz was processed using script process_sample_freeze.py by Gregory Way et al as described in https://github.com/greenelab/pancancer/ data processing and initialization steps. [http://api.gdc.cancer.gov/data/1c8cfe5f-e52d-41ba-94da-f15ea1337efc] [https://doi.org/10.1016/j.celrep.2018.03.046] </p> <p>3) pancan_GISTIC_threshold.tsv.gz: Publicly available Gene- level copy number information of the TCGA Pan-cancer dataset. This file is processed using script process_copynumber.py by Gregory Way et al as described in https://github.com/greenelab/pancancer/ data processing and initialization steps. The files copy_number_loss_status.tsv.gz and copy_number_gain_status.tsv.gz generated from this data are used as inputs in our Galaxy pipeline. [https://xenabrowser.net/datapages/?cohort=TCGA%20Pan-Cancer%20(PANCAN)&removeHub=https%3A%2F%2Fxena.treehouse.gi.ucsc.edu%3A443] [<a href="https://doi.org/10.1016/j.celrep.2018.03.046">https://doi.org/10.1016/j.celrep.2018.03.046</a>]</p> <p>4) mutation_burden_freeze.tsv.gz: Publicly available Mutational information for TCGA Pan-cancer dataset mc3.v0.2.8.PUBLIC.maf.gz was processed using script process_sample_freeze.py by Gregory Way et al as described in https://github.com/greenelab/pancancer/ data processing and initialization steps. [https://github.com/greenelab/pancancer/][http://api.gdc.cancer.gov/data/1c8cfe5f-e52d-41ba-94da-f15ea1337efc] [https://doi.org/10.1016/j.celrep.2018.03.046]</p> <p>5) sample_freeze.tsv or sample_freeze_version4_modify.tsv: The file lists the frozen samples as determined by TCGA PanCancer Atlas consortium along with raw RNAseq and mutation data. These were previously determined and included for all downstream analysis All other datasets were processed and subset according to the frozen samples.[https://github.com/greenelab/pancancer/]</p> <p>6) cosmic_cancer_classification.tsv: Compendium of OG and TSG used for the analysis. Added additional genes from the cosmic database to volgelstein_cancer_classification.tsv [https://github.com/greenelab/pancancer/]</p> <p>7) CCLE_DepMap_18Q1_maf_20180207.txt.gz Publicly available Mutational data for CCLE cell lines from Broad Institute Cancer Cell Line Encyclopedia (CCLE) / DepMap Portal. [https://depmap.org/portal/download/api/download/external?file_name=ccle%2FCCLE_DepMap_18Q1_maf_20180207.txt]</p> <p>8) ccle_rnaseq_genes_rpkm_20180929_mod.tsv.gz: Publicly available Expression data for 1019 cell lines (RPKM) from Broad Institute Cancer Cell Line Encyclopedia (CCLE) / DepMap Portal. [https://depmap.org/portal/download/api/download/external?file_name=ccle%2Fccle_2019%2FCCLE_RNAseq_genes_rpkm_20180929.gct.gz]</p> <p>9) CCLE_MUT_CNA_AMP_DEL_binary_Revealer.tsv: Publicly available merged Mutational and copy number alterations that include gene amplifications and deletions for the CCLE cell lines. This data is represented in the binary format and provided by the Broad Institute Cancer Cell Line Encyclopedia (CCLE) / DepMap Portal. [https://data.broadinstitute.org/ccle_legacy_data/binary_calls_for_copy_number_and_mutation_data/CCLE_MUT_CNA_AMP_DEL_binary_Revealer.gct]</p> <p>10) GDSC_cell_lines_EXP_CCLE_names.tsv.gz Publicly available RMA normalized expression data for Genomics of Drug Sensitivity in Cancer(GDSC) cell-lines. File gdsc_cell_line_RMA_proc_basalExp.csv was downloaded. This data was subsetted to 389 cell lines that are common among CCLE and GDSC. All the GDSC cell line names were replaced with CCLE cell line names for further processing. [https://www.cancerrxgene.org/gdsc1000/GDSC1000_WebResources//Data/preprocessed/Cell_line_RMA_proc_basalExp.txt.zip]</p> <p>11) GDSC_CCLE_common_mut_cnv_binary.tsv.gz: A subset of merged Mutational and copy number alterations that include gene amplifications and deletions for common cell lines between GDSC and CCLE. This file is generated using CCLE_MUT_CNA_AMP_DEL_binary_Revealer.tsv and a list of common cell lines. </p> <p>12) gdsc1_ccle_pharm_fitted_dose_data.txt.gz: Pharmacological data for GDSC1 cell lines. [ftp://ftp.sanger.ac.uk/pub/project/cancerrxgene/releases/current_release/GDSC1_fitted_dose_response_15Oct19.xlsx]</p> <p>13) gdsc2_ccle_pharm_fitted_dose_data.txt.gz: Pharmacological data for GDSC2 cell lines. [ftp://ftp.sanger.ac.uk/pub/project/cancerrxgene/releases/current_release/GDSC2_fitted_dose_response_15Oct19.xlsx]</p> <p>14) compounds_of_interest.txt: list of pharmacological compounds tested for our analysis, taken from ftp://ftp.sanger.ac.uk/pub4/cancerrxgene/releases/release-8.1/screened_compounds_rel_8.1.csv. </p> <p>15) tcga_dictonary.tsv: list of cancer types used in the analysis. </p> <p>16) seg_based_scores.tsv: Measurement of total copy number burden, Percent of genome altered by copy number alterations. This file was used as part of the Pancancer analysis by Gregory Way et al as described in https://github.com/greenelab/pancancer/ data processing and initialization steps. [https://github.com/greenelab/pancancer/]</p> <p>17) GSE69822_pi3k_sign.txt: File with values assigned for tumor [1] or normal [-1] in given external samples (GSE69822)</p> <p>18) vlog_trans.csv: Variant stabilized log-transformed expression values in given external samples (GSE69822)</p> <p>19) path_rtk_ras_pi3k_genes.txt: File with the list of ERK/RAS/PI3K pathway genes used in the analysis. </p> <p>20) path_myc_genes.txt: File with the list of Myc pathway genes used in the analysis. (Sanchez-Vega, Francisco et al.)</p> <p>21) path_ras_genes.txt: File with the list of RAS pathway genes used in the analysis. (Sanchez-Vega, Francisco et al.)</p> <p>22) path_cell_cycle_genes.txt: File with the list of cell cycle pathway genes used in the analysis. (Sanchez-Vega, Francisco et al.)</p> <p>23) path_wnt_genes.txt: File with the list of WNT pathway genes used in the analysis. (Sanchez-Vega, Francisco et al.)</p> <p>24) GSE94937_rpkm_kras.csv: Expression values in given external samples (GSE94937)</p> <p>25) GSE94937_kras_sign.txt: File with values assigned for KRAS Mutant [1] or WT [-1] in given external samples (GSE94937)</p>
Carbene‐Catalyzed Activation of Remote Nitrogen Atoms of (benz)imidazole‐derived aldimines for Enantioselective Synthesis of Heterocycles
<p>This folder /xyz_structures/ contains the geometries (in .xyz format together with the gas-phase energy, E) accompanying the paper</p> <p>"Carbene‐Catalyzed Activation of Remote Nitrogen Atoms of (benz)imidazole‐derived aldimines for Enantioselective Synthesis of Heterocycles"</p> <p>citation: X. Yang, Y. Xie, J. Xu, S. Ren, B. Mondal, L. Zhou, W. Tian, X. Zhang, L. Hao, Z. Jin, Y. R. Chi, Angew. Chem. Int. Ed. 2021, 60, 7906.</p> <p>Where conformers occur, they are always named from the lowest Gibbs energy to the highest in ascending order from c1 (sometimes omitted), c2, c3, ...</p> <p>This folder has the following structure and they correspond to the raw data in the SI:</p> <p>/DFT_optimized_structures/ </p> <p> --> contains DFT-optimized structures for the computational study of the mechanism for the reaction between intermediates IV-3b/IV-3ac and isatin substrate 2b.</p> <p>/DI-AS_analysis/ </p> <p> --> structures along the IRC pathways for Si-ts1 (in subfolder /Si-ts1/) and Re-ts1 (in subfolder /Re-ts1/) taken for distortion interaction-activation strain (DI-AS) model analysis.</p> <p> --> structures along the IRC points are named p<num>.xyz where <num> denotes number of points along the IRC from the TS; fragments results from each point are denoted p<num>_f1.xyz and p<num>_f2.xyz. For example, the first point along the IRC is named p1.xyz and its component fragments are denoted p1_f1.xyz and p2_f2.xyz.</p>
Stress conditions and seismic activity around the rupture zone of the 2016 Kumamoto earthquake in Kyushu, southwest Japan
<p>This archive includes the dataset for the Stress conditions and seismic activity around the rupture zone of the 2016 Kumamoto earthquake in Kyushu, southwest Japan. Most of the datasets are arranged from the JMAhypocenter data. Text and xlsx type files are included. Some "read me" files are also in folders.</p> <p> </p>
A Magic Angle Spinning Activated 17O DNP Raser
<p>Raw data, processed spectra and the numerical integration code for the publication "A Magic Angle Spinning Activated 17O DNP Raser", DOI: 10.1021/acs.jpclett.0c03457. NMR data is in the Bruker TopSpin format. Numerical integration was performed in Matlab. </p>
Health profile of elderly users of a town public program of physical activity: a cross-sectional study
<p>This repository contains the full database generated in the study entitled "Health profile of elderly users of public physical activity programs in the city of Porto Alegre" (Hospital de Clínicas de Porto Alegre). This project was approved by the Institutional Review Board (IRB) in 2018 and carried out between 2018-2020.</p> <p> </p>
Inhibition mechanism and antibacterial activity of natural antibacterial agent citral on bamboo mold and its anti- mildew effect on bamboo
<p><span><span>Bamboo, a natural material, has been widely used in the fields of decoration, architecture and furniture. However, bamboo is easy to mildew and lose its use value. In this paper, inhibition mechanism and antibacterial activity of natural antibacterial agent citral on bamboo mold and its anti- mildew effect on bamboo were studied. The results showed that citral could change the shape of mycelium, destroy the integrity of mycelium structure, cell wall, and cell membrane structure, thereby causing leakage of nucleic acid, protein, and other substances in the cell, as well as destroy the pH balance of the inside and outside of the cell, to inhibit or kill mold. When the concentration of citral is 100mg/mL, the antibacterial rates of citral against <i>Penicillium citrinum </i>(PC), <i>Trichoderma viride</i> (TV), <i>Aspergillus niger</i> (AN) and a hybrid fungi group comprising PC, TV, and AN (Hun) were more than 100%. However, compared with the direct effect of citral on mold, the antibacterial property of bamboo treated with citral was significantly reduced, the mildew proof effect can be achieved only if the concentration of citral to treat bamboo is increased to more than 2 times of the concentration of citral directly acting on mold.</span></span></p>
Comparing three screen-based sedentary behaviours' effect upon adolescents' participation in physical activity: The ESSENS study
<p class="Arthurstyle1">Background: Literature focusing on the association between sedentary behaviours and physical activity has provided equivocal results and has been dominated by TV viewing as the indicator of sedentary behaviour. There is a need for more studies exploring the association between contemporary screen activities and physical activity among youth.</p> <p class="Arthurstyle1">Methods: A cross-sectional study including 742 adolescents was conducted in 2016. Data were collected at school through an online questionnaire. Regression analyses were used to explore the association between different screen-based sedentary behaviours and participation in physical activity.</p> <p class="Arthurstyle1">Results: The results showed that those with lower (vs higher) time spent on TV/movie streaming and electronic game playing both on weekdays and weekend days had significantly higher odds of participating in physical activity. There were no significant associations between socializing/surfing online both on weekdays and weekend days and physical activity in adjusted models.</p> <p class="Arthurstyle1">Conclusions: TV/movie streaming and electronic game playing during both weekdays and weekend days were significantly inversely related with participating in physical activity. Initiatives aimed at reducing screen-based sedentary activities might result in favourable effects on physical activity levels among adolescents.</p>
Cold-induced hyperphagia requires AgRP-neuron activation in mice
<p>To maintain energy homeostasis during cold exposure, the increased energy demands of thermogenesis must be counterbalanced by increased energy intake. To investigate the neurobiological mechanisms underlying this cold-induced hyperphagia, we asked whether agouti-related peptide (AgRP) neurons are activated when animals are placed in a cold environment and, if so, whether this response is required for the associated hyperphagia. We report that AgRP-neuron activation occurs rapidly upon acute cold exposure, as do increases of both energy expenditure and energy intake, suggesting the mere perception of cold is sufficient to engage each of these responses. We further report that silencing of AgRP neurons selectively blocks the effect of cold exposure to increase food intake but has no effect on energy expenditure. Together, these findings establish a physiologically important role for AgRP neurons in the hyperphagic response to cold exposure.</p>
Data supplement for "Phase-field crystal description of active crystallites: Elastic and inelastic collisions"
<p>This dataset contains data related to the publication:</p> <p>Lukas Ophaus and Johannes Kirchner and Svetlana V. Gurevich and Uwe Thiele, "Phase-field crystal description of active crystallites: Elastic and inelastic collisions" Chaos<strong> 30</strong>, 123149 (2020); <a href="https://doi.org/10.1063/5.0019426">https://doi.org/10.1063/5.0019426</a></p> <p>The set contains (i) all figures in pdf format and (ii) complete data files accompanied by python plot scripts for selected figures.</p> <p> </p>
Optimal allocation of law enforcement patrol effort to mitigate poaching activities
<p>Poaching is a global problem causing the decline of species worldwide. Optimizing the efficiency of ranger patrols to deter poaching activity at the lowest possible cost is crucial for protecting species with limited resources. We applied decision analysis and spatial optimization algorithms to allocate efforts of ranger patrols throughout a national park. Our objective was to mitigate poaching activity at or below management risk targets for the lowest monetary cost. We examined this tradeoff by constructing a Pareto efficiency frontier using integer linear programing. We used data from a ranger-based monitoring program in Nyungwe National Park, Rwanda. Our measure of poaching risk is based on dynamic occupancy models which account for imperfect detection of poaching activities. We found that in order to achieve a 5% reduction in poaching risk, 622 ranger patrol events (each corresponding to patrolling 1 km2 sites) were needed within a year at a cost of $49,760 USD. In order to attain a 60% reduction in poaching risk, 15,560 patrol events were needed at a cost of $1,244,800 USD. We evaluated the tradeoff between patrol cost and poaching risk based on our model by constructing a Pareto efficiency frontier and park managers found the solution for a 50% risk reduction to be a practical tradeoff based on funding constraints (comparable to recent years) and the diminishing returns between risk mitigation and cost. This expected reduction in risk required 8,558 patrol events per year at a cost of $684,640 USD. Our results suggest that optimal solutions could increase efficiency compared to the actual effort allocations from 2006 – 2016 in Nyungwe National Park (e.g., risk reductions of ~30% under recent budgets compared to ~50% reduction in risk under the optimal strategy). The modeling framework in this study took into account imperfect detection of poaching risk as well as the directional and conditional nature of ranger patrol events given the spatial adjacency relationships of neighboring sites and access points. Our analyses can help to improve the efficiency of ranger patrols, and the modeling framework can be broadly applied to other spatial conservation planning problems with conditional, multi-level, site selection.</p>
Data from: Dung beetle activity had no positive effect on nutrient concentration or performance of established rainforest seedlings
<p>All five datasets from this study correspond to field observations collected for seedlings of six tree species (<i>Brosimum alicastrum</i>, <i>Calophyllum brasiliense</i>, <i>Cymbopetalum baillonii</i>, <i>Diospyros digyna</i>, <i>Omphalea oleifera</i> and <i>Poulsenia armata</i>) in a tropical rainforest (Los Tuxtlas, Mexico). We estimated the concentrations of foliar nitrogen (N) and phosphorus (P), resource allocation (the ratio of biomass allocated to shoot vs root), seedling survival, and growth. Experimental seedlings were subject to three treatment levels: (a) feces added and beetles active, (b) feces added and beetles excluded, and (c) no feces added (and consequently no beetles active). We analyzed data at two levels: community (all plant species together) and individual species. For resource allocation (ESM_Dataset1_RootShoot) we weighed aerial parts (stem and leaves) and roots, separately, and calculated the root/shoot biomass ratio for each seedling. For foliar nutrients (ESM_Dataset2_FoliarNutrients) we obtained N and P concentrations using a Kjeldahl wet digestion and colorimetric analysis; for the analyses four outlier values were removed (for <em>Brosimum</em> one P value; for <i>Calophyllum</i> two P values and one N value). We analyzed foliar nutrients for all plant species. In the case of seedling survival (ESM_Dataset3_Survival) we registered seedling survival weekly during six weeks for <i>Cymbopetalum</i>, and during 26 weeks for the other five species. The response variable was the number of days elapsed until death; seedlings alive by the end of the experiment were included as right-censored data. For seedling growth in height (ESM_Dataset4_GrowthHeight; measured in all plant species except <i>Cymbopetalum</i>) we measured seedling height to the nearest centimeter every four or five weeks during 26 weeks. For this variable we calculated net growth in height (final height minus initial height). Finally, for the growth in the number of leaves (ESM_Dataset5_GrowthLeaves; measured in all plant species except <i>Cymbopetalum</i>) we counted the number of leaves lost and number of new leaves, every four or five weeks during 26 weeks; the response variable was the net growth in the number of leaves (final number of leaves minus initial number of leaves). All analyses were conducted in R. Detailed information about dataset structure and contents can be found in file ESM_Metadata.</p>
Aphicidal and antifeedant activity of Synandrospadix vermitoxicus extracts against Myzus persicae on potato plants
<p>Supplemental raw data and statistics of López-Isasmendi et al.</p>
Differential activation of c-Fos and Egr1 during development of the mouse visual cortex
<p>Critical periods (CP) in brain development are associated with profound changes in gene expression cascades. Here we examine the expression of the immediate early genes <i>c-Fos</i> and <i>Egr1</i> at different stages of mouse visual cortex (VC) development. Mice 11, 25, and 50 days of age were maintained under standard light-dark conditions, deprived of light for 5 days, or deprived of light for 5 days and then exposed to light for 90 min. Their brains were analyzed at PND16 (before the onset of the CP), PND30 (during the CP) and PND55 (after the CP) to determine the changes in the number of cells expressing <i>c-Fos</i> and <i>Egr1</i> in the binocular primary visual and primary somatosensory cortices. We found highly specific induction of <i>c-Fos </i>expression in the primary VC in response to light. We also observed transient cross-modal activation of <i>c-Fos</i> in the barrel field of the primary somatosensory cortex in response to light before and during the CP; such activation disappeared after the CP. Expression of <i>Egr1</i> was not induced by light in the VC before the CP, but was evident during and after the CP, although the induction was much less pronounced than that of <i>c-Fos</i>. Dynamic changes in <i>c-Fos</i> and <i>Egr1</i> expression may reflect their contribution to the VC plasticity during the CPs of postnatal brain development.</p>
Kinesin-1 activity recorded in living cells with a precipitating dye_FIB-SEM_data_2_part1
<p>Kinesin-1 activity recorded in living cells with a precipitating dye_FIB-SEM_data_2_part1</p>
Kinesin-1 activity recorded in living cells with a precipitating dye
<p>Raw Data and Protocols of the article 'Kinesin-1 activity recorded in living cells with a precipitating dye'.</p>
Kinesin-1 activity recorded in living cells with a precipitating dye_FIB-SEM_data_2_part2
<p>Kinesin-1 activity recorded in living cells with a precipitating dye_FIB-SEM_data_2_part2</p>
Quadriceps muscle power and optimal shortening velocity are inversely related to angiotensin converting enzyme activity in older men
<p>This dataset corresponds to the article titled "Quadriceps muscle power and optimal shortening velocity are inversely related to angiotensin converting enzyme activity in older men"</p>
Data from: On the scaling of activity in tropical forest mammals
<p>Activity range – the amount of time spent active per day – is a fundamental aspect contributing to the optimization process by which animals achieve energetic balance. Based on their size and the nature of their diet, theoretical expectations are that larger carnivores need more time active to fulfil their energetic needs than do smaller ones and also more time active than similar-sized non-carnivores. Despite the relationship between daily activity, individual range and energy acquisition, large-scale relationships between activity range and body mass among wild mammals have never been properly addressed. This study aimed to understand the scaling of activity range with body mass, while controlling for phylogeny and diet. We built simple empirical predictions for the scaling of activity range with body mass for mammals of different trophic guilds and used a phylogenetically controlled mixed model to test these predictions using activity records of 249 mammal populations (128 species) in 19 tropical forests (in 15 countries) obtained using camera traps. Our scaling model predicted a steeper scaling of activity range in carnivores (0.21) with higher levels of activity (higher intercept), and near-zero scaling in herbivores (0.04). Empirical data showed that activity ranges scaled positively with body mass for carnivores (0.061), which also had higher intercept value, but not for herbivores, omnivores and insectivores, in general, corresponding with the predictions. Despite the many factors that shape animal activity at local scales, we found a general pattern showing that large carnivores need more time active in a day to meet their energetic demands.</p>
Data from: Twelve years of repeated wild hog activity promotes population maintenance of an invasive clonal plant in a coastal dune ecosystem
Invasive animals can facilitate the success of invasive plant populations through disturbance. We examined the relationship between the repeated foraging disturbance of an invasive animal and the population maintenance of an invasive plant in a coastal dune ecosystem. We hypothesized that feral wild hog (Sus scrofa) populations repeatedly utilized tubers of the clonal perennial, yellow nutsedge (Cyperus esculentus) as a food source and evaluated whether hog activity promoted the long-term maintenance of yellow nutsedge populations on St. Catherine's Island, Georgia, United States. Using generalized linear mixed models, we tested the effect of wild hog disturbance on permanent sites for yellow nutsedge culm density, tuber density, and percent cover of native plant species over a 12-year period. We found that disturbance plots had a higher number of culms and tubers and a lower percentage of native live plant cover than undisturbed control plots. Wild hogs redisturbed the disturbed plots approximately every 5 years. Our research provides demographic evidence that repeated foraging disturbances by an invasive animal promote the long-term population maintenance of an invasive clonal plant. Opportunistic facultative interactions such as we demonstrate in this study are likely to become more commonplace as greater numbers of introduced species are integrated into ecological communities around the world.
Data from: Avoidance of windfarms by harbour seals is limited to pile driving activities
As part of global efforts to reduce dependence on carbon-based energy sources there has been a rapid increase in the installation of renewable energy devices. The installation and operation of these devices can result in conflicts with wildlife. In the marine environment, mammals may avoid wind farms that are under construction or operating. Such avoidance may lead to more time spent travelling or displacement from key habitats. A paucity of data on at-sea movements of marine mammals around wind farms limits our understanding of the nature of their potential impacts. Here, we present the results of a telemetry study on harbour seals Phoca vitulina in The Wash, south-east England, an area where wind farms are being constructed using impact pile driving. We investigated whether seals avoid wind farms during operation, construction in its entirety, or during piling activity. The study was carried out using historical telemetry data collected prior to any wind farm development and telemetry data collected in 2012 during the construction of one wind farm and the operation of another. Within an operational wind farm, there was a close-to-significant increase in seal usage compared to prior to wind farm development. However, the wind farm was at the edge of a large area of increased usage, so the presence of the wind farm was unlikely to be the cause. There was no significant displacement during construction as a whole. However, during piling, seal usage (abundance) was significantly reduced up to 25 km from the piling activity; within 25 km of the centre of the wind farm, there was a 19 to 83% (95% confidence intervals) decrease in usage compared to during breaks in piling, equating to a mean estimated displacement of 440 individuals. This amounts to significant displacement starting from predicted received levels of between 166 and 178 dB re 1 μPa(p-p). Displacement was limited to piling activity; within 2 h of cessation of pile driving, seals were distributed as per the non-piling scenario. Synthesis and applications. Our spatial and temporal quantification of avoidance of wind farms by harbour seals is critical to reduce uncertainty and increase robustness in environmental impact assessments of future developments. Specifically, the results will allow policymakers to produce industry guidance on the likelihood of displacement of seals in response to pile driving; the relationship between sound levels and avoidance rates; and the duration of any avoidance, thus allowing far more accurate environmental assessments to be carried out during the consenting process. Further, our results can be used to inform mitigation strategies in terms of both the sound levels likely to cause displacement and what temporal patterns of piling would minimize the magnitude of the energetic impacts of displacement.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.