Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
5,031
datasets available to search
ShareScore release 0.9.0
Dataset results
5,031 results for “MiRNA”
mRNA and miRNA expression changes at the neurovascular unit reveal a role for autophagy and DNA binding in the cerebral microvasculature of the ageing brain (mouse)
GEO Series GSE127709. Mus musculus. 10 samples. Type: Expression profiling by array.
Identification of Genes Related to Growth and Lipid Deposition from Transcriptome Profiles of Pig Muscle Tissue [miRNA]
GEO Series GSE93022. Sus scrofa. 4 samples. Type: Non-coding RNA profiling by high throughput sequencing.
miRNA expression profiles of HBE cells at different stages
GEO Series GSE26166. Homo sapiens. 2 samples. Type: Non-coding RNA profiling by array.
The miRNA microarray data after UVB exposure to human keratinocyte HaCaT cells
GEO Series GSE142534. synthetic construct; Homo sapiens. 2 samples. Type: Expression profiling by array.
Increased CLL Proliferation upon IgM stimulation is Sustained by the Up-regulation of miR-132 and miR-212: a Combined miRNA and Gene Expression Profiling Analysis and Correlation with Disease Progress
GEO Series GSE49696. Homo sapiens; synthetic construct. 56 samples. Type: Non-coding RNA profiling by array.
miRNA expression profiling divides follicular dendritic cell sarcomas into two groups, related to fibroblasts and myopericytomas or Castleman's disease
GEO Series GSE83994. Homo sapiens; synthetic construct. 58 samples. Type: Non-coding RNA profiling by array.
Identifying salt stress-responsive miRNAs and their targets in soybean (mRNA)
GEO Series GSE69569. Glycine max. 8 samples. Type: Expression profiling by high throughput sequencing.
Understanding the role of GLUT2 in dysglycemia associated with Fanconi-Bickel syndrome (NanoString miRNA profiling)
GEO Series GSE198677. Homo sapiens. 3 samples. Type: Other.
HOXA11-AS regulates NIPAL3 via hsa-miRNA-19a-3p, hsa-miR-141-3p and hsa-miR-140-5p in keloid fibroblast: stepwise bioinformatical screen for an integrated molecular network
GEO Series GSE191267. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
miRNA expression in the spleen of C57BL mice, p53-knockout C57BL mice, and NO2-knockout C57BL mice.
GEO Series GSE30218. Homo sapiens; Mus musculus. 41 samples. Type: Non-coding RNA profiling by array.
Small molecule mediated annotation of miRNAs regulating HCV hijacking of lipid pathways
GEO Series GSE73164. Homo sapiens. 9 samples. Type: Non-coding RNA profiling by array.
Sex-specific mRNA and miRNA expression data from Drosophila larvae, pupae and adults [miRNA]
GEO Series GSE57321. Drosophila melanogaster; synthetic construct. 12 samples. Type: Non-coding RNA profiling by array.
mRNA and miRNA expression profiling in mouse bronchoalveolar stem cells (BASC)
GEO Series GSE30437. Mus musculus. 8 samples. Type: Expression profiling by array; Other.
Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR pathway can originate from alteration in the functionality of the microRNA-mediated gene regulation being microRNAs (miRNAs) small noncoding RNA that act as post-transcriptional regulators of gene expression. In this study we gained insight into the role of miRNAs in the regulation of DDR to IR under microgravity a condition of weightlessness experienced by astronauts during space missions which could have a synergistic action on cells increasing the risk of radiation exposure. METHODOLOGY/PRINCIPAL FINDINGS: We analyzed miRNA expression profile of human peripheral blood lymphocytes (PBL) incubated for 4 and 24 h in normal gravity (1 g) and in modeled microgravity (MMG) during the repair time after irradiation with 0.2 and 2Gy of gamma-rays. Our results show that MMG alters miRNA expression signature of irradiated PBL by decreasing the number of radio-responsive miRNAs. Moreover let-7i* miR-7 miR-7-1* miR-27a miR-144 miR-200a miR-598 miR-650 are deregulated by the combined action of radiation and MMG. Integrated analyses of miRNA and mRNA expression profiles carried out on PBL of the same donors identified significant miRNA-mRNA anti-correlations of DDR pathway. Gene Ontology analysis reports that the biological category of Response to DNA damage is enriched when PBL are incubated in 1 g but not in MMG. Moreover some anti-correlated genes of p53-pathway show a different expression level between 1 g and MMG. Functional validation assays using luciferase reporter constructs confirmed miRNA-mRNA interactions derived from target prediction analyses. CONCLUSIONS/SIGNIFICANCE: On the whole by integrating the transcriptome and microRNome we provide evidence that modeled microgravity can affects the DNA-damage response to IR in human PBL.
Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant)
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and microRNA microarray in dauer larvae of Caenorhabditis elegans (C. elegans) that endured space xef xac x82ight environment and space radiations environment during 16.5-day Shenzhou-8 space mission were performed. In our study wild type and ced-1 mutant strains of C.elegans endured three conditions during shenzhou-8 spaceflight mission including spaceflight static condition(ss) spaceflight 1-g centrifugal condition(sc) and ground control condition(gc). Limited to the quantity of worm samples we performed technical-repeat test but not sample-repeat test.Accordingly xef xbc x8csix miRNA microarrays were performed.
Synergistic effects of space radiation and microgravity (miRNA WT and dys-mutant)
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and microRNA microarray in dauer larvae of Caenorhabditis elegans (C. elegans) that endured space xef xac x82ight environment and space radiations environment during 16.5-day Shenzhou-8 space mission were performed. In our study wild type and dys-1 mutant strains of C.elegans endured four conditions during shenzhou-8 spaceflight mission including spaceflight static condition(ss) spaceflight 1-g centrifugal condition(sc) ground control condition(gc) and no-transport control. Limited to the quantity of worm samples we performed technical-repeat test but not sample-repeat test. Accordingly eight miRNA microarrays were performed.
A miRNA Cassette Reprograms Smooth Muscle Cells into Endothelial Cells
GEO Series GSE181925. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
miRNA profile of duck duodenum mucosa damage caused by oxidative stress
GEO Series GSE237634. Anas platyrhynchos. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Identification of prognostic biomarkers in early stage squamous cell lung cancer (LUSC) by transcriptomic and miRNA profiling [sRNA-Seq]
GEO Series GSE230087. Homo sapiens. 18 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Integrated mRNA and miRNA expression profiling in blood reveals candidate biomarkers associated with endurance exercise in horse
GEO Series GSE73104. Equus caballus. 150 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.