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1,334 results for “Hematology”
Haploidentical Transplantation With CD3/CD19 Depleted Grafts in Patients With Hematologic Malignancies
ClinicalTrials.gov study NCT00202917. IPD Sharing: Not stated. Countries: 1. Publications: 1.
CXCR4-targeted PET/CT Imaging in Hematological Malignancies
ClinicalTrials.gov study NCT05255926. IPD Sharing: NO. Countries: 1. Publications: 3.
Hematological data of Batrachuperus tibetanus
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Fig. 2 in An external tag for fish: tagging effects in different fish size classes and its influence on growth performance and hematology of Lophiosilurus alexandri (Siluriformes: Pseudopimelodidae)
Fig. 2. Retention rate of tags for the different size classes of Lophiosilurus alexandri evaluated every 30 days for a period of 90 days. Means followed by different letters (upper- case between days and lowercase between sizes) differ significantly (p <0.05) by two-way ANOVA followed by Tukey test.
Fig. 4 in An external tag for fish: tagging effects in different fish size classes and its influence on growth performance and hematology of Lophiosilurus alexandri (Siluriformes: Pseudopimelodidae)
Fig. 4. Hematological parameters of tagged and untagged Lophiosilurus alexandri on the different days analyzed: a. Er. b. Leuk. c. TPP. d. MCV. e. Htc. Means followed by different capital letters differ significantly (p <0.05) between days by twoway ANOVA followed by Tukey test. Means with different lowercase letters differ significantly (p <0.05) between tagged and untagged fish by Student's t-test.
Fig. 3 in An external tag for fish: tagging effects in different fish size classes and its influence on growth performance and hematology of Lophiosilurus alexandri (Siluriformes: Pseudopimelodidae)
Fig. 3. Photograph of tagged Lophiosilurus alexandri. a. Large-size class animal after 90 days post-tagging. b. Small- -size class animal with wound caused after tag detachment during the experiment. Scale bar = 30 mm.
Fig. 1 in Hematological and biochemical characteristics during the transport of dog snapper Lutjanus jocu (Perciformes: Lutjanidae)
Fig. 1. Photomicrographs of a peripheral blood smear of Lutjanus jocu showing a corresponding sequence of images: a. Mature Erythrocyte (ME); b. Immature Erythrocyte (IE); c. Thrombocyte (T); d. Neutrophil (N); e. Lymphocyte (L); and f. Monocyte (M). Scale bars = 10 μm.
Data from: Impaired T Cell Responsiveness to Interleukin-6 in Hematological Patients with Invasive Aspergillosis
Invasive mold infections (IMI) are among the most devastating complications following chemotherapy and hematopoietic stem cell transplantation (HSCT), with high mortality rates. Yet, the molecular basis for human susceptibility to invasive aspergillosis (IA) and mucormycosis remain poorly understood. Herein, we aimed to characterize the immune profile of individuals with hematological malignancies (n = 18) who developed IMI during the course of chemotherapy or HSCT, and compared it to that of hematological patients who had no evidence of invasive fungal infection (n = 16). First, we measured the expression of the pattern recognition receptors pentraxin 3, dectin-1, and Toll-like receptors (TLR) 2 and 4 in peripheral blood of chemotherapy and HSCT recipients with IMI. Compared to hematological controls, individuals with IA and mucormycosis had defective expression of dectin-1; in addition, patients with mucormycosis had decreased TLR2 and increased TLR4 expression. Since fungal recognition via dectin-1 favors T helper 17 responses and the latter are highly dependent on activation of the signal transducer and activator of transcription (STAT) 3, we next used phospho-flow cytometry to measure the phosphorylation of the transcription factors STAT1 and STAT3 in response to interferon-gamma (IFN-γ) and interleukin (IL)-6, respectively. While IFN-γ/STAT1 signaling was similar between groups, naïve T cells from patients with IA, but not those with mucormycosis, exhibited reduced responsiveness to IL-6 as measured by STAT3 phosphorylation. Furthermore, IL-6 increased Aspergillus-induced IL-17 production in culture supernatants from healthy and hematological controls but not in patients with IA. Altogether, these observations suggest an important role for dectin-1 and the IL-6/STAT3 pathway in protective immunity against Aspergillus.
Data from: Effect of HIV and malaria parasites co-infection on immune-hematological profiles among patients attending anti-retroviral treatment (ART) clinic in Infectious Disease Hospital Kano, Nigeria
Background Human immunodeficiency virus (HIV) and malaria co-infection may present worse health outcomes in the tropics. Information on HIV/malaria co-infection effect on immune-hematological profiles is critical for patient care and there is a paucity of such data in Nigeria. Objective To evaluate immune-hematological profiles among HIV infected patients compared to HIV/malaria co-infected for ART management improvement. Methods This was a cross sectional study conducted at Infectious Disease Hospital, Kano. A total of 761 consenting adults attending ART clinic were randomly selected and recruited between June and December 2015. Participants' characteristics and clinical details including two previous CD4 counts were collected. Venous blood sample (4ml) was collected in EDTA tube for malaria parasite diagnosis by rapid test and confirmed with microscopy. Hematological profiles were analyzed by Sysmex XP-300 and CD4 count by Cyflow cytometry. Data was analyzed with SPSS 22.0 using Chi-Square test for association between HIV/malaria parasites co-infection with age groups, gender, ART, cotrimoxazole and usage of treated bed nets. Mean hematological profiles by HIV/malaria co-infection and HIV only were compared using independent t-test and mean CD4 count tested by mixed design repeated measures ANOVA. Statistical significant difference at probability of <0.05 was considered for all variables. Results Of the 761 HIV infected, 64% were females, with a mean age of ± (SD) 37.30 (10.4) years. Prevalence of HIV/malaria co-infection was 27.7% with Plasmodium falciparum specie accounting for 99.1%. No statistical significant difference was observed between HIV/malaria co-infection in association to age (p = 0.498) and gender (p = 0.789). A significantly (p = 0.026) higher prevalence (35.2%) of co-infection was observed among non-ART patients compared to (26%) ART patients. Prevalence of co-infection was significantly lower (20.0%) among cotrimoxazole users compared to those not on cotrimoxazole (37%). The same significantly lower co-infection prevalence (22.5%) was observed among treated bed net users compared to those not using treated bed nets (42.9%) (p = 0.001). Out of 16 hematology profiles evaluated, six showed significant difference between the two groups (i) packed cell volume (p = <0.001), (ii) mean cell volume (p = 0.005), (iii) mean cell hemoglobin concentration (p = 0.011), (iv) absolute lymphocyte count (p = 0.022), (v) neutrophil percentage count (p = 0.020) and (vi) platelets distribution width (p = <0.001). Current mean CD4 count cell/μl (349±12) was significantly higher in HIV infected only compared to co-infected (306±17), (p = 0.035). A significantly lower mean CD4 count (234.6 ± 6.9) was observed among respondents on ART compared to non-ART (372.5 ± 13.2), p<0.001, mean difference = -137.9). Conclusion The study revealed a high burden of HIV and malaria co-infection among the studied population. Co-infection was significantly lower among patients who use treated bed nets as well as cotrimoxazole chemotherapy and ART. Six hematological indices differed significantly between the two groups. Malaria and HIV co-infection significantly reduces CD4 count. In general, to achieve better management of all HIV patients in this setting, diagnosing malaria, prompt antiretroviral therapy, monitoring CD4 and some hematology indices on regular basis is critical.
An Analysis of Transcriptomic Burden Identifies Biological Progression Roadmaps for Hematological Malignancies and Solid Tumors
<p>Supplementary materials for review.</p>
CHANGES IN HEMATOLOGICAL AND BIOCHEMICAL BLOOD PARAMETERS OF CALVES WITH PNEUMOENTERITIS
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Figure 2 in Harbor seal pup dispersal and individual morphology, hematology, and contaminant factors affecting survival
Figure 2. Proportion of tags still transmitting by week post deployment separated by location of deployment: SF = San Francisco Bay, TB = Tomales Bay, and TMMC = The Marine Mammal Center. Tags that were permanently ashore were considered to be no longer transmitting.
Figure 4 in Harbor seal pup dispersal and individual morphology, hematology, and contaminant factors affecting survival
Figure 4. The relationship between total tag deployment time and dispersal distance per day for satellite tagged seal pups.
Fig. 1 in The influence of parasitism by Trypanosoma cruzi in the hematological parameters of the white ear opossum (Didelphis albiventris) from Campo Grande, Mato Grosso do Sul, Brazil
Fig. 1. Path analysis showing direct and indirect influences of infection by Trypanosoma cruzi in relation to anemia, infection responses, immune investment and body condition of Didelphis albiventris.
Early hematological indices as a predictor of placenta accreta
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Hematological indices in vaginitis
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Reduced Intensity Haploidentical Transplant for Hematological Malignancies
ClinicalTrials.gov study NCT01162096. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Cyclophosphamide for Hematopoietic Stem Cell Mobilization in Patients With a Hematologic Malignancy
ClinicalTrials.gov study NCT02139280. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase II Study of TPA Plus Dexamethasone & CMT in Hematologic Malignancies
ClinicalTrials.gov study NCT01009931. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies
ClinicalTrials.gov study NCT02566304. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.