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1,048 results for “aging effects”
Data from: Effects of aging on timing of hibernation and reproduction
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Data from: Effects of age and reproductive status on individual foraging site fidelity in a long-lived marine predator
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Effect of age on testis development in diamondback moth
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Data from: Sex-specific pathways of parental age effects on offspring lifetime reproductive success in a long-lived seabird
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Data from: The effects of aging on neuropil structure in mouse somatosensory cortex—A 3D electron microscopy analysis of layer 1
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Estimation of environmental, genetic and parental age at conception effects on telomere length in a wild mammal
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Data from: Age-related effects of chronic hantavirus infection on female host fecundity
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Effect of long-term aging on graphene oxide: structure and thermal decomposition
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The Immp2l mutation causes ovarian aging through ROS-wnt/β-catenin-estrogen (cyp19a1) pathway: preventive effect of melatonin
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Data from: The effects of age, sex, and habitat on body size and shape of the blackstripe topminnow, Fundulus notatus
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Male age alone predicts paternity success under sperm competition when effects of age and past mating effort are experimentally separated
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Data from: Effects of stand age, richness and density on productivity in subtropical forests in China
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Dynamic effects of insect herbivory and climate on tundra shrub growth: roles of browsing and ramet age
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Disentangling the effects of male age and mating history: contrasting effects of mating history on pre-copulatory mating behaviour and paternity success
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Effect of Hot-Wet Storage Aging on Mechanical Response of a Woven Thermoplastic Composite
<p>The effect of hot-wet storage aging on the mechanical response of a carbon fiber polyether ether ketone (PEEK)-matrix woven composite has been studied. A wide range of static loads and selected cyclic load tests on the interlaminar fatigue strength were performed. Static tests were conducted in batch mode, including on- and off-axis tension, compression, flexure, interlaminar shear strength (ILSS) and fracture tests in Modes I, II and I/II. Respective mechanical properties have been determined, indicating a degrading effect of aging on strength-related properties. The measured response in general, as well as the variance quantified by batch-mode test execution, indicated the appropriateness of the applied standards on the material under consideration, especially in the case of fracture tests. The material properties presented in the current work may provide a useful basis towards preliminary design with PEEK-based woven thermoplastic composites during service in aerospace applications.</p>
Effects of hot-wet storage aging, CNT-integration and damping layer interposition on static and fatigue interlaminar shear response of a UD Graphite/Epoxy material system
<p>The present work aims at experimental quantification of the effect of hot-wet storage aging on the static and<br> fatigue interlaminar shear response of three UD Graphite-Epoxy based material systems: a control laminate, a<br> CNT-treated laminate and a lamination including an embedded damping veil. In this context, specimens have<br> been fabricated and tested for determination of the interlaminar shear strength (ILSS) according to the relevant<br> ASTM standard, and the effects of the above mentioned constituents on the response of non-aged (RT) and aged<br> (HW) specimens have been investigated. The experimental data, presented in batch mode, indicated that aging<br> leads to severe degradation of the interlaminar shear strength and relevant fatigue endurance of all material<br> systems, whereas the CNT-treated laminate appeared to be the most sensitive configuration. In the case of nonaged specimens, CNT-treatment led to larger failure strains and a clear bilinear response, while all three material<br> systems exhibited similar values of interlaminar shear strength.</p>
Data from: Deleterious mutations show increasing negative effects with age in Drosophila melanogaster
<p><strong>Background</strong><br> In order for ageing to evolve in response to a declining strength of selection with age, a genetic architecture that allows for mutations with age-specific effects on organismal performance is required. Our understanding of how selective effects of individual mutations are distributed across ages is however poor. Established evolutionary theories assume that mutations causing ageing have negative late-life effects, coupled to either positive or neutral effects early in life. New theory now suggests evolution of ageing may also result from deleterious mutations with increasing negative effects with age, a possibility that has not yet been empirically explored.</p> <p><strong>Results</strong><br> To directly test how the effects of deleterious mutations are distributed across ages, we separately measure age-specific effects on fecundity for each of 20 mutations in <i>Drosophila melanogaster</i>. We find that deleterious mutations in general have a negative effect that increases with age, and that the rate of increase depends on how deleterious a mutation is early in life.</p> <p><b>Conclusions</b><br> Our findings suggest that ageing does not exclusively depend on genetic variants assumed by the established evolutionary theories of ageing. Instead, ageing can result from deleterious mutations with negative effects that amplify with age. If increasing negative effect with age is a general property of deleterious mutations, the proportion of mutations with the capacity to contribute towards ageing may be considerably larger than previously believed.</p>
An experimental test to separate the effects of male age and mating history on female mate choice
<p>Should females prefer older males as mates? Male survival to old age might indicate the presence of fitness-enhancing genes that increase offspring fitness. However, many correlational studies show that mating with older males can lower female fecundity, and even reduce offspring fitness due to epigenetic or germline mutation effects. One problem in quantifying female choice based on male age is that age is usually confounded with mating history. This begs a question: Do females choose males based on their age, or their mating history? The answer requires an experimental approach, but few such studies exist. Here we test if experimentally-induced variation in the mating history of old and young males (12 week difference in post-maturity age) affects female choice in the eastern mosquitofish (<i>Gambusia holbrooki</i>). To vary mating history, adult males were either allowed to freely mate with females for three weeks, or they only had visual contact with females. Immediately thereafter, we ran four-choice mating trials, using association time, to test the effects of male age and mating history (2x2 design) on male attractiveness. Females did not show a clear preference for males based on either characteristic. This was not due to a lack of female choice: females spent significantly more time with larger males. In addition, female choice was significantly repeatable across four trials: twice as a virgin, twice as a non-virgin. Finally, female mating status (virgin or non-virgin) did not affect her choice of mate, although virgin females spent significantly more time associating with test males.</p>
Data from: Interactive effects of social environment, age and sex on immune responses in Drosophila melanogaster
Social environments have been shown to have multiple effects on individual immune responses. For example, increased social contact might signal greater infection risk and prompt a prophylactic upregulation of immunity. This differential investment of resources may in part explain why social environments affect ageing and lifespan. Our previous work using Drosophila melanogaster showed that single-sex social contact reduced lifespan for both sexes. Here, we assess how social interactions (isolation or contact) affect susceptibility to infection, phagocytotic activity and expression of a subset of immune and stress related genes in young and old flies of both sexes. Social contact had a neutral, or even improved, effect on post-infection lifespan in older flies and reduced the expression of stress response genes in females, however it reduced phagocytotic activity. Together, these findings indicate that social contact in D. melanogaster does not have a predictable impact on immune responses and does not simply trade-off immune investment with lifespan.
The effect of age on non-reproductive division of labour in the tropical primitively eusocial wasp, Ropalidia cyathiformis
Division of labour among workers (non-reproductive division of labour), a characteristic feature of eusocial insects enables the efficient functioning of their colonies. In many advanced insect societies division of labour is based on age (age polyethism). Primitively eusocial insects however are believed to have a weak age polyethism. Here we investigated the role of age in non-reproductive division of labour in the tropical primitively eusocial wasp, Ropalidia cyathiformis and compared it with that in Ropalidia marginata, a congeneric species that exhibits relatively strong age polyethism. Age had a significant effect on the first performance of the four tasks studied; tasks were initiated in the sequence feed larva, build, bring food and bring building material. We measured task performance as the absolute frequency of tasks performed (FTP) and the probability of performing a task relative to other tasks (PTP) and age as absolute age in days since eclosion as well as relative age compared to nestmates. FTP varied significantly with both absolute and relative age, although absolute age explained more variance. PTP varied significantly with absolute age but not always with relative age. This is contrary to R. marginata, where more variation is explained by relative age than by absolute age. There was no trade-off between intranidal and extranidal tasks in R. cyathiformis unlike in R. marginata where the frequency of intranidal tasks decreased and that of extranidal tasks increased with age. We conclude that age polyethism is weak and less flexible in R. cyathiformis compared to that in R. marginata.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.