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1,041
datasets available to search
ShareScore release 0.9.0
Dataset results
1,041 results for “targeted therapy”
Single-cell profiling guided combinatorial immunotherapy for breast cancer resistance to Her2/neu and CDK4/6 targeted therapy
GEO Series GSE122336. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Targeting MDM4/MDM2 binding interface for reactivation of p53 in cancer therapy
GEO Series GSE62855. Homo sapiens. 24 samples. Type: Expression profiling by array.
Computational modeling integrating transcriptomic and vulnerability responses can predict suppressors of cell death as candidate targets for cancer therapy
GEO Series GSE255459. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
IKAROS facilitates antigen escape in the face of CD19- and CD22-targeted therapies for B-cell malignancies
GEO Series GSE225755. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies [RNA-seq]
GEO Series GSE249573. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Combined therapy with DR5- targeting antibody-drug conjugate and CDK inhibitors as a novel strategy for advanced MSS and MSI-H colorectal cancer
GEO Series GSE289746. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Targeting the ADPKD methylome using nanoparticle-mediated combination therapy
GEO Series GSE202065. Mus musculus. 12 samples. Type: Methylation profiling by high throughput sequencing.
Novel Properties of Side Population cells in Soft-tissue Sarcoma, and How They May Be Targeted to Develop Potential Therapies
GEO Series GSE24199. Homo sapiens. 8 samples. Type: Expression profiling by array.
Novel Targets for Diabetic Foot Ulcer Healing: A Transcriptomic Analysis by Negative Pressure Wound Therapy
GEO Series GSE272918. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeting the CBM signalosome induces Treg to prime the tumor environment for effective immune checkpoint therapy
GEO Series GSE129480. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
The brain tumor microenvironment primes metastatic cells for resistance to targeted therapies
GEO Series GSE174850. Mus musculus; Homo sapiens. 35 samples. Type: Expression profiling by high throughput sequencing.
Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy [RNA-Seq]
GEO Series GSE65761. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Acquired resistance to targeted therapy confers cross-resistance to immunotherapy
GEO Series GSE132443. Mus musculus. 236 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Acquired FGFR and FGF alterations confer resistance to estrogen receptor (ER) targeted therapy in ER+ metastatic breast cancer
GEO Series GSE153509. Homo sapiens. 647 samples. Type: Expression profiling by high throughput sequencing.
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer
GEO Series GSE106695. Homo sapiens. 125 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Divergent resistance mechanisms to HER2-targeted therapies in breast cancer (bulkRNA-Seq and Exome-Seq)
GEO Series GSE161420. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing; Genome variation profiling by high throughput sequencing.
Targeting innate immunity for antiviral therapy through small molecule agonists of the RLR pathway
GEO Series GSE74047. Homo sapiens. 48 samples. Type: Expression profiling by array.
Monoclonal Antibody Targeting Pear1 for Pulmonary Fibrosis Therapy [bulk RNA-seq]
GEO Series GSE183657. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer [CUT&RUN]
GEO Series GSE237769. Homo sapiens. 13 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Synergistic targeting of estrogen-receptor positive breast cancers by MDM2 inhibition in combination with endocrine therapy or CDK4/6 inhibition
GEO Series GSE140758. Homo sapiens. 29 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.