Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
5,016
datasets available to search
ShareScore release 0.9.0
Dataset results
5,016 results for “THERAPEUTICS”
EMT-driven plasticity prospectively increases cell-cell variability to promote therapeutic adaptation in breast cancer
GEO Series GSE263731. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Whole-blood transcriptome profiling reveals signatures of metformin and its therapeutic response
GEO Series GSE153792. Homo sapiens. 34 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic targeting of the pre-metastatic stage in human brain metastasis
GEO Series GSE110495. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.
Development of New Therapeutic Combinations for Ovarian Cancer Using Genetically Defined, Syngeneic Organoid Platform
GEO Series GSE147276. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Xeno-free cultured Mesenchymal Stromal Cells release Extracellular Vesicles with a “therapeutic” miRNA cargo ameliorating cartilage inflammation in vitro
GEO Series GSE209585. Homo sapiens. 8 samples. Type: Non-coding RNA profiling by array.
Circadian regulator REV-ERBα is a master regulator of tumor lineage plasticity and an effective therapeutic target [ChIP-Seq]
GEO Series GSE295844. Homo sapiens. 33 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Multi-level omics analysis of dystrophin loss and therapeutic restoration in a murine model [microRNA]
GEO Series GSE64419. synthetic construct; Mus musculus. 11 samples. Type: Non-coding RNA profiling by array.
Modeling Fanconi Anemia pathogenesis and therapeutics using integration-free patient iPSCs [RNA-seq]
GEO Series GSE57826. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Discovery and Evaluation of Biomarkers for Triple-Negative Breast Cancer Subtypes Uncovers Patient Stratification and Targeted Therapeutic Strategies
GEO Series GSE300385. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer
GEO Series GSE236500. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Functional Genomics Screen with Pooled shRNA Library and Gene Expression Profiling with Extracts of Azadirachta indica Identify Potential Pathways for Therapeutic Targets in Head and Neck Squamous Cel
GEO Series GSE125021. Homo sapiens. 24 samples. Type: Expression profiling by array.
Imidazole propionate is a driver and therapeutic target in atherosclerosis [scRNA-seq]
GEO Series GSE298392. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic activation of plasmacytoid DC drives IFNAR-dependent therapeutic differentiation of AML [RNAseq IFNAR KO tumor cells]
GEO Series GSE198114. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
SETD2 Loss Creates A Permissive Epigenetic Landscape that Promotes Kidney Cancer Metastasis and Engenders Therapeutic Vulnerabilities
GEO Series GSE146583. Mus musculus; Homo sapiens. 50 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq]
GEO Series GSE110571. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor
GEO Series GSE118164. Mus musculus. 82 samples. Type: Other; Genome variation profiling by genome tiling array; Expression profiling by array.
Epigenetic modulation of γ-globin expression as a new therapeutic approach for sickle cell disease
GEO Series GSE283100. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Targeting mTORC2-Dependent AKT/FOXO1/RNF125 Signaling Exploits a Therapeutic Vulnerability in c-MET-Activated and β-catenin-Mutated Hepatocellular Carcinoma [SNU449]
GEO Series GSE314956. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets [RNA-Seq_AML]
GEO Series GSE71686. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic Targeting of the p300/CBP Bromodomain Enhances the Efficacy of Immune Checkpoint Blockade Therapy
GEO Series GSE291279. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.