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2,849 results for “Adiposity”
Brown adipose tissue PET-MR after fructose and glucose intervention
<p>Includes the data and MATLAB functions used to produce the manuscript: "High-fructose feeding suppresses cold-stimulated brown adipose tissue glucose uptake in young men independently of changes in thermogenesis and the gut microbiome"</p>
Adipose-derived stromal cells preserve pancreatic islet function in a transplantable 3D bioprinted scaffold
<p><span>Intra-portal islet transplantation is the method of choice for treatment of insulin dependent type 1 diabetes, but its outcome is hindered by limited islet survival due to the immunological and metabolic stress post transplantation. Adipose-derived stromal cells (ASCs) promise to improve significantly the islet micro-environment but an efficient long-term delivery method has not been achieved. We therefore explore the potential of generating ASC enriched islet transplant structure by 3D bioprinting. Here, we fabricate a double-layered 3D bioprinted scaffold for islets and ASCs by using alginate-nanofibrillated cellulose bioink. We demonstrate the diffusion properties of the scaffold and report that human ASCs increase the islet viability, preserve the endocrine function, and reduce pro-inflammatory cytokines secretion <em>in vitro</em>. Intraperitoneal implantation of the ASCs and islets in 3D bioprinted scaffold improve the long-term function of islets in diabetic mice. Our data reveals an important role for ASCs on the islet micro-environment. We suggest a novel cell therapy approach of ASCs combined with islets in a 3D structure with a potential for clinical beta cell replacement therapies at extrahepatic sites. </span></p>
Spectral flow cytometric tracking of mitochondria transfer in adipose tissue by age and diet
<p>Unmixed fcs files for the stromal vascular fraction of epididymal (eWAT), inguinal (iWAT), and brown adipose tissue (BAT) in <em>mtD2<sup>F/+</sup>AdipoqCre<sup>+/-</sup></em> and different ages or diets. </p> <p>For a breakdown of samples and code, please see: <a href="https://github.com/ncborcherding/mtD2">https://github.com/ncborcherding/mtD2</a>. The full github repository at time of manuscript acceptance is also in the Zenodo repository under <strong>mtD2_GitHubRepo.zip</strong>.</p> <p><strong>Antibody Panel: </strong></p> <table align="center"> <tbody> <tr> <td> <p><strong>Laser</strong></p> </td> <td> <p><strong>Channel</strong></p> </td> <td> <p><strong>Antigen</strong></p> </td> <td> <p><strong>Fluorophore</strong></p> </td> <td> <p><strong>Final Dilution Factor</strong></p> </td> <td> <p><strong>Vendor</strong></p> </td> <td> <p><strong>Clone</strong></p> </td> <td> <p><strong>Catalog Number</strong></p> </td> </tr> <tr> <td> <p>Violet</p> </td> <td> <p>V1</p> </td> <td> <p>SiglecF</p> </td> <td> <p>BV 421</p> </td> <td> <p>1:400</p> </td> <td> <p>BD Biosciences</p> </td> <td> <p>E50-2440</p> </td> <td> <p>562681</p> </td> </tr> <tr> <td> </td> <td> <p>V2</p> </td> <td> <p>CD44</p> </td> <td> <p>Super Bright 436</p> </td> <td> <p>1:300</p> </td> <td> <p>eBioscience</p> </td> <td> <p>IM7</p> </td> <td> <p>62-044-180</p> </td> </tr> <tr> <td> </td> <td> <p>V3</p> </td> <td> <p>CD11b</p> </td> <td> <p>Pacific Blue</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>M1/70</p> </td> <td> <p>101224</p> </td> </tr> <tr> <td> </td> <td> <p>V5</p> </td> <td> <p>IL-33R⍺-biotin</p> </td> <td> <p>n/a</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>DIH9</p> </td> <td> <p>145308</p> </td> </tr> <tr> <td> </td> <td> <p>V5</p> </td> <td> <p>Streptavidin (2°)</p> </td> <td> <p>BV 480</p> </td> <td> <p>1:300</p> </td> <td> <p>BD Horizon</p> </td> <td> <p>n/a</p> </td> <td> <p>564876</p> </td> </tr> <tr> <td> </td> <td> <p>V7</p> </td> <td> <p>MHC-II (I-A/I-E)</p> </td> <td> <p>BV 510</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>M5/114.15.2</p> </td> <td> <p>107636</p> </td> </tr> <tr> <td> </td> <td> <p>V8</p> </td> <td> <p>Ly6C</p> </td> <td> <p>BV 570</p> </td> <td> <p>1:400</p> </td> <td> <p>BioLegend</p> </td> <td> <p>HK1.4</p> </td> <td> <p>128030</p> </td> </tr> <tr> <td> </td> <td> <p>V10</p> </td> <td> <p>KLRG1</p> </td> <td> <p>BV 605</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>2F1/KLRG1</p> </td> <td> <p>138419</p> </td> </tr> <tr> <td> </td> <td> <p>V11</p> </td> <td> <p>F4/80</p> </td> <td> <p>BV 650</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>BM8</p> </td> <td> <p>123149</p> </td> </tr> <tr> <td> </td> <td> <p>V13</p> </td> <td> <p>Ly6G</p> </td> <td> <p>BV 711</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>1A8</p> </td> <td> <p>127643</p> </td> </tr> <tr> <td> </td> <td> <p>V14</p> </td> <td> <p>CD3</p> </td> <td> <p>BV 750</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>17A2</p> </td> <td> <p>100249</p> </td> </tr> <tr> <td> </td> <td> <p>V15</p> </td> <td> <p>CD206</p> </td> <td> <p>BV 785</p> </td> <td> <p>1:200</p> </td> <td> <p>BioLegend</p> </td> <td> <p>C068C2</p> </td> <td> <p>141729</p> </td> </tr> <tr> <td> <p>Blue</p> </td> <td> <p>B1</p> </td> <td> <p>mtDendra2</p> </td> <td> <p>n/a</p> </td> <td> <p>n/a</p> </td> <td> <p>n/a</p> </td> <td> <p>n/a</p> </td> <td> <p>n/a</p> </td> </tr> <tr> <td> </td> <td> <p>B2</p> </td> <td> <p>TCRb</p> </td> <td> <p>AF 488</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>H57-597</p> </td> <td> <p>109215</p> </td> </tr> <tr> <td> </td> <td> <p>B3</p> </td> <td> <p>CD8</p> </td> <td> <p>Spark Blue 550</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>53-6.7</p> </td> <td> <p>100780</p> </td> </tr> <tr> <td> </td> <td> <p>B8</p> </td> <td> <p>CD45</p> </td> <td> <p>PerCP</p> </td> <td> <p>1:200</p> </td> <td> <p>BioLegend</p> </td> <td> <p>30-F11</p> </td> <td> <p>103130</p> </td> </tr> <tr> <td> </td> <td> <p>B9</p> </td> <td> <p>CD71</p> </td> <td> <p>PerCP-Cy5.5</p> </td> <td> <p>1:200</p> </td> <td> <p>BioLegend</p> </td> <td> <p>RI7217</p> </td> <td> <p>113816</p> </td> </tr> <tr> <td> </td> <td> <p>B10</p> </td> <td> <p>NKp46</p> </td> <td> <p>PerCP-eFluor710</p> </td> <td> <p>1:200</p> </td> <td> <p>eBioscience</p> </td> <td> <p>29A1.4</p> </td> <td> <p>46-3351-82</p> </td> </tr> <tr> <td> <p>Green</p> </td> <td> <p>YG1</p> </td> <td> <p>TCRgd</p> </td> <td> <p>PE</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>GL3</p> </td> <td> <p>118108</p> </td> </tr> <tr> <td> </td> <td> <p>YG3</p> </td> <td> <p>CD64</p> </td> <td> <p>PE/Dazzle 594</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>X54-5/7.1</p> </td> <td> <p>139320</p> </td> </tr> <tr> <td> </td> <td> <p>YG4</p> </td> <td> <p>CD4</p> </td> <td> <p>PE/Fire 640</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>GK1.5</p> </td> <td> <p>100482</p> </td> </tr> <tr> <td> </td> <td> <p>YG5</p> </td> <td> <p>CD62L</p> </td> <td> <p>PE-Cyanine5</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>MEL-14</p> </td> <td> <p>104410</p> </td> </tr> <tr> <td> </td> <td> <p>YG7</p> </td> <td> <p>CD11c</p> </td> <td> <p>PE-Cyanine5.5</p> </td> <td> <p>1:300</p> </td> <td> <p>eBioscience</p> </td> <td> <p>N418</p> </td> <td> <p>35-0114-82</p> </td> </tr> <tr> <td> </td> <td> <p>YG9</p> </td> <td> <p>CD25</p> </td> <td> <p>PE/Cyanine7</p> </td> <td> <p>1:200</p> </td> <td> <p>BioLegend</p> </td> <td> <p>PC61</p> </td> <td> <p>102016</p> </td> </tr> <tr> <td> <p>Red</p> </td> <td> <p>R1</p> </td> <td> <p>CD9</p> </td> <td> <p>APC</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>MZ3</p> </td> <td> <p>124812</p> </td> </tr> <tr> <td> </td> <td> <p>R2</p> </td> <td> <p>CD127</p> </td> <td> <p>AF 647</p> </td> <td> <p>1:200</p> </td> <td> <p>BioLegend</p> </td> <td> <p>A7R34</p> </td> <td> <p>135020</p> </td> </tr> <tr> <td> </td> <td> <p>R3</p> </td> <td> <p>CD19</p> </td> <td> <p>Spark NIR 550</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>6D5</p> </td> <td> <p>115568</p> </td> </tr> <tr> <td> </td> <td> <p>R4</p> </td> <td> <p>CD90.2</p> </td> <td> <p>AF 700</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>30-H12</p> </td> <td> <p>105320</p> </td> </tr> <tr> <td> </td> <td> <p>R5</p> </td> <td> <p>CD5</p> </td> <td> <p>BUV 737</p> </td> <td> <p>1:300</p> </td> <td> <p>BD Horizon</p> </td> <td> <p>53-7-3</p> </td> <td> <p>612809</p> </td> </tr> <tr> <td> </td> <td> <p>R6</p> </td> <td> <p>Viability dye</p> </td> <td> <p>Zombie NIR</p> </td> <td> <p>1:1,000</p> </td> <td> <p>BioLegend</p> </td> <td> <p>n/a</p> </td> <td> <p>423106</p> </td> </tr> <tr> <td> </td> <td> <p>R7</p> </td> <td> <p>NK1.1</p> </td> <td> <p>APC/Fire 750</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>PK136</p> </td> <td> <p>108752</p> </td> </tr> <tr> <td> </td> <td> <p>R8</p> </td> <td> <p>B220</p> </td> <td> <p>APC/Fire 810</p> </td> <td> <p>1:300</p> </td> <td> <p>BioLegend</p> </td> <td> <p>RA3-6B2</p> </td> <td> <p>103278</p> </td> </tr> </tbody> </table> <p> </p>
Small Toy Adipose TPM Expression Dataset
<p>Small TPM expression of genes in the adipose (subcutaneous). Original data is from GTEX V8 on TPM counts of genes in the adipose.</p>
Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells (Rotator Cuff Tear)
ClinicalTrials.gov study NCT02298023. IPD Sharing: Not stated. Countries: 1. Publications: 42.
Efficacy of Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis.
ClinicalTrials.gov study NCT03379168. IPD Sharing: NO. Countries: 1. Publications: 24.
Treatment of Early Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells
ClinicalTrials.gov study NCT03956719. IPD Sharing: NO. Countries: 1. Publications: 8.
Injection of Autologous Adipose-derived Stromal Vascular Fraction in the Finger of Systemic Sclerosis Patients
ClinicalTrials.gov study NCT03060551. IPD Sharing: NO. Countries: 1. Publications: 1.
Safety and Efficacy Study of Serostim® Human Immunodeficiency Virus-Associated Adipose Redistribution Syndrome
ClinicalTrials.gov study NCT01077960. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Effects of b3-Adrenergic Receptor Agonists on Brown Adipose Tissue
ClinicalTrials.gov study NCT01783470. IPD Sharing: NO. Countries: 1. Publications: 1.
STYLE -- A Trial of Cell Enriched Adipose For Androgenetic Alopecia
ClinicalTrials.gov study NCT02503852. IPD Sharing: NO. Countries: 1. Publications: 2.
Visceral Adiposity and Diabetes: Translating Form to Function Using Imaging
ClinicalTrials.gov study NCT02833415. IPD Sharing: YES. Countries: 1. Publications: 6.
Retrospective Results of Micronized Adipose Tissue in Patients With Interstitial Cystitis
ClinicalTrials.gov study NCT07104981. IPD Sharing: NO. Countries: 1. Publications: 3.
Growth and Adiposity in Newborns: The Influence of Prenatal Docosahexaenoic Acid (DHA) Supplementation
ClinicalTrials.gov study NCT03310983. IPD Sharing: Not stated. Countries: 1. Publications: 2.
The Project ATA: Adipose Tissue & Adipokines
ClinicalTrials.gov study NCT05758311. IPD Sharing: NO. Countries: 1. Publications: 3.
Changes in Adiposity, Metabolic Measures From Atypicals to Aripiprazole
ClinicalTrials.gov study NCT00205660. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Immunophenotyping of Fresh Stromal Vascular Fraction From Adipose Derived Stem Cells (ADSC) Enriched Fat Grafts
ClinicalTrials.gov study NCT01771913. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Microfragmented Adipose Tissue Versus Platelet-rich Plasma for Knee Osteoarthritis: a Randomized Comparative Trial
ClinicalTrials.gov study NCT04351087. IPD Sharing: NO. Countries: 1. Publications: 16.
Fish Oils and Adipose Inflammation Reduction
ClinicalTrials.gov study NCT02010359. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Use of Concentrated Endogenous Autologous Adipose Stromal Cells in Fat Grafts for Craniofacial Trauma
ClinicalTrials.gov study NCT01633892. IPD Sharing: UNDECIDED. Countries: 1. Publications: 7.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.