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50 results for “Anaphylaxis”
Observation Periods and Biphasic Reaction Risk Factors in Pediatric Emergency Anaphylaxis Cases
ClinicalTrials.gov study NCT07231393. IPD Sharing: NO. Countries: 0. Publications: 4.
Murine anaphylaxis to food requires cysteinyl leukotriene-mediated absorption of allergens in the gut
GEO Series GSE261022. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Integrative transcriptomic analysis in human and mouse models of anaphylaxis identifies upregulation of cell movement, migration and neuroinflammatory signalling pathway
GEO Series GSE215184. Homo sapiens; Mus musculus. 115 samples. Type: Expression profiling by high throughput sequencing.
1) Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts & 2) Epidermal ABHD12B-driven atypical acylceramide safeguards
GEO Series GSE262558. Mus musculus. 4 samples. Type: Other.
Data from: Identification of children with anaphylaxis at low risk of receiving acute inpatient therapies
Objective: Opportunity exists to reduce unnecessary hospitalizations for children with anaphylaxis given wide variation in admission rates across U.S. emergency departments (EDs). We sought to identify children hospitalized with anaphylaxis at low risk of receiving epinephrine and other acute inpatient therapies, as these patients may be candidates for ED discharge rather than inpatient hospitalization. Methods: We conducted a single-center retrospective cohort study of children 1–21 years of age hospitalized with anaphylaxis from 2009 to 2016. Acute inpatient therapies included intramuscular (IM) or racemic epinephrine, bronchodilators, fluid boluses, vasopressors, non-invasive ventilation, or intubation. We derived age-specific (pre-verbal [<36 months] vs. verbal [≥ 36 months]) prediction rules using recursive partitioning to identify children at low risk of receiving acute inpatient therapies. Results: During the study period 665 children were hospitalized for anaphylaxis, of whom 108 (16.2%) received acute inpatient therapies. The prediction rule for patients < 36 months (no wheezing, no cardiac involvement [hypotension or wide pulse pressure]) had a sensitivity of 90.5% (CI 69.6–98.8%) and a negative predictive value of 98.3% (CI 94.1–99.8%) for identifying children at low risk of receipt of acute inpatient therapies during hospitalization. For children ≥ 36 months, the prediction rule (no wheezing, no cardiac involvement, presence of gastrointestinal symptoms) had a sensitivity of 90.8% (CI 82.7–96.0%) and a negative predictive value of 92.4% (CI 85.6–96.7%). Conclusions: We derived age specific prediction rules for children hospitalized with anaphylaxis at low risk of receiving epinephrine and other acute inpatient therapies. These children may be candidates for ED discharge rather than inpatient hospitalization.
Health Literacy Among Caregivers of Children With IgE-mediated Allergy With Risk of Anaphylaxis
ClinicalTrials.gov study NCT04475003. IPD Sharing: NO. Countries: 1. Publications: 0.
The Metabolomics of Anaphylaxis
ClinicalTrials.gov study NCT01666275. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Protocol of Reintroduction of Beta-lactams in Children at Low Risk of Anaphylaxis.
ClinicalTrials.gov study NCT03553251. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Post-Marketing Safety Study in Japan of Shock and Anaphylaxis After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA-1273 COVID-19 Vaccine in Persons in at High Risk of Severe COVID-1
ClinicalTrials.gov study NCT05894499. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Desensitization of Human Mast Cells: Mechanisms and Potential Utility for Preventing Anaphylaxis
ClinicalTrials.gov study NCT00868842. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Advanced Multimodal Wireless Vital Signs Monitoring for Patients With Asthma and Anaphylaxis
ClinicalTrials.gov study NCT04360213. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Perioperative Anaphylaxis in Patients Attending University Hospitals (Egypt - UK).
ClinicalTrials.gov study NCT03393091. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Satisfaction of Patient With Anaphylaxis in the Use of a Medical Device
ClinicalTrials.gov study NCT02854969. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study About the Use of Omalizumab in the Treatment of Food Allergy and Anaphylaxis
ClinicalTrials.gov study NCT07027163. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Metabolomics of Anaphylaxis to Immunotherapy
ClinicalTrials.gov study NCT01666288. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Utility of Serum Tryptase in the Diagnosis of Shrimp- Induced Anaphylaxis
ClinicalTrials.gov study NCT01619605. IPD Sharing: Not stated. Countries: 1. Publications: 0.
FMXIN002 in Patients at Risk of Anaphylaxis
ClinicalTrials.gov study NCT07045701. IPD Sharing: NO. Countries: 1. Publications: 0.
Mechanisms of Anaphylaxis
ClinicalTrials.gov study NCT03182491. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of Medical Care and Patient's Knowledge About the Behavior to Take on Secondary Prevention of Anaphylaxis
ClinicalTrials.gov study NCT03953482. IPD Sharing: YES. Countries: 1. Publications: 0.
Murine anaphylaxis to food requires cysteinyl leukotriene-mediated absorption of allergens in the gut.
GEO Series GSE285568. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.