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92 results for “B vitamin”
B Vitamin Status in Premature and Small for Gestational Age(SGA) Infants
ClinicalTrials.gov study NCT01201005. IPD Sharing: Not stated. Countries: 1. Publications: 3.
The Effect of Alpha Lipoid Acid and Vitamin B Preparation on Diabetic Polyneuropathy in Type 2 Diabetes Mellitus Patient
ClinicalTrials.gov study NCT06568185. IPD Sharing: NO. Countries: 1. Publications: 0.
Correlation Between Vitamin D and B Regulatory Cell in Pregnancy
ClinicalTrials.gov study NCT04105881. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
VITRO-Trial. B Vitamins and the Secondary Prevention of Venous Thrombosis
ClinicalTrials.gov study NCT00314990. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy and Safety in the Combination of Celecoxib / Pregabalin / Vitamin B for Low Back Chronic Pain
ClinicalTrials.gov study NCT06516094. IPD Sharing: NO. Countries: 1. Publications: 11.
Vitamin D, Omega-3, and Combination Vitamins B, C and Zinc Supplementation for the Treatment and Prevention of COVID-19
ClinicalTrials.gov study NCT04828538. IPD Sharing: Not stated. Countries: 1. Publications: 6.
The Effects of Vitamin B-6 and Coenzyme Q10 Status on Oxidative Stress, Antioxidant Capacities, and Inflammatory Responses in Patients With Liver Cancer
ClinicalTrials.gov study NCT01964001. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Evaluating the Impact of B Vitamin Supplementation (Soloways™) on Homocysteine and LDL-C Levels in Patients With MTHFR, MTR, and MTRR Polymorphisms.
ClinicalTrials.gov study NCT06163443. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Dietary Riboflavin (Vitamin B-2) and Cornea Cross-Linking
ClinicalTrials.gov study NCT03095235. IPD Sharing: NO. Countries: 1. Publications: 2.
Vitamin B Complex and Diabetic Nephropathy in Type 1 Diabetes
ClinicalTrials.gov study NCT03594240. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
An Intervention Study to Investigate the Effect of B-vitamin Supplementation for 2-years on Bone Health
ClinicalTrials.gov study NCT03892395. IPD Sharing: NO. Countries: 1. Publications: 1.
WENBIT - Western Norway B Vitamin Intervention Trial
ClinicalTrials.gov study NCT00354081. IPD Sharing: Not stated. Countries: 1. Publications: 36.
The Analgesic Efficacy of Vitamin B Complex in Critically Ill Obstetrics After Caesarean Section
ClinicalTrials.gov study NCT06446830. IPD Sharing: NO. Countries: 1. Publications: 4.
Effect of 1 Year Vitamin D or D Plus B-vitamins on Bone Markers in Elderly People (KnoVIB)
ClinicalTrials.gov study NCT02586181. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Role of Carnosine in Combination With Vitamin B Complex in Preventing the Progression of Diabetic Neuropathy in Type 2 Diabetes Patients
ClinicalTrials.gov study NCT05422352. IPD Sharing: NO. Countries: 1. Publications: 10.
Vitamin D Regulation of Gut Specific B Cells and Antibodies Targeting Gut Bacteria in Inflammatory Bowel Disease
ClinicalTrials.gov study NCT04828031. IPD Sharing: Not stated. Countries: 1. Publications: 9.
The dose makes the poison: feeding of antibiotic-treated winter honey bees, Apis mellifera, with probiotics and b-vitamins
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Data from: Paternal B vitamin intake is a determinant of growth, hepatic lipid metabolism and intestinal tumor volume in female Apc1638N mouse offspring
Background The importance of maternal nutrition to offspring health and risk of disease is well established. Emerging evidence suggests paternal diet may affect offspring health as well. Objective In the current study we sought to determine whether modulating pre-conception paternal B vitamin intake alters intestinal tumor formation in offspring. Additionally, we sought to identify potential mechanisms for the observed weight differential among offspring by profiling hepatic gene expression and lipid content. Methods Male Apc1638N mice (prone to intestinal tumor formation) were fed diets containing replete (control, CTRL), mildly deficient (DEF), or supplemental (SUPP) quantities of vitamins B2, B6, B12, and folate for 8 weeks before mating with control-fed wild type females. Wild type offspring were euthanized at weaning and hepatic gene expression profiled. Apc1638N offspring were fed a replete diet and euthanized at 28 weeks of age to assess tumor burden. Results No differences in intestinal tumor incidence or burden were found between male Apc1638N offspring of different paternal diet groups. Although in female Apc1638N offspring there were no differences in tumor incidence or multiplicity, a stepwise increase in tumor volume with increasing paternal B vitamin intake was observed. Interestingly, female offspring of SUPP and DEF fathers had a significantly lower body weight than those of CTRL fed fathers. Moreover, hepatic trigylcerides and cholesterol were elevated 3-fold in adult female offspring of SUPP fathers. Weanling offspring of the same fathers displayed altered expression of several key lipid-metabolism genes. Hundreds of differentially methylated regions were identified in the paternal sperm in response to DEF and SUPP diets. Aside from a few genes including Igf2, there was a striking lack of overlap between these genes differentially methylated in sperm and differentially expressed in offspring. Conclusions In this animal model, modulation of paternal B vitamin intake prior to mating alters offspring weight gain, lipid metabolism and tumor growth in a sex-specific fashion. These results highlight the need to better define how paternal nutrition affects the health of offspring.
The impact of energy releasing B-vitamin intake on indices of obesity and cardiac function: a cross-sectional study
<p><strong>(1)</strong> Deficiencies in B7, B6, B9, and B12 lead to energy metabolism disruption, which induces the production of reactive oxygen species, inflammation, and lipogenesis.<sup>7</sup> <strong>(2)</strong> Reduced levels of B1, B2, B3, and B6 levels are associated with increased risk of metabolic syndrome, which is considered one of the major cases of obesity.<sup>6</sup> <strong>(3)</strong> Decreased levels of B1 and B2 are correlated with increased body mass index (BMI). <strong>(4) </strong>B6 regulates the expression of peroxisome proliferator-activated receptor gamma (PPARg) target genes, which play a key role in adipocyte gene expression and adipogenesis.<sup>40</sup> <strong>(5)</strong> Decreased B1, B3 and B6 concentrations are significantly correlated with increased risk of insulin resistance, metabolic dysfunction and obesity.<sup>41</sup> <strong>(6)</strong> B vitamins have a fundamental role in the lipid and lipoprotein metabolism cascade. Therefore, quantitative or qualitative defects in B vitamins will negatively impact the metabolism of lipid derivatives.<sup>35</sup> <strong>(7)</strong> B2 plays a vital role in energy-expenditure adipocyte gene regulation at the epigenetic level.<sup>42</sup> <strong>(8) </strong>Increased body weight leads to the reduction of vitamin B6 levels by inducing systemic oxidative stress, which leads to stimulation of adipocytokines dysregulation. </p>
The impact of energy releasing B-vitamin intake on indices of obesity and cardiac function: a cross-sectional study
<p>(1) B3 intake leads to decreased serum levels of low-density lipoprotein cholesterol (LDL), very low-density lipoprotein cholesterol (VLDL), and triglycerides (TG). Also, increased levels of high-density lipoprotein cholesterol (HDL).20 (2) Vitamins B2, B6, B9, and B12 have a vital role in homocysteine demethylation into methionine, which leads to decreased risk of atherosclerosis. 14, 20 (3) Decreased levels of folate intake lead to decreased DNA-methylation, which has been detected in atherosclerotic lesions,43 also B6 is associated with reduced risk of metabolic syndrome.6 (4) Low levels of B1, B3, and B6 were associated with increased insulin resistance, metabolic dysfunction, and increased risk of atherosclerosis, obesity, metabolic syndrome, diabetes, and cardiovascular disease.11, 38</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.