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323
datasets available to search
ShareScore release 0.9.0
Dataset results
323 results for “Binding specificity”
Specific mutations in the cholesterol-binding site of APP alter its processing and favor the production of shorter, less toxic Aβ peptides.
<p>Mass Spectrometry data of Abeta secreted peptides from HEK293 stable clones expressing APP or APPK28A treated or not with methylbetacyclodextrin-cholesterol.</p>
Identification of a HTT-specific binding motif in DNAJB1 essential for suppression and disaggregation of HTT
<p>Underlying data of the<em> in silico</em> work performed in this study. </p> <p>1. i-Tasser predictions for HTTExon1Q<sub>48 </sub></p> <p>2. HDOCK results of DNAJB1-HTTExon1Q<sub>48 </sub>docking</p> <p>3. TIGER2h structures and trajectories. The original data and filtered trajectories for the individual clusters</p> <p>4. MD Simulation structures and trajectories for DNAJB1 protein variants alone and as complexes with HTTExon1Q<sub>48.</sub></p>
Data from: Positive selection underlies the species-specific binding of P. falciparum RH5 to human basigin
Open the record for dataset details and reuse information.
RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific
GEO Series GSE215198. synthetic construct. 667 samples. Type: Expression profiling by array.
Genome-Wide Specificity of DNA-Binding, Gene Regulation, and Chromatin Remodeling by TALE- and CRISPR/Cas9-Based Transcription Factors
GEO Series GSE68341. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors
GEO Series GSE13684. Schizosaccharomyces pombe; Saccharomyces cerevisiae. 24 samples. Type: Expression profiling by array.
Sequence variation within similar cis-elements promotes context-specific functions of two Drosophila GA-binding transcription factors (protein binding microarray data set)
GEO Series GSE110653. Drosophila melanogaster. 2 samples. Type: Genome binding/occupancy profiling by array.
Specific binding sites on Rhesus rotavirus capsid protein dictates the method of endocytosis inducing the murine model of biliary atresia
GEO Series GSE267721. Mus musculus. 6 samples. Type: Expression profiling by array.
Locus-specific paramutation in Zea mays is maintained by a chromodomain helicase DNA-binding 3 protein controlling development and male gametophyte function
GEO Series GSE158990. Zea mays. 5 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Multiple physiological roles of both specific and non-specific DNA binding modes of HU protein in Escherichia coli
GEO Series GSE175465. Escherichia coli. 12 samples. Type: Expression profiling by high throughput sequencing.
Dynamic analysis of gene expression and genome wide transcription factor binding during lineage-specification of multipotent progenitors [ER]
GEO Series GSE49990. Mus musculus. 16 samples. Type: Expression profiling by array.
Cooperative binding of Oct4, Sox2, and Klf4 with stage-specific transcription factors orchestrates reprogramming [ATAC-seq]
GEO Series GSE90892. Mus musculus. 9 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Aorta- and liver-specific ERalpha-binding patterns and gene regulation by estrogen (ChIP-seq)
GEO Series GSE52351. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Functional characterization of C. elegans Y-box binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes (RIP-Seq)
GEO Series GSE62856. Caenorhabditis elegans. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
Cooperative binding of Oct4, Sox2, and Klf4 with stage-specific transcription factors orchestrates reprogramming [ChIP-seq]
GEO Series GSE90893. Mus musculus. 119 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Protein−DNA binding in the absence of specific base-pair recognition
GEO Series GSE61920. Homo sapiens; synthetic construct. 4 samples. Type: Other.
Quantifying Transcription Factor Specificity with Advanced DNA Universal Microarrays Featuring Long and Modified Binding Sites [48k]
GEO Series GSE299470. Homo sapiens; synthetic construct. 2 samples. Type: Other.
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation
GEO Series GSE130140. Homo sapiens. 92 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other; Methylation profiling by high throughput sequencing.
Opportunistic binding of EcR to open chromatin drives tissue-specific developmental responses [FAIRE-seq]
GEO Series GSE202808. Drosophila melanogaster. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Global Target mRNA Specification and Regulation by RNA-Binding Protein ZFP36/Tristetraprolin/TTP [PAR-CLIP]
GEO Series GSE53184. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.