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334
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334 results for “Cas9”
A Transfection-Free Approach of Gene Editing via a gold-based nanoformulation of the Cas9 protein
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Purification of Recombinant Cas9
<p><strong>SGC Open Notebook Project to Characterize the HMTase NSD3</strong></p> <p><strong>Exp027 Objective:</strong> To purify recombinant Cas9 protein for genome editing experiments. Recombinant Cas9 will be used with synthesized crRNA:tracrRNA to assemble ribonucleoproteins (RNPs) to target the nuclease activity of Cas9 to specific loci within the genome. Using RNPs as opposed to viral delivery of CRISPR gene editing components is advantageous as the expression of Cas9 is transient limiting off-target effects. </p>
Edits of AR in porcine blastocysts after CRISPR Cas9 editing of zygotes
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Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance
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Data from: CRISPR-Cas9 mediated CD133 knockout inhibits colon cancer invasion through reduced epithelial-mesenchymal transition
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NGS Data from: Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage
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Live cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a
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Guide-free Cas9 is detrimental to pig preimplantation embryo development
GEO Series GSE224238. Sus scrofa. 57 samples. Type: Expression profiling by high throughput sequencing.
Cas9-Mediated Knockout of Ndrg2 Enhances the Regenerative Potential of Dendritic Cells for Wound Healing
GEO Series GSE234145. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiling of teloHAEC cells with CRISPR-Cas9-mediated deletion of candidate enhancer regions
GEO Series GSE191253. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Joint single-cell profiling of Cas9 edits and transcriptomes reveals on- and off-target effects on gene expression (RNA-seq)
GEO Series GSE313958. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9-Cas12a platform
GEO Series GSE144281. Homo sapiens; Mus musculus. 14 samples. Type: Other.
StealTHY: enabling CRISPR-Cas9 screens in immunocompetent hosts to expose concealed metastatic regulators [single-end]
GEO Series GSE268044. Mus musculus. 45 samples. Type: Expression profiling by high throughput sequencing.
CRISPR-Cas9 knockout screen informs efficient reduction of the Komagataella phaffii secretome
GEO Series GSE252605. Komagataella phaffii. 12 samples. Type: Expression profiling by high throughput sequencing.
Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking
GEO Series GSE135064. Homo sapiens. 12 samples. Type: Other.
RNA Binding Proteins As Regulators of Oxidative Stress Identified by a Targeted CRISPR-Cas9 Single Guide RNA Library
GEO Series GSE185462. Homo sapiens. 7 samples. Type: Other.
CRISPR-Cas9 editing of the TNPO3 mutation causing Limb-Girdle Muscular Dystrophy type D2 in a muscle cell model
GEO Series GSE198551. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
CHANGE-seq reveals the genome-wide activity of CRISPR-Cas9 [RNA-seq]
GEO Series GSE149362. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
The splicing factor DHX38/PRP16 is required for ovarian clear cell carcinoma tumorigenesis, as revealed by a CRISPR-Cas9 screen
GEO Series GSE188485. Homo sapiens. 4 samples. Type: Other.
Mycobacterium tuberculosis: Cas9 Induced Vs uninduced cultures [Day 4]
GEO Series GSE64133. Mycobacterium tuberculosis H37Rv. 3 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.