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57 results for “Cavitation”
Data from: Toward the development of cavitation technology for gas hydrate prevention
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Walruses produce intense impulse sounds by clap-induced cavitation during breeding displays
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Genetic Diversity, Ecological Niches, and Climate Change Vulnerability of Aspens in the Upper Midwest:Cavitation
Quaking aspen (Populus tremuloides) is the most cosmopolitan tree species in North America and an important native at Cedar Creek and across the Midwest. Aspen stands are quite common through eastern, central, and northern Minnesota, and occur sporadically in cool, wet microclimates across the Great Plains. Currently, these stands are in decline, are poorly reproducing in the wild, and are suffering from a range of stresses. Climate change associated phenomena, drought and altered freeze-thaw cycles, have contributed to massive aspen dieback, especially in the American West. We have received funding from the National Park Service to assess the genetic diversity and hybrid status, age structure and health, ecological niche and historical rate of range contraction, and drought and freezing tolerance physiology of an aspen stand of interest at the Niobrara National Scenic River (NNSR) in northern Nebraska. As part of this project, we are also studying genetic diversity and physiological vulnerability to climate change in quaking and bigtooth (P. grandidentata) aspen populations in Minnesota, Wisconsin, Iowa, South Dakota, and Nebraska. We will use genetic markers to identify genetically unique stands and compare growth and survival of these to populations of the parent species under different drought and freeze-thaw conditions. This study will allow us to better pinpoint the causes of decline in the NNSR aspen stands and aspen stands across the upper Midwest, and potentially provide guidance to managers on the prioritization of particular stands for conservation or in identifying genetic sources for any ex situ conservation or assisted migration.
Data from: Ultrasonic cavitation induces necrosis and impairs growth in three-dimensional models of pancreatic ductal adenocarcinoma
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is a rapidly increasing cause of mortality whose dismal prognosis is mainly due to overwhelming chemoresistance. New therapeutic approaches include physical agents such as ultrasonic cavitation, but clinical applications require further insights in the mechanisms of cytotoxicity. Three dimensional in vitro culture models such as spheroids exploit realistic spatial, biochemical and cellular heterogeneity that may bridge some of the experimental gap between conventional in vitro and in vivo experiments. Purpose: to assess the feasibility and efficiency of inertial cavitation associated or not with chemotherapy, in a spheroid model of PDAC. Methods: we used DT66066 cells ,derived from a genetically-engineered murine PDAC, isolated from KPC-transgenic mice (LSL-KrasG12D/+; LSL-Trp53R172H/+; Pdx-1- Cre). Spheroids were obtained by either a standard centrifugation-based method, or by using a magnetic nano-shuttle method allowing the formation of spheroids within 24 hours and facilitating their handling. The spheroids were exposed to ultrasonic inertial cavitation in a specially designed setup. Four conditions were studied: control, gemcitabine alone , US cavitation alone , US cavitation + gemcitabine. Five US inertial cavitation indexes, corresponding to increased US intensities, were evaluated . The effectiveness of treatment was assessed after 24 hours with the following criteria: spheroid size (growth), ratio of phase S cells (proliferation), proportion of cells in apoptosis or necrosis (cellular mortality). These parameters were assessed by quantitative immunofluorescence techniques. Results: The 3D culture model presented excellent reproducibility. Eight or nine spheroids were analyzed for each condition. Cavitation induced a significant decrease in the size of spheroids , an effect significantly correlated to an increasing cavitation index (p < 0.0001). The treatment induced cell death whose predominant mechanism was necrosis (p < 0.0001). There was a tendency to a synergistic effect of US cavitation and gemcitabine at 5μM concentration, however significant in only one of the cavitation indexes used (p = 0. 013). Conclusion: Ultrasonic inertial cavitation induced a significant reduction of tumor growth in a spheroid model of PDAC., with necrosis rather than apoptosis as a Cell dominant mechanism of cell death. More investigations are needed to understand the potential role of inertial cavitation in overcoming chemoresistance.
A First in Human Study to Compare Feasibility of Inertial Cavitation Irrigation to SNI in Root Canal Treatment.
ClinicalTrials.gov study NCT05374434. IPD Sharing: NO. Countries: 1. Publications: 0.
Cavitation Ultrasound in Treatment of Patients With PCOS
ClinicalTrials.gov study NCT01622257. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Diagnostic Performance and Children's Acceptance of Near-Infrared Light Transillumination and Bitewing Radiographs for Detecting Proximal Cavitation in Primary Molars of Patients Aged 4 to 10 Years
ClinicalTrials.gov study NCT07041164. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions
ClinicalTrials.gov study NCT03649659. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Ultrasonic cavitation induces necrosis and impairs growth in three-dimensional models of pancreatic ductal adenocarcinoma
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FFPE-samples from cavitational ultrasonic surgical aspirates are suitable for RNA profiling of gliomas
GEO Series GSE166696. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Size-Modulated Mesoderm-Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids
GEO Series GSE293554. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis
GEO Series GSE68206. Oryctolagus cuniculus. 36 samples. Type: Expression profiling by high throughput sequencing.
Effectiveness of Diathermy-Radiofrecuency Compared With Cavitation in Cellulitis Treatment
ClinicalTrials.gov study NCT03474523. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Ultrasonic Cavitation on Abdominal Obesity in Adolescent Females
ClinicalTrials.gov study NCT04930068. IPD Sharing: NO. Countries: 1. Publications: 0.
Chemotherapy and Radiation Therapy With or Without Panitumumab in Treating Patients Who Have Undergone Surgery for Advanced Hypopharyngeal Cancer, Oropharyngeal Cancer, Laryngeal Cancer, or Oral Cavit
ClinicalTrials.gov study NCT01142414. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Effect of Self-Assembling Peptides on the Progression of Non-Cavitated Proximal Caries
ClinicalTrials.gov study NCT04776785. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Ultrasound Cavitation Versus Radiofrequency on Abdominal Fat
ClinicalTrials.gov study NCT04452552. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion
ClinicalTrials.gov study NCT05202665. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluation of Conservative Management of Teeth With Deep Cavitated Carious Lesions
ClinicalTrials.gov study NCT06171776. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Ultrasound Cavitation on Insulin Resistance in Patients with Central Obesity in Female
ClinicalTrials.gov study NCT06729203. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.