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270
datasets available to search
ShareScore release 0.9.0
Dataset results
270 results for “Cerebellum”
Elemental bioimaging and transcriptomics – no evidence of altered gene expression after single injection of Gadolinium-based contrast agents in mice cerebellum
<p>single read RNA data for GBCA study</p>
P0-mip3_cerebellum_ssSEM_dataset
<p>P0-mip3_cerebellum_ssSEM_dataset</p> <p>Produced in collaboration between the Zurzolo lab at Institut Pasteur and the Lichtman lab at Harvard University</p>
P7 mouse cerebellum ssSEM molecular layer
<p>This dataset is meant for training of CellWalker automatic segmentation notebook that uses a UNET convolutional neural network.</p> <p>The code can be found on GitHub- https://github.com/utraf-pasteur-institute/CellWalker-notebooks</p>
Transcranial Electrical Stimulation Targeting the Cerebellum for the Treatment of Refractory Temporal Lobe Epilepsy
ClinicalTrials.gov study NCT06558890. IPD Sharing: NO. Countries: 1. Publications: 15.
Cerebellum and Cortical Plasticity: the Case of Dystonia
ClinicalTrials.gov study NCT01272154. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Modulation of the Activity of the Cerebellum in Autism (MACA)
ClinicalTrials.gov study NCT05781412. IPD Sharing: UNDECIDED. Countries: 1. Publications: 26.
Integrated Functional Evaluation of the Cerebellum
ClinicalTrials.gov study NCT04288128. IPD Sharing: Not stated. Countries: 1. Publications: 2.
The Role of Cerebellum in Speech
ClinicalTrials.gov study NCT03972202. IPD Sharing: NO. Countries: 1. Publications: 17.
cTBS Targeting Cerebellum for Drug-refractory Epilepsy
ClinicalTrials.gov study NCT05042726. IPD Sharing: NO. Countries: 1. Publications: 10.
Interactions Between Striatum and Cerebellum in ADCY5 and PRRT2 Dystonias
ClinicalTrials.gov study NCT03481491. IPD Sharing: NO. Countries: 1. Publications: 2.
Abnormal Movements, Cerebellum and Sensorimotor : Oculomotor Study
ClinicalTrials.gov study NCT01495897. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Cerebellum or Supplementary Motor Area Functional Inactivation on Gait and Balance Control
ClinicalTrials.gov study NCT02976298. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Quantitative anatomy of the cerebellum on chickens and junglefowl
Open the record for dataset details and reuse information.
Data from: Encoding of locomotion kinematics in the mouse cerebellum
Open the record for dataset details and reuse information.
Brain cerebellum
Drawing uploaded to scidraw.io on: 30 March 2020
Slideseq cerebellum and scRNAseq cerebellum
<p>Contains the slideseq cerebellum dataset (Science paper), and the single-cell RNAseq L1 cerebellum dataset (from mouse-brain.org).</p> <p>For use with Giotto, and Giotto dataset tutorials.</p>
TMS over the posterior cerebellum modulates motor cortical excitability in response to facial emotional expressions
<p>Evidence suggests that the posterior cerebellum is involved in emotional processing. Specific mechanisms by which the cerebellum contributes to the perception of and reaction to the emotional state of others are not well-known. It is likely that perceived emotions trigger anticipatory/preparatory motor changes. However, the extent to which the cerebellum modulates the activity of the motor cortex to contribute to emotional processing has not been directly investigated. In this study, we assessed whether the activity of the posterior cerebellum influences the modulation of motor cortical excitability in response to emotional stimuli. To this end, we transiently disrupted the neural activity of the left posterior cerebellum using 1 Hz repetitive transcranial magnetic stimulation (rTMS) and examined its effect on motor cortical excitability witnessed during emotional face processing (in comparison to the effects of sham rTMS). Motor excitability was measured as TMS-based motor evoked potentials (MEPs) recorded from bilateral first dorsal interosseous (FDI) muscles during the viewing of negative emotional (i.e. fearful) and neutral facial expressions. In line with previous evidence, we found that MEP amplitude was increased during the viewing of fearful compared to neutral faces. Critically, when left posterior cerebellar activity was transiently inhibited with 1 Hz rTMS, we observed a reduction in amplitude of MEPs recorded from the contralateral (right) motor cortex during the viewing of emotional (but not neutral) faces. In turn, inhibition of the left posterior cerebellum did not affect the amplitude of MEPs recorded from the ipsilateral motor cortex. Our findings suggest that the posterolateral (left) cerebellum modulates motor cortical response to negative emotional stimuli and may serve as an interface between limbic, cognitive, and motor systems.</p>
The left posterior cerebellum is involved in orienting attention along the mental number line: An online-TMS study
<p>Although converging evidence suggests that the posterior cerebellum is involved in visuospatial functions and in the orienting of attention, a clear topography of cerebellar regions causally involved in the control of spatial attention is still missing. In this study, we aimed to shed light on this issue by using online neuronavigated transcranial magnetic stimulation (TMS) to temporarily interfere with posterior medial (Vermis lobule VII) and left lateral (Crus I/II) cerebellar activity during a task measuring visuospatial (landmark task, Experiment 1 and 2) and representational (number bisection task, Experiment 2) asymmetries in the orienting of attention. At baseline, participants showed attentional biases consistent with the literature, that is a leftward and upward bias with horizontal and vertical lines, respectively, and a leftward bias in number bisection. Critically, TMS over the left cerebellar hemisphere significantly counteracted pseudoneglect in the number bisection task, whilst not affecting attentional biases in the landmark task. In turn, TMS over the posterior vermis did not affect performance in either task. Taken together, our findings suggest that the left posterior cerebellar hemisphere (but not the posterior vermis) is a critical node of an extended brain network subtending the control of spatial attention, at least when attention needs to be allocated to an internal representational space and a certain degree of mental manipulation is required (as in the number bisection task).</p>
Data from: A trade-off between reproductive investment and maternal cerebellum size in a precocial bird
Natural selection favours increased investment in reproduction, yet considerable variation in parental investment is observed in natural populations. Life-history theory predicts that this variation is maintained by a trade-off between the benefits of increased reproductive investment and its associated costs for the parents. The nature of these costs of reproduction, however, remains poorly understood. The brain is an energetically highly expensive organ and increased reproductive investment may, therefore, negatively affect brain maintenance. Using artificial selection lines for high and low prenatal maternal investment in a precocial bird, the Japanese quail (Coturnix japonica), we provide experimental evidence for this hypothesis by showing that increased prenatal provisioning negatively affects the size of a particular brain region of the mother, the cerebellum. Our finding suggests that cognitive demands may constrain the evolution of parental investment, and vice versa, contributing to the maintenance of variation in reproductive behaviour in animal populations.
Data from: Functional role of the cerebellum in Parkinson's disease: a PET study
<p><span><b>Objectives:</b> To test for cerebellar involvement in motor and nonmotor impairments in Parkinson's disease (PD), and to determine patterns of metabolic correlations with supratentorial brain structures, we correlated clinical motor, cognitive and psychiatric scales with cerebellar metabolism.</span></p> <p><span><b>Methods: </b>We included 90 patients with PD. Motor, cognitive and psychiatric domains were assessed, and resting-state <sup>18</sup>FDG-PET metabolic imaging was performed. The motor, cognitive and psychiatric scores were entered separately in a principal component analysis. We looked for correlations between these three principal components and cerebellar metabolism. Furthermore, we extracted the mean glucose metabolism value for each significant cerebellar cluster and looked for patterns of cerebrum‑cerebellum metabolic correlations.</span></p> <p><span><b>Results:</b> Severity of impairment was correlated with increased metabolism in the anterior lobes and vermis (motor domain), and the right Crus I, Crus II, and declive (cognitive domain), and the right Crus I and Crus II (psychiatric domain). There were no results surviving multiple testing corrections regarding the psychiatric domain. Moreover, we found distributed and overlapping ‑ but not identical‑ patterns of metabolic correlations for motor and cognitive domains. Specific supratentorial structures (cortical structures, basal ganglia, and thalamus) were strongly correlated with each of the cerebellar clusters. </span></p> <p><span><b>Conclusions:</b> These results confirm the role of the cerebellum in nonmotor domains of Parkinson's disease, with differential but overlapping patterns of metabolic correlations suggesting the involvement of cerebello‑thalamo-striatal‑cortical loops.</span></p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.