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Dataset results
278 results for “Dengue virus”
ADVP005; Dengue CVD 12000 - Dengue-1-Virus Live Virus Human Challenge (DENV-1-LVHC)
ClinicalTrials.gov study NCT04786457. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Safety and Immunogenicity Study of a Dengue Virus DNA Vaccine
ClinicalTrials.gov study NCT00290147. IPD Sharing: NO. Countries: 1. Publications: 2.
Sylvatic Transmission of Zika, Dengue, and Chikungunya Viruses in Thailand and Cambodia
ClinicalTrials.gov study NCT04434846. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Mechanical transmission of Dengue Virus by Aedes aegypti may influence disease transmission dynamics during outbreaks data
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Underlying data for 'Rapid molecular assays for the detection of the four dengue viruses in infected mosquitoes'
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Selection pressure analysis of dengue virus complete genome and E gene nucleotide sequences from Pakistan
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RNA sequences for Aedes species, Dengue, and Chikungunya viruses
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FIGURE F in Pictorial keys for the identification of mosquitoes (Diptera: Culicidae) associated with Dengue Virus Transmission
FIGURE F. Dorsal view of mosquito larva (segments VIII and X, lateral view) Aedes (Stegomyia) albopictus.
Dataset: Prevalence of Antibodies Against Dengue Virus in Buenos Aires
<p>This anonymized dataset was collected as part of the study titled "Prevalence of Antibodies Against Dengue Virus in Buenos Aires: Results of a Probabilistic Population Survey." It contains data on the prevalence of antibodies against dengue virus in the general population of Buenos Aires, obtained through a representative probabilistic survey. The dataset includes basic demographic variables, serological results (IgG and IgM), and other related characteristics. All personal identifiers have been removed to ensure participant privacy. This dataset aims to support analysis and reproducibility of the published findings</p>
Supplemental information for- In-silico evaluation of potential inhibitors against all serotypes of Dengue Virus Envelope Glycoprotein
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FIGURE 2 in The Asian tiger mosquito, Aedes (Stegomyia) albopictus (Skuse), a vector of dengue, chikungunya and zika viruses, reaches Portugal (Diptera: Culicidae)
FIGURE 2. Portuguese Aedes albopictus females seeking human blood. Note characteristic scutal white stripe, distinct silvery-white scales on the maxillary palpi and tarsi, as well as narrow scales over the wing root and silvery-white basolateral abdominal tergal markings.
FIGURE 1 in The Asian tiger mosquito, Aedes (Stegomyia) albopictus (Skuse), a vector of dengue, chikungunya and zika viruses, reaches Portugal (Diptera: Culicidae)
FIGURE 1. Distribution of Aedes albopictus in the Iberian Península. In green, distribution in Spain according to Collantes et al. (2016). In red, highlighted by arrow, new occurrence in Portugal.
FIGURE 3 in The Asian tiger mosquito, Aedes (Stegomyia) albopictus (Skuse), a vector of dengue, chikungunya and zika viruses, reaches Portugal (Diptera: Culicidae)
FIGURE 3. Biting activity of Ae. albopictus assessed by human-bait catches. Specimens arriving to bite were captured every 15 minutes to avoid recapture. The x axis is a timeline of 15-minute intervals; the y axis is an average of the three days of sampling.
Assessment of a multiplex PCR and Nanopore-based method for portable dengue virus sequencing in Indonesia
<p>Multiplex primer sets for amplification of the complete coding region of Indonesian dengue virus.</p>
Data from: Monocyte recruitment to the dermis and differentiation to dendritic cells increases the targets for Dengue virus replication
Dengue virus (DENV) causes the most prevalent arthropod-borne viral disease in humans. Although Aedes mosquitoes transmit DENV when probing for blood in the skin, no information exists on DENV infection and immune response in the dermis, where the blood vessels are found. DENV suppresses the interferon response, replicates, and causes disease in humans but not wild-type mice. Here, we used mice lacking the interferon-α/β receptor (Ifnar–/–), which had normal cell populations in the skin and were susceptible to intradermal DENV infection, to investigate the dynamics of early DENV infection of immune cells in the skin. CD103+ classical dendritic cells (cDCs), Ly6C– CD11b+ cDCs, and macrophages in the steady-state dermis were initial targets of DENV infection 12-24 hours post-inoculation but then decreased in frequency. We demonstrated recruitment of adoptively-transferred Ly6Chigh monocytes from wild-type and Ifnar–/– origin to the DENV-infected dermis and differentiation to Ly6C+ CD11b+ monocyte-derived DCs (moDCs), which became DENV-infected after 48 hours, and were then the major targets for virus replication. Ly6Chigh monocytes that entered the DENV-infected dermis expressed chemokine receptor CCR2, likely mediating recruitment. Further, we show that ~100-fold more hematopoietic cells in the dermis were DENV-infected compared to Langerhans cells in the epidermis. Overall, these results identify the dermis as the main site of early DENV replication and show that DENV infection in the skin occurs in two waves: initial infection of resident cDCs and macrophages, followed by infection of monocytes and moDCs that are recruited to the dermis. Our study reveals a novel viral strategy of exploiting monocyte recruitment to increase the number of targets for infection at the site of invasion in the skin and highlights the skin as a potential site for therapeutic action or intradermal vaccination.
Fig. 8 in Recent advances in natural products as potential inhibitors of dengue virus with a special emphasis on NS2b/NS3 protease
Fig. 8. (a) The general structure of a flavonoid. (b) Chemical structures of the flavonoids – quercetin (14), kaempferol-3-O-rutinoside (16), rutin (17), hyperoside (18), the chromanone derivative (20), myricetin (23), apigenin (24), and luteolin (25), (c) pongamol (15), (d) epicatechin (19), catechin (27), EGCG (29), hesperetin (32), and hesperidin (33), (e) amentoflavone (21), (f) curcumin (22), (g) delphinidin (26), and (h) rotenone (30).
Fig. 1 in Recent advances in natural products as potential inhibitors of dengue virus with a special emphasis on NS2b/NS3 protease
Fig. 1. An illustration of dengue virus structure showing the lipid bilayer, the structural proteins, and the positive RNA strand.
Fig. 7 in Recent advances in natural products as potential inhibitors of dengue virus with a special emphasis on NS2b/NS3 protease
Fig. 7. Chemical structures of ganodermanontriol (10), lucidumol A (11), ganoderic acid C2 (12), and ganosporeric acid A (13). Wherein, () indicates a wedged bond; (- - -) indicates a hashed bond.
Fig. 9 in Recent advances in natural products as potential inhibitors of dengue virus with a special emphasis on NS2b/NS3 protease
Fig. 9. Chemical structures of the phenolic compounds (a) gallic acid (31), methyl orsellinate (34), resveratrol (35), gingerol (36), anacardic acid (37), and cardol triene (38), (b) tatanan A (39).
Fig. 2 in Recent advances in natural products as potential inhibitors of dengue virus with a special emphasis on NS2b/NS3 protease
Fig. 2. Flavivirus life cycle since its binding to the host's mannose-binding receptor (MR) and/or the dendritic cell-specific intercellular adhesion molecule-3- grabbing non-integrin (DC-SIGN) receptor, and the cleavage of the translated polyprotein into the structural (C; capsid, M; membrane, and E; envelope) and the non-structural proteins (NS1, NS2a, NS2b, NS3, NS4a, NS4b, and NS5).
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.