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6,699 results for “Depression”
Understanding in vivo Models of Depression: A Systematic Review - Records of Full Search
<p>This Zenodo record outlines the full list of journal articles retrieved from the search string as well as a a subset of articles that have been screened by two independent human reviews and reconciled by a third independent screener. </p> <p> </p> <p>We carried out a search of 2 online databases for studies reporting animal models of depression. This search, carried out in May 2016, identified 70,365 unique publications (File: Depression-Dataset-SLIM-AllRecords.txt )</p> <p> </p> <p>Two independent investigators have, to date, screened 5749 of these publications for inclusion or exclusion and these publications form the dataset for this study (File: Updated-training-data.txt ). </p> <p>Several text-mining approaches will be developed for this depression literature search using the results from manual screening to train the machine, where machine-learning software set rules to automatically define each publication as included or excluded without the need for human screening. In this project, we seek to identify the best performing machine learning algorithm for this depression literature search. Performance is measured on sensitivity, specificity, and precision. </p> <p> </p> <p>Column Names in Datasets: </p> <p>Depression-Dataset-SLIM-AllRecords.txt - ID, Author, Year, Title, Journal, Volume, Issue, Pages, Abstract, URL, SetNumber</p> <p>Depression-Dataset-SLIM-DevelopmentTrainingSet.txt - ID, Author, Year, Title, Journal, Volume, Issue, Pages, Abstract, URL, Incl(1)/Excl(0)</p> <p>Updated-training-data.txt - ID, Author, Year, Title, Journal, Volume, Issue, Pages, Abstract, URL, Incl(1)/Excl(0)</p> <p> </p>
Data and R script for Neville, Andrews, Nettle and Bateson, 'Dissociating the effects of alternative early-life feeding schedules on the development of adult depression-like phenotypes'
<p>The R script and raw data files for the paper 'Dissociating the effects of alternative early-life feeding schedules on the development of adult depression-like phenotypes', by Vikki Neville, Clare Andrews, Daniel Nettle and Melissa Bateson.</p>
The prevalence and correlates of depression and anxiety symptoms among older adults in Shenzhen, China
<p><strong>Objectives: </strong>To investigate the prevalence of depression and anxiety symptoms among older adults in an urban district in China, as well as their associated factors.</p> <p><strong>Participants:</strong> A total of 5,372 community-dwelling older adults aged 65 years or older were initially recruited. Ultimately, 5,331 participants met the inclusion criteria and were included in this study.</p> <p><strong>Methods:</strong> Participants completed a sociodemographic questionnaire, along with assessments including the Patient Health Questionnaire-9, Generalized Anxiety Scale-7, UCLA Loneliness Simplification Scale, Insomnia Severity Index Scale, Community Dementia Brief Screening Scale, and the 8-item Dementia Screening Questionnaire. Statistical analyses included the Shapiro‒Wilk test, independent t-test, Wilcoxon rank test, c<sup>2</sup> test, and univariate and multivariate linear regression analysis.</p> <p><strong>Results:</strong> The prevalence of depression and anxiety symptoms among older adults in Shenzhen communities was 10.4% and 11.3%, respectively. In multivariate analysis, age (B=-0.01, <em>P</em><0.05), relatively poor health status in the past year (B=1.00, <em>P</em><0.01), poor health status in the past year (B=2.40, <em>P</em><0.01), ISI score (B=0.21, <em>P</em><0.01), AD8 score (B=0.22, <em>P</em><0.01), ULS score (B=0.24, <em>P</em><0.01) were significantly associated with the severity of depression symptom, Compared to their respective reference categories, relatively poor health status in the past year (B=0.50, <em>P</em><0.01), poor health status in the past year (B=1.32, <em>P</em><0.01), ISI score (B=0.23, <em>P</em><0.01), sleep duration (B=0.05, <em>P</em><0.01), AD8 score (B=0.21, <em>P</em><0.01), CSID score (B=0.13, <em>P</em><0.01), ULS score (B=0.22, <em>P</em><0.01) were significantly associated with the severity of anxiety symptom.</p> <p><strong>Conclusions: </strong>We observed a high prevalence of depression and anxiety symptoms among older adults in this study. The existing welfare system and infrastructure should remain and targeted mental health programs addressing the identified risk factors should be proposed.</p>
Iron-rich grain-decorated Depressions on Surfaces of Lunar Impact Glasses
<p>The dataset includes the semi-quantitative values and EDS spectra of constitutions of iron-rich grain-decorated depressions on surfaces of Chang'E-5 impact glass particles. Semi-quantitative values were classified by ultra-thin sections, and EDS spectra were marked by sampling sites.</p>
Whole-body physiology model to simulate respiratory depression of fentanyl and associated naloxone reversal
<p>Opioid use in the United States and abroad is an endemic part of society with yearly increases in overdose rates and deaths. As rates of overdose incidence increase, the use of the safe and effective reversal agent, naloxone, in the form of a nasal rescue spray is being fielded and used by emergency medical technicians (EMTs) at a greater and greater rate. Despite advances in the deployment of these rescue products, deaths are continuing to increase. There is evidence that repeated dosing of a naloxone nasal spray (such as Narcan) is becoming more common due to the amount and type of opiate being administered. Despite the benefits of naloxone related to opioid reversals, we lack repeated dosing guidelines as a function of opiates and the amount the patient has taken. Goal-directed rescue dosing, where respiratory markers such as oxygen saturation or end-tidal carbon dioxide, are being used as an indication of the patient's recovery. These rescue methods require time, training, and understanding by the EMT to administer with most patients receiving naloxone doses with no follow-up or additional monitoring. To measure repeat dosing guidelines, we construct a whole-body model of the pharmacokinetics and dynamics of an opiate, fentanyl on respiratory depression. We then construct a model of nasal deposition and administration of naloxone to investigate repeat dosing requirements for large overdose scenarios. We demonstrate that naloxone is highly effective at reversing the respiratory symptoms of the patient and recommend dosing requirements as a function of the fentanyl amount administered. By designing the model to include circulation and respiration we investigate physiological markers that may be used in goal-directed therapy rescue treatments.</p>
Dataset accompanying the journal article: Bouldering psychotherapy is not inferior to cognitive behavioural therapy in the group treatment of depression: A randomized controlled trial
<p>SPSS-Dataset containing the (not-imputed) raw data for the non-inferiority trial on BPT vs. CBT. All personal data removed. Only data of participants of the CBT or BPT group included.</p>
Application of Mass Multivariate Analysis on Neuroimaging Data Sets for Precision Diagnosis of Depression: Data and code
<p><strong>In the archive are the datasets and code used to create the results in article "Application of Mass Multivariate Analysis on Neuroimaging Data Sets fo Precision Diagnosis of Depression". The methods is based on the Multivariate Linear toolbox mad F. Kherif’s lab and available on GitHub. <a href="https://github.com/LREN-CHUV/MLM">https://github.com/LREN-CHUV/MLM</a>. </strong></p> <p><strong>A total of 44 patients with a current psychotic (n=19) or depressive (n=25) episode were analyzed by MLM (details can be found in the article itself) utilizing resting sate fMRI, tasks fMRI, and anatomical T1w images. </strong></p> <p><strong>The data results are provided in MATLAB format, in a matrix called MLM.mat. The matrix includes the canonical variables for each of the three imaging modalities, chi-square statistics, and p-values for each brain region. Additionally, we provided a function MLM_plot_fun that allows mapping the statistics results to a canonical three-dimensional brain as per the article. </strong></p>
Beyond depression and anxiety; a systematic review about the role of corticotropin-releasing hormone antagonists in diseases of the pelvic and abdominal organs-Worksheets
<p>This file has several worksheets corresponding to the data used for the review with the same table as indicated in the file</p>
Data supporting the manuscript "Sexually divergent development of depression-related brain networks during healthy human adolescence"
<p>This data supports the manuscript "Sexually divergent development of depression-related brain networks during healthy human adolescence" by Dorfschmidt et al. Part of these <a href="https://doi.org/10.6084/m9.figshare.11551602">data</a> were initially released by Váša et al. (2020) as part of their <a href="https://doi.org/10.1073/pnas.1906144117">manuscript</a>. Please cite them when using these data. </p> <p> </p>
HGDM - the Hysteretic and Gatekeeping Depressions Model
<p>The Hysteretic and Gatekeeping Depressions Model simulates the variable contributing fractions of Canadian Prairie basins.<br> These files will include the model code as well as data files used to develop and test the model.</p> <p> </p>
Text-fig. 8. Carpolithes (a–t). a–e: Carpolithes sp. 1. USNM PAL 772366. Scale bar = 1 cm. a: Lateral view of endocarp, note two longitudinal ridges. b: Lateral view of endocarp rotated 90° from (a), note single lateral ridge in center, a, b reflected light, palladium coated. c: Lateral view, Micro-CT scan surface rendering. d: View of rounded end of the endocarp, reflected light, palladium coated. e: View of the opposite (pointed) end of the endocarp, note split; reflected light, palladium coated. f–j: Carpolithes sp. 2. USNM PAL 772367. Scale bar = 5 mm. f: Lateral view, base down; note raphe-like structure (arrow), reflected light, palladium coated. g: Lateral view, the raphe-like structure extending vertically from the base. h: Lateral view, rotated 90° from (g). i: Lateral view, the opposite face to that in (h). j: Basal view, raphe-like structure running from the center to the right of the image. g–j: CT scan surface renderings. k–o: Carpolithes sp. 3 USNM PAL 772368. Scale bar = 5 mm. k: Ventral view of the specimen, note flared apical extension, reflected light, uncoated. l: Dorsal view illustrating the flared apical extension, rotated 180o from (k). m: Lateral view rotated 90° from that in (l). n: Apical view, the apical extension with central pore (arrow) and a clear lineation running down the side to the top of the image. o: Basal view. l–o: Micro-CT scan surface renderings. p–t: Carpolithes sp. 4. USNM PAL 772369. Scale bar = 3 mm. p: Basal view illustrating the concentric rings of radiating possible cells surrounding a central depression. q: Lateral view, base down, note possible cellular pattern. r: Lateral view, rotated 180° from (q), base down; p–r: reflected light, palladium coated. s, t: Basal and lateral views, micro-CT scan surface renderings. in The Early Middle Eocene Wagon Bed Carpoflora Of Central Wyoming, U.S.A.
Text-fig. 8. Carpolithes (a–t). a–e: Carpolithes sp. 1. USNM PAL 772366. Scale bar = 1 cm. a: Lateral view of endocarp, note two longitudinal ridges. b: Lateral view of endocarp rotated 90° from (a), note single lateral ridge in center, a, b reflected light, palladium coated. c: Lateral view, Micro-CT scan surface rendering. d: View of rounded end of the endocarp, reflected light, palladium coated. e: View of the opposite (pointed) end of the endocarp, note split; reflected light, palladium coated. f–j: Carpolithes sp. 2. USNM PAL 772367. Scale bar = 5 mm. f: Lateral view, base down; note raphe-like structure (arrow), reflected light, palladium coated. g: Lateral view, the raphe-like structure extending vertically from the base. h: Lateral view, rotated 90° from (g). i: Lateral view, the opposite face to that in (h). j: Basal view, raphe-like structure running from the center to the right of the image. g–j: CT scan surface renderings. k–o: Carpolithes sp. 3 USNM PAL 772368. Scale bar = 5 mm. k: Ventral view of the specimen, note flared apical extension, reflected light, uncoated. l: Dorsal view illustrating the flared apical extension, rotated 180o from (k). m: Lateral view rotated 90° from that in (l). n: Apical view, the apical extension with central pore (arrow) and a clear lineation running down the side to the top of the image. o: Basal view. l–o: Micro-CT scan surface renderings. p–t: Carpolithes sp. 4. USNM PAL 772369. Scale bar = 3 mm. p: Basal view illustrating the concentric rings of radiating possible cells surrounding a central depression. q: Lateral view, base down, note possible cellular pattern. r: Lateral view, rotated 180° from (q), base down; p–r: reflected light, palladium coated. s, t: Basal and lateral views, micro-CT scan surface renderings.
Text-fig. 9. Carpolithes (a–r). a–d: Carpolithes sp. 5. USNM PAL 772370. Scale bar = 5 mm, reflected light, palladium coated. a: Lateral view of seed, apex up, possible raphe descending from apex toward viewer. b: Lateral view of seed, apex up, possible raphe on right. c: Lateral view, opposite side, apex up, possible raphe on left. d: Apical view, note central pit with raphe descending towards bottom margin. e–h: Carpolithes sp. 6. USNM PAL 772371. Scale bar = 5 mm. e: Basal view illustrating depression and keel in plane of bisymmetry, reflected light, palladium coated. f–h: Micro-CT scan surface rendering. f: Lateral view showing relatively smooth rounded surface. g: Specimen rotated 180° from (f), surface partially eroded. h: Longitudinal view, showing median keel. i–m: Carpolithes sp. 7 USNM PAL 772372. Scale bar = 5 mm. i: View of intact face of globose fruit, possible apical constriction at top. j: Lateral view, intact surface to right, possible apical constriction at top, both micro-CT scan surface renderings. k: Apical view. l: Face view illustrating the mineral filling and the fine, radiating structure of the fruit wall on the left and right margins, both reflected light, palladium coated. m: Closeup of the cellular layer on the left of (l), micro-CT scan surface rendering. n–p: Carpolithes sp. 8. USNM PAL 772373. Scale bar = 3 mm, reflected light, palladium coated. n: Lateral view of pyrene-like structure, one ridge running vertically in the center of view, the other two forming the left and right margins. o: Lateral view of pyrene-like structure, ridge in (n) on the left. p: End-on view illustrating one convex, one concave, and one relatively flat to very slightly concave face. q, r: Carpolithes sp. 9 USNM PAL 772374. Scale bar = 5 mm, reflected light, palladium coated. q: Exterior of the smooth broken half-sphere. r: Interior of the broken half-sphere. in The Early Middle Eocene Wagon Bed Carpoflora Of Central Wyoming, U.S.A.
Text-fig. 9. Carpolithes (a–r). a–d: Carpolithes sp. 5. USNM PAL 772370. Scale bar = 5 mm, reflected light, palladium coated. a: Lateral view of seed, apex up, possible raphe descending from apex toward viewer. b: Lateral view of seed, apex up, possible raphe on right. c: Lateral view, opposite side, apex up, possible raphe on left. d: Apical view, note central pit with raphe descending towards bottom margin. e–h: Carpolithes sp. 6. USNM PAL 772371. Scale bar = 5 mm. e: Basal view illustrating depression and keel in plane of bisymmetry, reflected light, palladium coated. f–h: Micro-CT scan surface rendering. f: Lateral view showing relatively smooth rounded surface. g: Specimen rotated 180° from (f), surface partially eroded. h: Longitudinal view, showing median keel. i–m: Carpolithes sp. 7 USNM PAL 772372. Scale bar = 5 mm. i: View of intact face of globose fruit, possible apical constriction at top. j: Lateral view, intact surface to right, possible apical constriction at top, both micro-CT scan surface renderings. k: Apical view. l: Face view illustrating the mineral filling and the fine, radiating structure of the fruit wall on the left and right margins, both reflected light, palladium coated. m: Closeup of the cellular layer on the left of (l), micro-CT scan surface rendering. n–p: Carpolithes sp. 8. USNM PAL 772373. Scale bar = 3 mm, reflected light, palladium coated. n: Lateral view of pyrene-like structure, one ridge running vertically in the center of view, the other two forming the left and right margins. o: Lateral view of pyrene-like structure, ridge in (n) on the left. p: End-on view illustrating one convex, one concave, and one relatively flat to very slightly concave face. q, r: Carpolithes sp. 9 USNM PAL 772374. Scale bar = 5 mm, reflected light, palladium coated. q: Exterior of the smooth broken half-sphere. r: Interior of the broken half-sphere.
Dataset from: "Assessment of depression, anxiety, and psychological symptoms in parents of pediatric palliative care patients: A single-center case-control study"
<p>The dataset comprises raw data from a case-control study that compared levels of depression, anxiety, and general psychological symptoms between parents of pediatric palliative care (PPC) patients and parents of healthy controls.</p> <p>Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Symptom Checklist-90 Revised (SCL-90-R) were employed to provide a comprehensive and nuanced understanding of the mental health challenges faced by parents.</p> <p>The designation "case" in the first column (A) represents the parents of PPC patients, while the designation "control" represents the control group. The columns labeled B to S present demographic characteristics data, while columns T to AR present inventory scores. Columns BB to GC, in turn, present the responses to the inventory items.</p> <p> </p> <p> </p>
Fig. 5 in Upper Burdigalian-Middle Sarmatian Calcareous Nannofossils From Totea-Văleni Area (Getic Depression, Romania)
Fig. 5 Upper Badenian-Bessarabian calcareous nannofossils: a Braarudosphaera bigelowii (Gran & Braarud) Deflandre (TO-1 borehole); b Calcidiscus macintyrei (Bukry & Bramlette) Loeblich & Tappan (TO-1 borehole); c Catinaster coalitus Martini & Bramlette (VA-1 borehole); d, e Discoaster exilis Martini & Bramlette (TO-1 borehole); f Discoaster musicus Stradner (TO-1 borehole); g Helicosphaera carteri (Wallich) Kamptner (TO-1 borehole); h Helicosphaera walberdorfensis Mueller (TO-1 borehole); i Reticulofenestra minuta Roth (TO-1 borehole); j Reticulofenestra perplexa (Burns) Wise (VA-1 borehole); k, l Sphenolithus abies Deflandre (VA-1 borehole); m Syracosphaera pulchra Lohmann (TO-1 borehole); n Noelaerhabdus bozinovicae tegulatus Bona & Gal (VA-1 borehole); o, p Isolithus semenenko Luľjeva (o – VA-1 borehole, p – RA-1 borehole).
Fig. 3 in Upper Burdigalian-Middle Sarmatian Calcareous Nannofossils From Totea-Văleni Area (Getic Depression, Romania)
Fig. 3 Upper Burdigalian calcareous nannofossils: a, b Calcidiscus leptoporus (Murray & Bramlette) Loeblich & Tappan (VA-1 borehole; a – N+ with ʎ compensator, b – NII with ʎ compensator); c Calcidiscus macintyrei (Bukry & Bramlette) Loeblich & Tappan (CO-1 borehole, N+); d Coccolithus miopelagicus Bukry (TO-2 borehole, NII); e Cyclicargolithus floridanus (Roth & Hay) Bukry (TO-2 borehole, NII); f, g Helicosphaera ampliaperta Bramlette & Wilcoxon (TO-1 borehole, f – N+, 7 – gNII); h Helicosphaera intermedia Martini (CO-1 borehole, N+); i, j Pontosphaera multipora (Kamptner) Roth (TO-3 borehole, i – N+, j – N+ with ʎ compensator); k, l Sphenolithusheteromorphus Deflandre (TO-3 borehole, k – N+,0o, l – N+, 45o).
Fig. 4 in Upper Burdigalian-Middle Sarmatian Calcareous Nannofossils From Totea-Văleni Area (Getic Depression, Romania)
Fig. 4 Lower to middle Badenian calcareous nannofossils: a Discoaster variabilis Martini & Bramlette (TO-2 borehole, NII); b Helicosphaera wallichii (Lohmann) Boudreaux & Hay (TO-2 borehole, N+); c, d Sphenolithus heteromorphus Deflandre (RA-1 borehole, c – N+, 0o, d – N+, 45o); e, f Pontosphaera discopora Schiller (RA-1 borehole, e – N+, f – NII), g Reticulofenestra haqii Backman (CO-1 borehole, N+); h Reticulofenestra pseudoumbilicus (Gartner) Gartner (CO-1 borehole, N+); i Umbilicosphaera jafari Müller (TO-2 borehole, NII); j Umbilicosphaera rotula (Kamptner) Varol (TO-2 borehole, NII).
Fig. 2 in Upper Burdigalian-Middle Sarmatian Calcareous Nannofossils From Totea-Văleni Area (Getic Depression, Romania)
Fig. 2 Lithology and biostratigraphy of the upper Burdigalian-middle Sarmatian deposits of the Totea - Colțești - Rădinești - Văleni area.
Fig. 1 a in Upper Burdigalian-Middle Sarmatian Calcareous Nannofossils From Totea-Văleni Area (Getic Depression, Romania)
Fig. 1 a Geological Map of Romania, scale 1: 1,000,000. Printed by the Geological Institute of Romania (1978), showing the location of the investigated area; b Location of the studied drillings on the scale 1:200,000 Pitești Sheet (Mihăilă et al., 1967) of the Geological Map of Romania, printed by the Geological Institute of Romania.
Fig.3. Relation between depression level expresed Fig.4 in Oxidative Stress Indicators, Depression And Qua Lity Of Live L Evel S In Co Rona Ry Heart Disease Patients
Fig.3. Relation between depression level expresed Fig.4. Box plot displaying the distribution of the in Geriatric depression score points and oxidative data showing differences in Geriatric depression stress parameter (GPx) score points in primary and recurrent SCHD patients according to gender.
Fig.1. Relation between depression level expresed Fig.2 in Oxidative Stress Indicators, Depression And Qua Lity Of Live L Evel S In Co Rona Ry Heart Disease Patients
Fig.1. Relation between depression level expresed Fig.2. Relation between depression level expresed in Geriatric depression score points andlevelof in Geriatric depression score points and oxidative life Quality. stress parameter (MDA).
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.