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64 results for “Dictyostelium discoideum”
Data from: Fruiting bodies of the social amoeba Dictyostelium discoideum increase spore transport by Drosophila
Background: Many microbial phenotypes are the product of cooperative interactions among cells, but their putative fitness benefits are often not well understood. In the cellular slime mold Dictyostelium discoideum, unicellular amoebae aggregate when starved and form multicellular fruiting bodies in which stress-resistant spores are held aloft by dead stalk cells. Fruiting bodies are thought to be adaptations for dispersing spores to new feeding sites, but this has not been directly tested. Here we experimentally test whether fruiting bodies increase the rate at which spores are acquired by passing invertebrates. Results: Drosophila melanogaster accumulate spores on their surfaces more quickly when exposed to intact fruiting bodies than when exposed to fruiting bodies physically disrupted to dislodge spore masses from stalks. Flies also ingest and excrete spores that still express a red fluorescent protein marker. Conclusions: Multicellular fruiting bodies created by D. discoideum increase the likelihood that invertebrates acquire spores that can then be transported to new feeding sites. These results thus support the long-hypothesized dispersal benefits of altruism in a model system for microbial cooperation.
Data from: The rate and effects of spontaneous mutation on fitness traits in the social amoeba, Dictyostelium discoideum
We performed a mutation accumulation (MA) experiment using the social amoeba Dictyostelium discoideum to estimate the rate and distribution of effects of spontaneous mutations affecting eight putative fitness traits. We found that the per generation mutation rate for most fitness components is 0.0019 mutations per haploid genome per generation, or larger. This rate is an order of magnitude higher than estimates for fitness components in the unicellular eukaryote Saccharomyces cerevisiae, even though the base-pair substitution rate is two orders of magnitude lower. The high rate of fitness-altering mutations observed in this species may be partially explained by a large mutational target relative to Saccharomyces cerevisiae. Also, fitness-altering mutations may occur primarily at simple sequence repeats, which are common throughout the genome, including in coding regions, and may represent a target that is particularly likely to give fitness effects upon mutation. The majority of mutations had deleterious effects on fitness, but there was evidence for a substantial fraction, up to 40%, being beneficial for some of the putative fitness traits. Competitive ability within the multicellular slug appears to be under weak directional selection, perhaps reflecting the fact that slugs are sometimes, but not often, comprised of multiple clones in nature. Evidence for pleiotropy among fitness components across MA lines was absent, suggesting that mutations tend to act on single fitness components.
Data from: Sentinel cells, symbiotic bacteria, and toxin resistance in the social amoeba Dictyostelium discoideum
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Data from: The rate and effects of spontaneous mutation on fitness traits in the social amoeba, Dictyostelium discoideum
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Data from: Sex ratio and gamete size across eastern North America in Dictyostelium discoideum, a social amoeba with three sexes
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Data from: Fruiting bodies of the social amoeba Dictyostelium discoideum increase spore transport by Drosophila
Open the record for dataset details and reuse information.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 24h p.i. (comparison experiment)
GEO Series GSE50696. Dictyostelium discoideum. 19 samples. Type: Expression profiling by array.
Global characterization of the Dicer-like protein DrnB roles in miRNA biogenesis in the social amoeba Dictyostelium discoideum
GEO Series GSE111592. Dictyostelium discoideum AX2. 16 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
The long non-coding RNA transcriptome of Dictyostelium discoideum development
GEO Series GSE90829. Dictyostelium discoideum. 23 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 24h p.i. (timecourse experiment)
GEO Series GSE50964. Dictyostelium discoideum. 6 samples. Type: Expression profiling by array.
Transcription and loop extrusion cooperatively shape the 3D genome of developing slime mold Dictyostelium discoideum [RNA-seq]
GEO Series GSE246367. Dictyostelium discoideum. 8 samples. Type: Expression profiling by high throughput sequencing.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. the L. pneumophila delta DotA mutant 24h p.i.
GEO Series GSE50536. Dictyostelium discoideum. 4 samples. Type: Expression profiling by array.
Functional Characterisation of the Ubiquitin-like Core Autophagy Protein ATG12 in Dictyostelium discoideum
GEO Series GSE123780. Dictyostelium discoideum. 36 samples. Type: Expression profiling by high throughput sequencing.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 3h p.i. (timecourse experiment)
GEO Series GSE50962. Dictyostelium discoideum. 6 samples. Type: Expression profiling by array.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 48h p.i. (timecourse experiment)
GEO Series GSE50965. Dictyostelium discoideum. 6 samples. Type: Expression profiling by array.
MicroRNAs in Amoebozoa: Deep sequencing of the small RNA population in the social amoeba Dictyostelium discoideum reveals developmentally regulated microRNAs
GEO Series GSE38361. Dictyostelium discoideum. 3 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Allorecognition, via TgrB1 and TgrC1, mediates the transition from unicellularity to multicellularity in the social amoebae Dictyostelium discoideum
GEO Series GSE68063. Dictyostelium discoideum. 12 samples. Type: Expression profiling by high throughput sequencing.
Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum
GEO Series GSE61914. Dictyostelium discoideum. 67 samples. Type: Expression profiling by high throughput sequencing.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 1h p.i. (timecourse experiment)
GEO Series GSE50963. Dictyostelium discoideum. 6 samples. Type: Expression profiling by array.
Functional Characterisation of the Core Autophagy Protein ATG5 in Dictyostelium discoideum
GEO Series GSE142251. Dictyostelium discoideum. 24 samples. Type: Expression profiling by high throughput sequencing.
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