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Fig. 6 in Antennal sensillum morphology and electrophysiological responses of olfactory receptor neurons in trichoid sensilla of the diamondback moth (Lepidoptera: Plutellidae)

Fig. 6. Detailed surface morphology of sensilla coeloconica (A, B and C) and sensilla auricillica (D, E and F) of the antennae of Plutela xylostella.

Fig. 8 in Antennal sensillum morphology and electrophysiological responses of olfactory receptor neurons in trichoid sensilla of the diamondback moth (Lepidoptera: Plutellidae)

Fig. 8. Traces of the response spikes of the olfactory receptor neurons (ORNs) in class A trichoid sensilla of female Plutella xylostella in response to various green leaf volatiles. Each trace shows the extracellular signals for a period of 5 s. The scale bar indicates the stimulation for 0.1 s with corresponding test stimulus.

Fig. 9 in Antennal sensillum morphology and electrophysiological responses of olfactory receptor neurons in trichoid sensilla of the diamondback moth (Lepidoptera: Plutellidae)

Fig. 9. Traces of the response spikes of the olfactory receptor neurons (ORNs) in class D trichoid sensilla of female Plutella xylostella in response to geraniol and (±)-linalool. Each trace shows the extracellular signals for a period of 5 s. The scale bar indicates the stimulation for 0.1 s with corresponding test stimulus.

Fig. 1 in Antennal sensillum morphology and electrophysiological responses of olfactory receptor neurons in trichoid sensilla of the diamondback moth (Lepidoptera: Plutellidae)

Fig. 1. The length (triangles) and diam (squares) of each flagellar subsegment of the antennae of female (A) and male (B) diamondback moth, Plutella xylostella. Data obtained from 3 females and 5 males.

Fig. 5 in Antennal sensillum morphology and electrophysiological responses of olfactory receptor neurons in trichoid sensilla of the diamondback moth (Lepidoptera: Plutellidae)

Fig. 5. Detailed surface morphology of the sensilla trichodea (A, B, C and D) and sensilla chaetica (A, B and E) of the antennae of Plutela xylostella.

opencc-by-4.0Jul 2024View details →

Electrophysiological recordings from human-derived cardiomyocytes in the form of MEA (microelectrode array) recordings

The electrophysiological data were acquired using standard software for MEA acquisition, such as the programs provided with the used MEA acquisition system coupled with the SiMulTox prototype.

opencc-by-4.0Jan 2018View details →

Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20170127_03

This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> . General description. These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20170127_03". Filtering. The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate. File format. The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification. Datasets. A few of the relevant dataset paths are listed here for convenience. In the below, n refers to the number of recording channels and k refers to the number of samples. <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.

BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 100 Schizophrenia Patients to 48 Patients with Major Depression -Figure 4. Histogram age distributions of the 100 Schizophrenia patients illustrating clusters of patients at 20, 30, 40, and 50 years old.

The figure below is a histogram distribution of the ages of one hundred Schizophrenia patients in this study. There appears to be a cyclical peak every ten-years cycles at 20, 30, 40, and 50-year-old patients. This may suggest a recent finding that CD8 T cells, which play a pivotal role in mediating long-term immunity to Toxoplasma, are down-regulated in schizophrenia patients (Bhadra et al., 2013). Based on the aforementioned statements, a vaccine for Toxoplasmosis may be difficult to achieve, but the treatment and screening possibilities in patients with psychosis are available today.

BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 100 Schizophrenia Patients to 48 Patients with Major Depression -Figure 3. Resulting comparisons isolating the Dopamine D2 Mesolimbic Pathway

Moreover, a study in Prague identified that Toxoplasmosis triggers schizophrenia in predisposed subjects (Flegr et al., 2014). It may very well be that the Toxoplasmosis parasite increasing dopamine secretions in the frontal lobes may very well lead to decreased cerebral volumes. Cat feces, sexual contact, and eating raw or undercooked pork are well known transmitters of the Toxoplasmosis parasite and may be advisable that patients take precautions of the possibility of these triggering symptoms of psychosis with these possible routes of infection. Another adjunct to Atypical Antipsychotics may be to treat the potential cerebral Toxoplasmosis infection with Cotrimoxazole or Pyrimethamine/Clindamycin.

BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 100 Schizophrenia Patients to 48 Patients with Major Depression -Figure 2. Resting State neuroimaging findings illustrating the action of atypical antipsychotics on postsynaptic dopamine D2

Contrastingly, the results of the one-hundred males and females diagnosed with Schizophrenia compared to the thirty-two females diagnosed with Major Depressive Disorder or Depressive Episodes. The one-hundred male and female Schizophrenia patients had an average age of 32-years-old and a Standard Deviation of 11.8-years. Whereas, the Depressive Episode and Major Depressive Disorder females had an average age of 50-years old and a Standard Deviation of 11.7-years. The statistically significant neuroimaging results identified the Delta (1.5–6 Hz) frequency band at the neuroanatomical location of the region of the Superior Frontal Gyrus (p=0.007; t=2.08, BA 10, X=25, Y=55, Z=30) with greater neuronal oscillations and synchrony in the one-hundred males and females diagnosed with Schizophrenia than the thirty-two females diagnosed with Depressive Episodes and Major Depressive Disorder.

BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 12 Anorexia Nervosa Patients to 12 Controls-Figure 2: All axial slices of sLORETA imaging results of Resting State EEG Supra-Threshold Voxels in both the Parahippocampal (limbic) and Fusiform (temporal) Gyri illustrating decreased neuronal activity in the Anorexia Nervosa patients.

Results from the sLORETA imaging indicates decreased neuronal activation within the Left Fusiform Gyrus located in the Temporal lobe and Parrahippocampal gyrus, which is located in the Limbic Lobe (Table 1). This correlates with other fMRI findings where patients with early onset AN have exhibited reduced unilateral blood flow in the temporal lobe. The Parahippocampal and Fusiform Gyri are centers that process emotions. Previous studies in which these regions have shown activation involve women that have distorted perceptions of their bodies from a cognitive perspective (Santel et al., 2006). It is apparent from our findings that the Fusiform Gyrus may play a vital role in the processing of visual appearance of the human body. There is also a correlation with the somatosensory limbic pathway in the limbic lobe, due to the similarity of function.

BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 100 Schizophrenia Patients to 48 Patients with Major Depression -Figure 1. Group comparisons designed for isolating the mesolimbic Dopamine D2

All patients diagnosed with Schizophrenia were medicated with atypical antipsychotics, Olanzapine (dose 5mg/day to 20mg/day) or Risperidone (dose 1mg/day to 4mg/day) blocking both Dopamine D2 and Serotonin 5-HT2 receptors. Whereas, all of the patients diagnosed with Major Depression or Depressive Episode were medicated with Sertraline (50mg/day to 200mg/day maximum dose) or Citalopram (20mg/day to 40mg/day maximum dose). This research protocol was approved by the Bioethical Commission of the Medical University of Lublin.

BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 12 Anorexia Nervosa Patients to 12 Controls-Figure 1: sLORETA imaging results of Resting State EEG Supra-Threshold Voxels in both the Parahippocampal (limbic) and Fusiform (temporal) Gyri illustrating decreased neuronal activity in the Anorexia Nervosa patients relative to Control participants

The findings of the sLORETA analysis indicated that, the difference is statistically significant (p=0.03) using a one-tailed t-test: Anorexia > Controls. The brains of the patients with Anorexia Nervosa illustrated decreased neuronal activity in the Left Fusiform Gyrus and the Left Parahippocampal Gyrus (p=0.03) in the resting-state brains when Anorexia Patients were sitting for 3min, as compared to the Controls sitting for 3minutes.

opencc-by-4.0Jan 2018View details →

Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20170124_01

This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> . General description. These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20170124_01". Filtering. The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate. File format. The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification. Datasets. A few of the relevant dataset paths are listed here for convenience. In the below, n refers to the number of recording channels and k refers to the number of samples. <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.

opencc-by-4.0Feb 2018View details →

Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20170123_02

This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> . General description. These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20170123_02". Filtering. The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate. File format. The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification. Datasets. A few of the relevant dataset paths are listed here for convenience. In the below, n refers to the number of recording channels and k refers to the number of samples. <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.

opencc-by-4.0Jun 2018View details →

Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161220_02

This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> . General description. These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161220_02". Filtering. The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate. File format. The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification. Datasets. A few of the relevant dataset paths are listed here for convenience. In the below, n refers to the number of recording channels and k refers to the number of samples. <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.

Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161207_02

This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> . General description. These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161207_02". Filtering. The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate. File format. The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification. Datasets. A few of the relevant dataset paths are listed here for convenience. In the below, n refers to the number of recording channels and k refers to the number of samples. <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.

Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161212_02

This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> . General description. These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161212_02". Filtering. The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate. File format. The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification. Datasets. A few of the relevant dataset paths are listed here for convenience. In the below, n refers to the number of recording channels and k refers to the number of samples. <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.

Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161206_02

This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> . General description. These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161206_02". Filtering. The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate. File format. The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification. Datasets. A few of the relevant dataset paths are listed here for convenience. In the below, n refers to the number of recording channels and k refers to the number of samples. <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.

Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161026_03

This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> . General description. These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161026_03". Filtering. The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate. File format. The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification. Datasets. A few of the relevant dataset paths are listed here for convenience. In the below, n refers to the number of recording channels and k refers to the number of samples. <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.