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116 results for “Enterococcus”
Oral cholestyramine prevents the enrichment of diverse daptomycin-resistance mutations in intestinal Enterococcus faecium populations
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Insertion sequences and other mobile elements associated with antibiotic resistance genes in Enterococcus isolates from an inpatient with prolonged bacteremia.
<p>Insertion sequences (ISs) and other transposable elements are associated with the mobilization of antibiotic resistance determinants and the modulation of pathogenic characteristics. In this work, we aimed to investigate the association between ISs and antibiotic resistance genes, and their role in dissemination and modification of the antibiotic resistant phenotype. To that end, we leveraged fully resolved <em>Enterococcus faecium</em> and <em>Enterococcus faecalis</em> genomes of isolates collected over five days from an inpatient with prolonged bacteremia. Isolates from both species harbored similar IS family content but showed significant species-dependent differences in copy number and arrangements of ISs throughout their replicons. Here, we describe two inter-specific IS-mediated recombination events and IS-mediated excision events in plasmids of <em>E. faecium</em> isolates. We also characterize a novel arrangement of the ISs in a Tn1546-like transposon in <em>E. faecalis</em> isolates likely implicated in a vancomycin genotype-phenotype discrepancy. Furthermore, an extended analysis revealed a novel association between daptomycin resistance mutations in <em>liaSR</em> genes and a putative composite transposon in<em> E. faecium</em>, offering a new paradigm for the study of daptomycin resistance and novel insights into the dissemination of daptomycin resistance. In conclusion, our study highlights the role ISs and other transposable elements play in the rapid adaptation and response to clinically relevant stresses such as aggressive antibiotic treatment in enterococci.</p>
Wildtype Escherichia coli and Enterococcus lactis isolated from HK WWTP
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A Trial of Encapsulated Fecal Microbiota for Vancomycin Resistant Enterococcus Decolonization
ClinicalTrials.gov study NCT03063437. IPD Sharing: NO. Countries: 1. Publications: 0.
Timecourse of Enterococcus faecalis infection of HUC cells
GEO Series GSE5988. Homo sapiens. 8 samples. Type: Expression profiling by array.
The impact of iron depletion on the transcriptome of Enterococcus faecalis
GEO Series GSE221057. Enterococcus faecalis OG1RF. 6 samples. Type: Expression profiling by high throughput sequencing.
Effect of in vitro co-culturing of Lactobacillus crispatus on gene expression of Enterococcus faecalis OG1RF
GEO Series GSE279275. Enterococcus faecalis OG1RF. 6 samples. Type: Expression profiling by high throughput sequencing.
The PerA regulon in Enterococcus faecalis
GEO Series GSE31538. Escherichia coli CFT073; Enterococcus faecalis V583; Escherichia coli O157:H7 str. Sakai; Enterococcus faecalis; Bacillus anthracis; Escherichia coli str. K-12 substr. MG1655; Escherichia coli O157:H7 str. EDL933; Bacteroides thetaiotaomicron VPI-5482; Salmonella enterica subsp. enterica serovar Typhimurium str. LT2. 12 samples. Type: Expression profiling by array.
Transcriptome Analysis of Caenorhabditis elegans Lacking Heme Peroxidase SKPO-1 Reveals an Altered Response to Enterococcus faecalis
GEO Series GSE153088. Caenorhabditis elegans. 14 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide Analysis of Enterococcus faecalis OG1RF(pCF10) Gene Expression During Infection
GEO Series GSE58467. Enterococcus faecalis. 2 samples. Type: Expression profiling by high throughput sequencing.
Purine and carbohydrate availability drive Enterococcus faecalis fitness in wound infections [dataset 1]
GEO Series GSE206749. Enterococcus faecalis. 8 samples. Type: Expression profiling by high throughput sequencing.
Purine and carbohydrate availability drive Enterococcus faecalis fitness in wound infections [dataset 2]
GEO Series GSE206750. Enterococcus faecalis. 12 samples. Type: Expression profiling by high throughput sequencing.
The regulatory RNA Ern0160 is involved in pathogenicity of Enterococcus faecium
GEO Series GSE239910. Enterococcus faecium Aus0004. 8 samples. Type: Expression profiling by high throughput sequencing.
TnSeq of Enterococcus faecalis OG1RF Tn mutants in biofilm and planktonic samples
GEO Series GSE171419. Enterococcus faecalis OG1RF. 24 samples. Type: Other.
(p)ppGpp promotes Enterococcus faecalis virulence in a murine model of catheter-associated urinary tract infection
GEO Series GSE131749. Enterococcus faecalis OG1RF. 6 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide Analysis of Enterococcus faecalis OG1RF Gene Expression During Infection
GEO Series GSE22391. Enterococcus faecalis V583; Enterococcus faecalis OG1RF. 12 samples. Type: Expression profiling by array.
Arginine impacts aggregation, biofilm formation, and antibiotic susceptibility in Enterococcus faecalis
GEO Series GSE268264. Enterococcus faecalis. 8 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profile at single cell level from untreated and Enterococcus faecalis-infected skin wounds
GEO Series GSE229257. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Next Generation Sequencing Facilitates Quantitative Analysis of Enterococcus durans A8-1 cells fermentation at MRS medium and MRS medium supplied with 60mg/L Na2SeO3
GEO Series GSE188295. Enterococcus durans. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic profiling of human placental trophoblasts in response to Enterococcus faecalis invasion
GEO Series GSE75626. Homo sapiens. 4 samples. Type: Expression profiling by array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.