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36 results for “FST”
Data from: Evaluation of demographic history and neutral parameterization on the performance of Fst outlier tests
FST outlier tests are a potentially powerful way to detect genetic loci under spatially divergent selection. Unfortunately, the extent to which these tests are robust to non-equilibrium demographic histories has been under-studied. We developed a landscape-genetics simulator to test the effects of isolation by distance (IBD) and range expansion on FST outlier methods. We evaluated the two most commonly used methods for the identification of FST outliers (FDIST2 and BayeScan, which assume samples are evolutionarily independent) and two recent methods (FLK and Bayenv2, which estimate and account for evolutionary non-independence). Parameterization with a set of neutral loci ("neutral parameterization") always improved the performance of FLK and Bayenv2, while neutral parameterization caused FDIST2 to actually perform worse in the cases of IBD or range expansion. BayeScan was improved when the prior odds on neutrality was increased, regardless of the true odds in the data. On their best performance, however, the widely-used methods had high false-positive rates for IBD and range expansion and were outperformed by methods that accounted for evolutionary non-independence. In addition, default settings in FDIST2 and BayeScan resulted in many false positives under balancing selection. However, all methods did very well if a large set of neutral loci is available to create empirical p-values. We conclude that in species that exhibit IBD or have undergone range expansion, many of the published FST outliers based on FDIST2 and BayeScan are probably false positives, but FLK and Bayenv2 show great promise for accurately identifying loci under spatially-divergent selection.
Post Exercise Recovery and FST
ClinicalTrials.gov study NCT06522230. IPD Sharing: NO. Countries: 0. Publications: 3.
Multi-component Family Support Tool Intervention (FST)
ClinicalTrials.gov study NCT05019261. IPD Sharing: YES. Countries: 1. Publications: 0.
Data from: Background selection and FST: consequences for detecting local adaptation
Open the record for dataset details and reuse information.
Data from: QST FST comparisons with unbalanced half-sib designs
Open the record for dataset details and reuse information.
Data from: Evaluation of demographic history and neutral parameterization on the performance of Fst outlier tests
Open the record for dataset details and reuse information.
Examination of E. faecalis toxin-antitoxin (TA) toxin Fst function utilizing a pheromone-inducible expression vector with tight repression and large dynamic range
GEO Series GSE96072. Enterococcus faecalis. 4 samples. Type: Expression profiling by high throughput sequencing.
FST-100 in the Treatment of Acute Viral Conjunctivitis
ClinicalTrials.gov study NCT01461954. IPD Sharing: Not stated. Countries: 2. Publications: 0.
FST-100 in the Treatment of Acute Adenoviral Conjunctivitis
ClinicalTrials.gov study NCT01470664. IPD Sharing: Not stated. Countries: 2. Publications: 0.
FST-201 In The Treatment of Acute Fungal Otitis Externa
ClinicalTrials.gov study NCT00945646. IPD Sharing: Not stated. Countries: 1. Publications: 0.
FST-100 Ophthalmic Suspension in Acute Adenoviral Conjunctivitis
ClinicalTrials.gov study NCT00941486. IPD Sharing: Not stated. Countries: 1. Publications: 0.
PD-1 Inhibitor Combined With Progesterone Treatment in FST for Patients With MMRd Endometrial Cancer
ClinicalTrials.gov study NCT06549855. IPD Sharing: NO. Countries: 1. Publications: 0.
FST-201 In The Treatment of Acute Otitis Externa
ClinicalTrials.gov study NCT00945802. IPD Sharing: Not stated. Countries: 1. Publications: 0.
FST-201 in the Treatment of Acute Otitis Externa
ClinicalTrials.gov study NCT00961675. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The differential gene expression of the dentate gyrus between WT and KO mice as well as between Fst knockout and overexpressing mice
GEO Series GSE163449. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
miRNA expression data in MCF-7 breast cancer Cell line post BCAS2 and FST knockdown
GEO Series GSE89390. Homo sapiens; synthetic construct. 9 samples. Type: Non-coding RNA profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.