Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
241
datasets available to search
ShareScore release 0.7.1
Dataset results
241 results for “Food Safety”
Single-center, double-blind, randomized, placebo-controlled, single andmultiple dose escalation study to assess safety and tolerability and pharmacokinetics of HRX215 in healthy male volunteers under food and fasting conditions
<p><a name="_Hlk123284665"></a><a name="_Hlk135557103"></a><span><span>Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. </span></span><span><span>Therapies to restore hepatocyte regeneration are lacking, making liver transplantation the only curative option for end stage liver disease. We here report on the structure-based development and characterization (NMR-spectroscopy) of first-in-class small molecule inhibitors of the dual specific kinase MKK4 (MKK4i). MKK4i increased liver regeneration upon hepatectomy in murine and porcine models, allowed for survival of pigs in a lethal 85% hepatectomy model and showed antisteatotic and antifibrotic effects in liver disease mouse models. A first-in-human phase I trial (EudraCT 2021-000193-28) with the clinical candidate HRX215 was conducted and revealed excellent safety and pharmacokinetics. Clinical trials to probe HRX215 for prevention/treatment of liver failure after extensive oncological liver resections or after transplantation of small grafts are warranted.</span></span></p>
Food Safety and Online Food Delivery Apps Post Covid-19
<p>The data collection method that will be used will be questionnaires that will be made available online and written in Indonesian. Questionnaires were distributed during the post outbreak of COVID-19</p>
Report on the identification of stakeholder measurement needs for food safety
Open the record for dataset details and reuse information.
Listeria - Case studies in Food Safety
<p>Webinar - Listeria - Case studies in Food Safety</p>
Survey: Motivation, capability and opportunity for food safety messages
<p><strong>Background</strong></p> <p>A significant part of foodborne infections is caused by food eaten at home, and food safety messages are given to help consumers mitigate risk. The World Health Organisation (WHO) "Five Keys to Safer Food", developed about 20 years ago has been used with success worldwide to provide general advice on how to prepare food safely.</p> <p><strong>Scope and Approach</strong></p> <p>In this commentary, we discuss how food safety messages could be updated using a holistic approach built on implementation science, considering new food consumption patterns and insights from natural and social sciences. A stepwise approach for developing and evaluating food safety messages, performed in the European project SafeConsume, is presented. The top pathogen-food combinations associated with foodborne disease in Europe combined with common consumer practices were used to identify behaviours potentially leading to illness. Food safety messages were suggested and evaluated for understanding as well as capability, opportunity and motivation in an expert survey.</p> <p><strong>Key Findings and Conclusions</strong></p> <p>Overall, the food safety topics prioritised overlapped with those from WHO. The opportunity and motivation for changing behaviour, (e.g. choose pasteurised egg) were identified as important restrictions for uptake of messages. Also, the large variation in basic terminology, such as "thoroughly cooked" is a challenge. Therefore, to enhance the capability, there is a need to be very specific, without excluding other safe alternatives or making lengthy <a>explanations</a>. The food safety messages suggested by the expert group were evaluated as more likely to the implemented among domestic cooks and resulting in safer practices than corresponding WHO messages.</p>
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects
ClinicalTrials.gov study NCT02058407. IPD Sharing: YES. Countries: 1. Publications: 1.
Placebo-Controlled Clinical Nutrition Study of the Safety and Metabolic Effects of Two Medical Foods in Type 2 Diabetes
ClinicalTrials.gov study NCT03893422. IPD Sharing: NO. Countries: 1. Publications: 1.
2-part Study to Assess Safety, Pharmacokinetics & Pharmacodynamics of CC-220 & Effect of Food on CC-220 in Healthy Subjects
ClinicalTrials.gov study NCT01733875. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP1617 in Healthy Adult Non-Asian and Japanese Subjects Including Assessment of a Food Effect
ClinicalTrials.gov study NCT04077879. IPD Sharing: NO. Countries: 1. Publications: 1.
Safety and Food Effect on Single-Dose Bioavailability of F-02-2-Na in Healthy Adult Subjects
ClinicalTrials.gov study NCT07346027. IPD Sharing: NO. Countries: 1. Publications: 4.
Study to Evaluate Pharmacokinetics, Food Effect, Safety and Efficacy of Oral Azacitidine
ClinicalTrials.gov study NCT01519011. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Evaluating the Safety, Tolerability, Pharmacokinetics, and Effect of Food of Lucid-21-302 in Healthy Volunteers
ClinicalTrials.gov study NCT05821387. IPD Sharing: NO. Countries: 1. Publications: 2.
Knowledge,Attitude and Practice of Food Handleres About Food Safety
ClinicalTrials.gov study NCT04314063. IPD Sharing: NO. Countries: 1. Publications: 3.
Study in Chinese Healthy Adults to Evaluate the Safety, Tolerability and Pharmacokinetics on ZSP1601, and the Effect of Food on ZSP1601 Pharmacokinetics
ClinicalTrials.gov study NCT03392779. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Dose Escalation Study to Assess PK, Safety and Tolerability of INC280 When Taken With Food in cMET Dysregulated Advanced Solid Tumors.
ClinicalTrials.gov study NCT02925104. IPD Sharing: NO. Countries: 8. Publications: 1.
Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GS-9674 (Cilofexor), and the Effect of Food on GS-9674 Pharmacokinetics and Pharmacodynamics
ClinicalTrials.gov study NCT02654002. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety,PK/PD, Food Effect Study of Orally Administered HM71224 in Healthy Adult Male Volunteers
ClinicalTrials.gov study NCT01765478. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Investigate Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of JNJ-54175446 in Healthy Participants
ClinicalTrials.gov study NCT02475148. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study to Evaluate Safety, Tolerability, Pharmacokinetics and the Food Effect on PK of ASC10 Tablets in Healthy Subjects
ClinicalTrials.gov study NCT05523141. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Trial to Investigate the Effects of Food on the Pharmacokinetics and Safety of Orally Administered Radotinib
ClinicalTrials.gov study NCT06461078. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.