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35
datasets available to search
ShareScore release 0.9.0
Dataset results
35 results for “GRN”
A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)
ClinicalTrials.gov study NCT06064890. IPD Sharing: NO. Countries: 8. Publications: 0.
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)
ClinicalTrials.gov study NCT05262023. IPD Sharing: NO. Countries: 12. Publications: 0.
A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes
ClinicalTrials.gov study NCT04747431. IPD Sharing: NO. Countries: 5. Publications: 0.
Phase 1 Study of GRN-1201 in HLA-A*02 Subjects With Resected Melanoma
ClinicalTrials.gov study NCT02696356. IPD Sharing: NO. Countries: 1. Publications: 0.
Study in Asymptomatic GRN-FTD Patients to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001
ClinicalTrials.gov study NCT06705192. IPD Sharing: NO. Countries: 2. Publications: 0.
First-in-Human Evaluation of GRN-300 in Subjects With Recurrent Ovarian, Primary Peritoneal, and Fallopian Tube Cancers.
ClinicalTrials.gov study NCT04711161. IPD Sharing: NO. Countries: 1. Publications: 0.
A key netwrok hub gene GRN confers chemo resistance in H2081 SCLC cells.
GEO Series GSE245123. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
TMEM106B reduction or partial depletion does not rescue GRN haploinsufficiency in mouse and iPSC-derived human microglia cell models [Human iMG]
GEO Series GSE237104. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.
Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation
GEO Series GSE188498. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
TMEM106B reduction or partial depletion does not rescue GRN haploinsufficiency in mouse and iPSC-derived human microglia cell models.
GEO Series GSE237107. Homo sapiens; Mus musculus. 78 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profile of brain tissue from wildtype and GRN knock-out mice treated with an AAV driving expression of PTV-Progranulin in the liver
GEO Series GSE260606. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
TMEM106B reduction or partial depletion does not rescue GRN haploinsufficiency in mouse and iPSC-derived human microglia cell models [Mouse ASO]
GEO Series GSE237105. Mus musculus. 39 samples. Type: Expression profiling by high throughput sequencing.
TMEM106B reduction or partial depletion does not rescue GRN haploinsufficiency in mouse and iPSC-derived human microglia cell models [Mouse MG]
GEO Series GSE237106. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to the article "GRN- /- IPSC-DERIVED CORTICAL NEURONS RECAPITULATE THE PATHOLOGICAL FINDINGS OF BOTH FRONTOTEMPORAL LOBAR DEGENERATION AND NEURONAL CEROIDOLIPOFUSCINOSIS"
<p>THE DATASET CONTAINS .XLSX FILES REPORTING BIOCHEMICAL DATA (DENSITOMETRIC ANALYSIS) AND IMMUNOHISTOCHEMICAL DATA (MORPHOMETRIC ANALYSIS AND COUNTING) </p>
Rescue of TDP-43 and neuronal pathologies by peripheral AAV-mediated expression of brain-penetrant progranulin in a mouse model of GRN-linked frontotemporal lobar degeneration
GEO Series GSE235515. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.