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32
datasets available to search
ShareScore release 0.9.0
Dataset results
32 results for “Hotspot mutations”
Pathogenic DICER1 RNase IIIb Hotspot Mutation Induces 3p-miRNA Gain-of-Function via Argonaute Strand Switch [miR-seq]
GEO Series GSE279556. Mus musculus; Homo sapiens. 26 samples. Type: Non-coding RNA profiling by high throughput sequencing.
DICER1 hotspot mutations cause defective miRNA processing
GEO Series GSE40965. Mus musculus. 28 samples. Type: Expression profiling by array.
A functional genomics process for systematic dissection and mutation-specific target discovery in breast cancer PIK3CA hotspot mutations
GEO Series GSE247822. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
GEO Series GSE179409. Mus musculus. 6 samples. Type: Expression profiling by array.
Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations
GEO Series GSE225828. Homo sapiens. 15 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Cancer hotspot mutations rewire ERK2 specificity by selective exclusion of docking interactions
GEO Series GSE286340. Homo sapiens. 23 samples. Type: Other.
Engineering oncogenic hotspot mutations on SF3B1 via CRISPR-directed PRECIS mutagenesis
GEO Series GSE231387. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Endogenous expression of the R-RAS2 GTPase carrying the Q72L hotspot mutation is relevant for the tumorigenic phenotype of cancer cells
GEO Series GSE201472. Homo sapiens. 6 samples. Type: Expression profiling by array.
A functional genomics process for systematic dissection and mutation-specific target discovery in breast cancer PIK3CA hotspot mutations [ATAC-Seq]
GEO Series GSE247821. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A hotspot mutation p.L162R in IKZF3 drives leukemogenesis via transcriptional dysregulation
GEO Series GSE143711. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Targeting of DNMT3A hotspot mutations in Clonal Hematopoiesis and Acute Myeloid Leukemia
GEO Series GSE146907. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
datset related to article "Mutations associated with hypokalemic periodic paralysis: from hotspot regions to complete analysis of CACNA1S and SCN4A genes."
<p>VCF files of mutated HypoPP patients analysed by the NGS panel.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.