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ShareScore release 0.9.0
Dataset results
79 results for “Human diet”
Transcriptomics driven metabolic pathway analysis reveals similar metabolic alterations in diet- and chemical-induced mouse NASH model and human
GEO Series GSE230639. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome
GEO Series GSE48537. Dorea longicatena DSM 13814; [Clostridium] scindens ATCC 35704; Faecalibacterium prausnitzii M21/2; Collinsella aerofaciens ATCC 25986; Thomasclavelia spiroformis DSM 1552; Bacteroides thetaiotaomicron VPI-5482; Blautia obeum ATCC 29174; [Ruminococcus] torques ATCC 27756; Bacteroides caccae ATCC 43185; Agathobacter rectalis ATCC 33656; Bacteria; Bacteroides ovatus ATCC 8483; Bacteroides uniformis ATCC 8492; Phocaeicola vulgatus ATCC 8482; Parabacteroides distasonis ATCC 8503; Bacteroides cellulosilyticus; Bacteroides sp. WH2. 895 samples. Type: Expression profiling by high throughput sequencing; Other; Expression profiling by array.
Hyperandrogenemia and western-style diet act synergistically on transcription and DNA methylation in visceral adipose tissue of a non-human primate model [RRBS]
GEO Series GSE124708. Macaca mulatta. 24 samples. Type: Methylation profiling by high throughput sequencing.
Gene Expression in the Human Mammary Epithelium in response to consumption of high fat (H-FAT) and high carbohdyrate (H-CHO) diets.
GEO Series GSE51874. Homo sapiens. 28 samples. Type: Expression profiling by array.
Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome (RNA-Seq)
GEO Series GSE48993. Bacteria; Bacteroides cellulosilyticus. 116 samples. Type: Expression profiling by high throughput sequencing.
Diet rapidly and reproducibly alters the human gut microbiome
GEO Series GSE46761. human gut metagenome. 59 samples. Type: Expression profiling by high throughput sequencing.
miRNAs in human subcutaneous adipose tissue: Effects of weight loss induced by hypo-caloric diet and exercise
GEO Series GSE87103. Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Mus musculus; Rattus norvegicus; Murid betaherpesvirus 1; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Merkel cell polyomavirus; Human alphaherpesvirus 2; Murid gammaherpesvirus 4; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Betapolyomavirus hominis. 24 samples. Type: Non-coding RNA profiling by array.
Genetic Effects in Response to Exercise and Diet-induced Weight-loss in Human Skeletal Muscle Tissues
GEO Series GSE282733. Homo sapiens. 108 samples. Type: Expression profiling by high throughput sequencing.
Ketogenic Diet dependent Immunometabolic Reprogramming of human T cells
GEO Series GSE158407. Homo sapiens. 56 samples. Type: Expression profiling by high throughput sequencing.
Linking the effects of helminth infection, diet and the gut microbiota with human whole-blood signatures
GEO Series GSE137338. Homo sapiens. 111 samples. Type: Expression profiling by high throughput sequencing.
Butyrate protects against diet-induced liver fibrosis and suppresses non-canonical TGF-β signaling in human stellate cells
GEO Series GSE179395. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic analysis of liver mRNA from TSP-1 KO and WT mice fed with normal diet or choline deficient amino acid defined diet (CDAHFD, human NASH model)
GEO Series GSE120977. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Small-RNA sequencing of human urinary extracellular vesicles reveals association of high sodium diet with renal pro-inflammatory pathways
GEO Series GSE288935. Homo sapiens. 36 samples. Type: Non-coding RNA profiling by high throughput sequencing.
High- and low-protein diet: effects on human hepatic fat content, autophagy, mitochondrial function and fat metabolism
GEO Series GSE135448. Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.
Crnic Institute Human Trisome Project - Trisomy 21 Model Atlas: PolyA RNA-seq from adult WT and Dp16 mouse liver tissue ± high fat diet
GEO Series GSE296500. Mus musculus. 45 samples. Type: Expression profiling by high throughput sequencing.
Ketogenic diet therapy for pediatric epilepsy is associated with alterations in the human gut microbiome that confer seizure resistance in mice
GEO Series GSE225682. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing.
Predicting a human gut microbiota's response to diet in gnotobiotic mice.
GEO Series GSE26687. Blautia hydrogenotrophica DSM 10507; Escherichia coli str. K-12 substr. MG1655; Marvinbryantia formatexigens DSM 14469; Collinsella aerofaciens ATCC 25986; Bacteria; [Clostridium] symbiosum; Bacteroides thetaiotaomicron VPI-5482; Bacteroides ovatus ATCC 8483; Bacteroides caccae ATCC 43185; Agathobacter rectalis ATCC 33656; Desulfovibrio piger GOR1. 490 samples. Type: Expression profiling by high throughput sequencing; Other.
Hyperandrogenemia and western-style diet act synergistically on transcription and DNA methylation in visceral adipose tissue of a non-human primate model [RNA-Seq]
GEO Series GSE124707. Macaca mulatta. 24 samples. Type: Expression profiling by high throughput sequencing.
Data from: Effects of diet on resource utilization by a model human gut microbiota containing Bacteroides cellulosilyticus WH2, a symbiont with an extensive glycobiome
The human gut microbiota is an important metabolic organ. However, little is known about how its individual species interact, establish dominant positions, and respond to changes in environmental factors such as diet. In the current study, gnotobiotic mice colonized with a simplified model microbiota composed of 12 sequenced human gut bacterial species were fed oscillating diets of disparate composition. Rapid, reproducible and reversible changes in community structure were observed. Time series microbial RNA-Seq analyses revealed staggered functional responses to diet shifts throughout the community that were heavily focused on carbohydrate and amino acid metabolism. High-resolution shotgun metaproteomics confirmed many of these responses at a protein level. One member, Bacteroides cellulosilyticus WH2, proved exceptionally fit regardless of diet. Its genome encoded more carbohydrate active enzymes than any known Bacteroidetes. Transcriptional profiling indicated that B. cellulosilyticus WH2 is an adaptive forager that tailors its versatile carbohydrate utilization strategy to available dietary polysaccharides, with a strong emphasis on plant-derived xylans abundant in dietary staples like cereal grains. Two highly expressed, diet-specific polysaccharide utilization loci (PULs) in B. cellulosilyticus WH2 were identified, one with characteristics of xylan utilization systems. Introduction of a B. cellulosilyticus WH2 library comprising 26,750 isogenic transposon mutants into gnotobiotic mice along with other model community members confirmed that these loci represent critical diet-specific fitness determinants. The specific carbohydrates that trigger overexpression of these two loci and many of the organism's 111 other predicted PULs were identified by RNA-Seq during in vitro growth on 31 distinct carbohydrate substrates, allowing us to better interpret in vivo RNA-Seq and proteomics data. These results offer insight into how gut microbes adapt to dietary perturbations, both at a community level and from the perspective of a well-adapted symbiont with exceptional saccharolytic capabilities, and illustrate the value of studying defined models of the human gut microbiota.
Effect of Yakult Ingestion on Diet-induced Insulin Resistance in Humans
ClinicalTrials.gov study NCT03037918. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.